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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Millions
 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Operating activities:    
Net income $ 1,007.7 $ 1,345.4
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation and loss on disposal of property, plant, and equipment 239.4 208.5
Amortization of intangible assets 20.2 20.8
Gain on sale of business (3.8) 0.0
Loss (gain) on investments, accretion, and amortization, net 43.4 (2.1)
Deferred income taxes (102.0) (40.6)
Share-based compensation expense 385.6 331.4
Amortization of contract acquisition assets 20.7 15.5
Changes in operating assets and liabilities, net of effects of acquisitions:    
Accounts receivable (67.2) (54.7)
Inventory (419.1) (189.2)
Prepaids and other assets (96.8) (216.7)
Accounts payable 26.3 35.8
Accrued compensation and employee benefits (41.9) 30.3
Deferred revenue (21.2) 2.3
Other liabilities 61.6 35.0
Net cash provided by operating activities 1,052.9 1,521.7
Investing activities:    
Purchase of investments (1,393.6) (5,213.7)
Proceeds from sales of investments 59.6 72.4
Proceeds from maturities of investments 2,536.3 3,532.1
Purchase of property, plant, and equipment and intellectual property (394.7) (202.6)
Acquisition of businesses, net of cash, and other investing activities (11.6) (8.7)
Net cash provided by (used in) investing activities 796.0 (1,820.5)
Financing activities:    
Proceeds from issuance of common stock relating to employee stock plans 188.6 244.8
Taxes paid related to net share settlement of equity awards (187.3) (201.2)
Repurchase of common stock (1,606.6) 0.0
Payment of deferred purchase consideration (3.5) (19.2)
Net cash provided by (used in) financing activities (1,608.8) 24.4
Effect of exchange rate changes on cash, cash equivalents, and restricted cash 7.9 (2.3)
Net increase (decrease) in cash, cash equivalents, and restricted cash 248.0 (276.7)
Cash, cash equivalents, and restricted cash, beginning of period 1,306.0 1,638.5
Cash, cash equivalents, and restricted cash, end of period $ 1,554.0 $ 1,361.8