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Income Taxes - Additional Information (Details) - USD ($) $ in Millions | 12 Months Ended |
--- | --- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Income Tax Holiday [Line Items] |  |  |  |
Deferred tax remeasurement due to Swiss Tax Reform | $ 0.0 | $ (66.4) | $ 0.0 |
Valuation allowance | (168.6) | (104.6) |  |
Gross interest related to unrecognized tax benefits accrued | 21.0 | 14.9 | 11.0 |
Total gross unrecognized tax benefits | 252.6 | 222.5 | $ 176.3 | $ 96.7
Unrecognized tax benefits that would impact effective tax rate | 187.4 |  |  |
Net increase in gross unrecognized tax benefits |  | 39.3 |  |
Interest and penalties related to unrecognized tax benefits accrued |  | $ 13.6 |  |
Domestic and Foreign |  |  |  |
Income Tax Holiday [Line Items] |  |  |  |
Net operating loss carryforwards | 27.4 |  |  |
State and Local Jurisdiction | CALIFORNIA | Research Tax Credit Carryforward |  |  |  |
Income Tax Holiday [Line Items] |  |  |  |
Research and development credit carryforwards | $ 221.9 |  |  |

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- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c) -URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32537-109319 + Details
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