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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2022
Income Tax Disclosure [Abstract]  
Schedule Of Income Before Provision For Income Taxes
Income before provision for income taxes for the years ended December 31, 2022, 2021, and 2020, consisted of the following (in millions):
 Years Ended December 31,
 202220212020
U.S.$956.7 $1,298.7 $926.8 
Foreign650.1 591.6 280.2 
Total income before provision for income taxes$1,606.8 $1,890.3 $1,207.0 
Schedule Of Provision For Income Taxes
The provision for income taxes for the years ended December 31, 2022, 2021, and 2020, consisted of the following (in millions):
 Years Ended December 31,
 202220212020
Current
Federal$350.4 $158.8 $34.2 
State49.2 17.3 21.5 
Foreign48.1 50.1 26.9 
447.7 226.2 82.6 
Deferred
Federal(188.8)(21.4)23.8 
State(16.4)0.5 1.6 
Foreign19.9 (43.1)32.2 
(185.3)(64.0)57.6 
Total income tax expense$262.4 $162.2 $140.2 
Schedule Of Income Tax Difference From The Statutory Rate
Income tax expense differs from amounts computed by applying the statutory federal income rate of 21% for the years ended December 31, 2022, 2021, and 2020, as a result of the following (in millions):
 Years Ended December 31,
 202220212020
Federal tax at statutory rate$337.4 $397.0 $253.5 
Increase (reduction) in tax resulting from:
State taxes, net of federal benefits34.9 33.1 23.1 
Foreign rate differential(64.2)(54.3)(19.3)
U.S. tax on foreign earnings75.4 40.1 29.3 
Research and development credit
(41.7)(30.7)(37.1)
Share-based compensation not benefited24.1 17.8 14.3 
Unrecognized tax benefit related to share-based compensation3.3 13.6 39.3 
Reversal of unrecognized tax benefits(11.1)(3.0)(4.0)
Excess tax benefits related to share-based compensation (98.7)(185.8)(166.2)
Deferred tax re-measurement— (66.4)— 
Other3.0 0.8 7.3 
Total income tax expense$262.4 $162.2 $140.2 
Schedule Of Deferred Tax Assets
Deferred income taxes reflect tax carryforwards and the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting and the amounts used for income tax purposes. Significant components of the Company’s deferred tax assets and liabilities are as follows (in millions):
 December 31,
 20222021
Deferred tax assets:
Intangible assets$342.8 $369.1 
Capitalized research and development expenditures
172.5 4.8 
Research and development credits156.7 98.5 
Share-based compensation expense121.3 110.9 
Expenses deducted in later years for tax purposes57.5 38.4 
Lease liabilities16.6 15.2 
Net operating losses6.4 9.7 
Net unrealized losses on available-for-sale securities and other45.5 5.3 
Gross deferred tax assets919.3 651.9 
Valuation allowance(168.6)(104.6)
Deferred tax assets750.7 547.3 
Deferred tax liabilities:
Property, plant, and equipment(64.1)(79.4)
Right-of-use assets(11.8)(12.3)
Intangible assets(9.3)(9.7)
Other(1.0)(5.1)
Deferred tax liabilities(86.2)(106.5)
Net deferred tax assets$664.5 $440.8 
Schedule Of Gross Unrecognized Income Tax Benefits
A reconciliation of the beginning and ending amounts of gross unrecognized income tax benefits for the years ended December 31, 2022, 2021, and 2020, are as follows (in millions):
 Years Ended December 31,
 202220212020
Beginning balance$222.5 $176.3 $96.7 
Increases related to tax positions taken during the current year49.5 40.6 40.1 
Increases related to tax positions taken during a prior year4.9 11.2 46.1 
Decreases related to tax positions taken during a prior year(16.5)(1.3)— 
Decreases related to settlements with tax authorities(1.2)(0.2)(0.5)
Decreases related to expiration of statute of limitations(6.6)(4.1)(6.1)
Ending balance$252.6 $222.5 $176.3