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Income Taxes - Additional Information (Details) - USD ($) $ in Millions | 12 Months Ended |
--- | --- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Income Tax Holiday [Line Items] |  |  |  |
Swiss tax benefits, net of valuation allowance | $ 0.0 | $ 92.3 | $ 0.0 |
Swiss tax benefits, valuation allowance |  | 67.3 |  |
One-time tax benefit | 0.0 | 67.1 | 0.0 |
Excise tax accrued | 0.0 |  |  |
Net operating loss carryforwards | 103.1 |  |  |
Swiss tax credit carryforwards | 107.4 | 122.4 |  |
Research and development credit carryforwards | 240.3 | 193.2 |  |
Valuation allowance | 314.8 | 269.8 |  |
Gross interest related to unrecognized tax benefits accrued | 37.0 | 31.2 | 21.0 |
Total gross unrecognized tax benefits | 310.0 | $ 260.4 | $ 252.6 | $ 222.5
Unrecognized tax benefits that would impact effective tax rate | 217.4 |  |  |
Decrease in unrecognized tax benefits is reasonably possible | 65.0 |  |  |
Research Tax Credit Carryforward, Other |  |  |  |
Income Tax Holiday [Line Items] |  |  |  |
Research and development credit carryforwards | 3.7 |  |  |
California Franchise Tax Board | Research Tax Credit Carryforward, State |  |  |  |
Income Tax Holiday [Line Items] |  |  |  |
Research and development credit carryforwards | $ 329.2 |  |  |

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- Definition Amount of decrease reasonably possible in the next twelve months for the unrecognized tax benefit. + References Reference 1: http://fasb.org/us-gaap/role/ref/otherTransitionRef -Topic 740 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 15 -Subparagraph (d)(3) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482685/740-10-50-15 + Details
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