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Consolidated Statements Of Cash Flows - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Operating activities:      
Net income $ 1,344.4 $ 1,728.1 $ 1,066.8
Adjustments to reconcile net income to net cash provided by operating activities:      
Depreciation and loss on disposal of property, plant, and equipment, net 338.0 282.8 226.4
Amortization of intangible assets 27.8 27.4 49.8
Gain on sale of business (3.8) 0.0 0.0
Loss (gain) on investments, accretion of discounts, and amortization of premiums on investments, net 49.0 10.6 (55.1)
Deferred income taxes (185.3) (62.6) 57.6
Share-based compensation expense 513.2 449.2 395.4
Amortization of contract acquisition assets 26.6 22.0 17.1
Changes in operating assets and liabilities, net of effects of acquisitions:      
Accounts receivable (159.3) (142.3) 5.7
Inventory (546.6) (256.0) (170.1)
Prepaids and other assets (129.2) (204.9) (111.8)
Accounts payable 21.3 36.0 (32.3)
Accrued compensation and employee benefits 51.5 115.1 (16.6)
Deferred revenue 21.5 32.6 15.0
Other liabilities 121.7 51.4 36.9
Net cash provided by operating activities 1,490.8 2,089.4 1,484.8
Investing activities:      
Purchase of investments (1,399.5) (6,452.0) (4,292.9)
Proceeds from sales of investments 61.1 84.9 800.7
Proceeds from maturities of investments 3,254.4 4,267.8 2,930.8
Purchase of property, plant, and equipment (532.4) (339.5) (341.5)
Acquisition of businesses, net of cash, and intellectual property and other investing activities 12.8 22.7 37.7
Net cash provided by (used in) investing activities 1,370.8 (2,461.5) (940.6)
Financing activities:      
Proceeds from issuance of common stock relating to employee stock plans 233.8 276.5 308.8
Taxes paid related to net share settlement of equity awards (194.2) (211.6) (175.2)
Repurchase of common stock (2,607.4) 0.0 (134.3)
Payment of deferred purchase consideration (4.5) (21.9) (85.0)
Net cash provided by (used in) financing activities (2,572.3) 43.0 (85.7)
Effect of exchange rate changes on cash, cash equivalents, and restricted cash 5.4 (3.4) (2.6)
Net increase (decrease) in cash, cash equivalents, and restricted cash 294.7 (332.5) 455.9
Cash, cash equivalents, and restricted cash, beginning of year 1,306.0 1,638.5 1,182.6
Cash, cash equivalents, and restricted cash, end of year $ 1,600.7 $ 1,306.0 $ 1,638.5