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Income Taxes - Schedule Of Deferred Tax Assets (Details) - USD ($) $ in Millions | Dec. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Deferred tax assets: |  |
Intangible assets | $ 377.5 | $ 420.9
Capitalized research and development expenditures | 468.6 | 306.4
Research and development credits | 240.3 | 193.2
Share-based compensation expense | 155.3 | 135.1
Swiss tax credits | 107.4 | 122.4
Expenses deducted in later years for tax purposes | 67.4 | 55.9
Lease liabilities | 23.0 | 16.5
Net operating losses | 4.5 | 2.8
Net unrealized losses on available-for-sale securities and other | 11.3 | 9.2
Gross deferred tax assets | 1,455.3 | 1,262.4
Valuation allowance | (314.8) | (269.8)
Deferred tax assets | 1,140.5 | 992.6
Deferred tax liabilities: |  |
Property, plant, and equipment | (65.7) | (60.3)
Right-of-use assets | (18.9) | (11.8)
Intangible assets | (8.5) | (9.8)
Other | (2.3) | (0.2)
Deferred tax liabilities | (95.4) | (82.1)
Net deferred tax assets | $ 1,045.1 | $ 910.5

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