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    <link:label id="lab_us-gaap_RelatedPartyTransactionLineItems_F9C0BFC14FB95A4AAEA370F7D631FB6E_label_en-US" xlink:label="lab_us-gaap_RelatedPartyTransactionLineItems_F9C0BFC14FB95A4AAEA370F7D631FB6E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Related Party Transaction [Line Items]</link:label>
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    <link:label id="lab_us-gaap_EquityMethodInvestmentOwnershipPercentage_93B15BCF2A756306AF0C70F7D6316FF3_terseLabel_en-US" xlink:label="lab_us-gaap_EquityMethodInvestmentOwnershipPercentage_93B15BCF2A756306AF0C70F7D6316FF3" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Ownership interest (in percent) in related party</link:label>
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    <link:label id="lab_amgn_BusinessAcquisitionPercentageofVotingInterestsAcquiredAnnouncementDate_B10B2F34D2C361A684C7711E171731E6_terseLabel_en-US" xlink:label="lab_amgn_BusinessAcquisitionPercentageofVotingInterestsAcquiredAnnouncementDate_B10B2F34D2C361A684C7711E171731E6" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Percentage of interest acquired, announcement date</link:label>
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    <link:label id="lab_us-gaap_DueToRelatedPartiesCurrent_D8BA7B7DD36A14CCF12570F7D63380B8_terseLabel_en-US" xlink:label="lab_us-gaap_DueToRelatedPartiesCurrent_D8BA7B7DD36A14CCF12570F7D63380B8" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Amount due to related party</link:label>
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    <link:label id="lab_us-gaap_LongtermDebtTypeAxis_09174D7AF0279CE2DD2269804FFD5743_terseLabel_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeAxis_09174D7AF0279CE2DD2269804FFD5743" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Long-term Debt, Type [Axis]</link:label>
    <link:label id="lab_us-gaap_LongtermDebtTypeAxis_09174D7AF0279CE2DD2269804FFD5743_label_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeAxis_09174D7AF0279CE2DD2269804FFD5743" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Long-term Debt, Type [Axis]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_09174D7AF0279CE2DD2269804FFD5743" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_09174D7AF0279CE2DD2269804FFD5743" xlink:to="lab_us-gaap_LongtermDebtTypeAxis_09174D7AF0279CE2DD2269804FFD5743" xlink:type="arc" />
    <link:label id="lab_us-gaap_LongtermDebtTypeDomain_DC392774E8C163CEC6F569804FFDBFD9_terseLabel_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeDomain_DC392774E8C163CEC6F569804FFDBFD9" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Long-term Debt, Type [Domain]</link:label>
    <link:label id="lab_us-gaap_LongtermDebtTypeDomain_DC392774E8C163CEC6F569804FFDBFD9_label_en-US" xlink:label="lab_us-gaap_LongtermDebtTypeDomain_DC392774E8C163CEC6F569804FFDBFD9" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Long-term Debt, Type [Domain]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_DC392774E8C163CEC6F569804FFDBFD9" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_DC392774E8C163CEC6F569804FFDBFD9" xlink:to="lab_us-gaap_LongtermDebtTypeDomain_DC392774E8C163CEC6F569804FFDBFD9" xlink:type="arc" />
    <link:label id="lab_us-gaap_SeniorNotesMember_989595CC72EB9CCBE89069804FFD369C_terseLabel_en-US" xlink:label="lab_us-gaap_SeniorNotesMember_989595CC72EB9CCBE89069804FFD369C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Senior notes [Member]</link:label>
    <link:label id="lab_us-gaap_SeniorNotesMember_989595CC72EB9CCBE89069804FFD369C_label_en-US" xlink:label="lab_us-gaap_SeniorNotesMember_989595CC72EB9CCBE89069804FFD369C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Senior Notes [Member]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SeniorNotesMember" xlink:label="loc_us-gaap_SeniorNotesMember_989595CC72EB9CCBE89069804FFD369C" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SeniorNotesMember_989595CC72EB9CCBE89069804FFD369C" xlink:to="lab_us-gaap_SeniorNotesMember_989595CC72EB9CCBE89069804FFD369C" xlink:type="arc" />
    <link:label id="lab_us-gaap_CommercialPaperMember_6A9682FBAD337A06CFE969804FFDA22D_terseLabel_en-US" xlink:label="lab_us-gaap_CommercialPaperMember_6A9682FBAD337A06CFE969804FFDA22D" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Commercial Paper [Member]</link:label>
    <link:label id="lab_us-gaap_CommercialPaperMember_6A9682FBAD337A06CFE969804FFDA22D_label_en-US" xlink:label="lab_us-gaap_CommercialPaperMember_6A9682FBAD337A06CFE969804FFDA22D" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Commercial Paper [Member]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommercialPaperMember" xlink:label="loc_us-gaap_CommercialPaperMember_6A9682FBAD337A06CFE969804FFDA22D" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommercialPaperMember_6A9682FBAD337A06CFE969804FFDA22D" xlink:to="lab_us-gaap_CommercialPaperMember_6A9682FBAD337A06CFE969804FFDA22D" xlink:type="arc" />
