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Goodwill and other intangible assets (Details Textual) - USD ($)
$ in Millions
 3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Indefinite-lived Intangible Assets [Line Items]        
Amortization charges associated with finite-lived intangible assets $ 308 $ 371 $ 1,100 $ 1,100
Total estimated amortization of finite-lived intangible assets for the three months ending December 31, 2017 300   300  
Total estimated amortization of finite-lived intangible assets for 2018 1,200   1,200  
Total estimated amortization of finite-lived intangible assets for 2019 1,100   1,100  
Total estimated amortization of finite-lived intangible assets for 2020 1,100   1,100  
Total estimated amortization of finite-lived intangible assets for 2021 900   900  
Total estimated amortization of finite-lived intangible assets for 2022 900   $ 900  
Other operating expenses [Member] | IPR&D [Member] | AMG 899 [Member]        
Indefinite-lived Intangible Assets [Line Items]        
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill) $ 400