    <link:label id="lab_us-gaap_DebtInstrumentAxis_4B6CD2EE538DACD6AB7F69804FFD3243_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentAxis_4B6CD2EE538DACD6AB7F69804FFD3243" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Debt Instrument [Axis]</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentAxis_4B6CD2EE538DACD6AB7F69804FFD3243_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentAxis_4B6CD2EE538DACD6AB7F69804FFD3243" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Instrument [Axis]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_4B6CD2EE538DACD6AB7F69804FFD3243" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentAxis_4B6CD2EE538DACD6AB7F69804FFD3243" xlink:to="lab_us-gaap_DebtInstrumentAxis_4B6CD2EE538DACD6AB7F69804FFD3243" xlink:type="arc" />
    <link:label id="lab_us-gaap_DebtInstrumentNameDomain_8536C2D18732A844A86269804FFE2FA2_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentNameDomain_8536C2D18732A844A86269804FFE2FA2" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Debt Instrument, Name [Domain]</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentNameDomain_8536C2D18732A844A86269804FFE2FA2_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentNameDomain_8536C2D18732A844A86269804FFE2FA2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Instrument, Name [Domain]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_8536C2D18732A844A86269804FFE2FA2" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_8536C2D18732A844A86269804FFE2FA2" xlink:to="lab_us-gaap_DebtInstrumentNameDomain_8536C2D18732A844A86269804FFE2FA2" xlink:type="arc" />
    <link:label id="lab_amgn_OnePointNineZeroNotesDue2019Member_EC3F822B0756EEC5484469804FFE6D5A_terseLabel_en-US" xlink:label="lab_amgn_OnePointNineZeroNotesDue2019Member_EC3F822B0756EEC5484469804FFE6D5A" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">1.90% notes due 2019 (1.90% 2019 Notes) [Member]</link:label>
    <link:label id="lab_amgn_OnePointNineZeroNotesDue2019Member_EC3F822B0756EEC5484469804FFE6D5A_label_en-US" xlink:label="lab_amgn_OnePointNineZeroNotesDue2019Member_EC3F822B0756EEC5484469804FFE6D5A" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">One Point Nine Zero Notes Due 2019 [Member]</link:label>
    <link:label id="lab_amgn_OnePointNineZeroNotesDue2019Member_EC3F822B0756EEC5484469804FFE6D5A_documentation_en-US" xlink:label="lab_amgn_OnePointNineZeroNotesDue2019Member_EC3F822B0756EEC5484469804FFE6D5A" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">One Point Nine Zero Notes Due 2019 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_OnePointNineZeroNotesDue2019Member" xlink:label="loc_amgn_OnePointNineZeroNotesDue2019Member_EC3F822B0756EEC5484469804FFE6D5A" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OnePointNineZeroNotesDue2019Member_EC3F822B0756EEC5484469804FFE6D5A" xlink:to="lab_amgn_OnePointNineZeroNotesDue2019Member_EC3F822B0756EEC5484469804FFE6D5A" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointTwoZeroNotesDue2020Member_990991C40A25106DCEB669804FFE37B5_terseLabel_en-US" xlink:label="lab_amgn_TwoPointTwoZeroNotesDue2020Member_990991C40A25106DCEB669804FFE37B5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.20% notes due 2020 (2.20% 2020 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoZeroNotesDue2020Member_990991C40A25106DCEB669804FFE37B5_label_en-US" xlink:label="lab_amgn_TwoPointTwoZeroNotesDue2020Member_990991C40A25106DCEB669804FFE37B5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point Two Zero Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoZeroNotesDue2020Member_990991C40A25106DCEB669804FFE37B5_documentation_en-US" xlink:label="lab_amgn_TwoPointTwoZeroNotesDue2020Member_990991C40A25106DCEB669804FFE37B5" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point Two Zero Notes Due 2020 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointTwoZeroNotesDue2020Member" xlink:label="loc_amgn_TwoPointTwoZeroNotesDue2020Member_990991C40A25106DCEB669804FFE37B5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointTwoZeroNotesDue2020Member_990991C40A25106DCEB669804FFE37B5" xlink:to="lab_amgn_TwoPointTwoZeroNotesDue2020Member_990991C40A25106DCEB669804FFE37B5" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointSixFiveNotesDue2022Member_A9BC89E09A7507DDC11269804FFE9525_terseLabel_en-US" xlink:label="lab_amgn_TwoPointSixFiveNotesDue2022Member_A9BC89E09A7507DDC11269804FFE9525" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.65% notes due 2022 (2.65% 2022 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSixFiveNotesDue2022Member_A9BC89E09A7507DDC11269804FFE9525_label_en-US" xlink:label="lab_amgn_TwoPointSixFiveNotesDue2022Member_A9BC89E09A7507DDC11269804FFE9525" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point Six Five Notes Due 2022 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSixFiveNotesDue2022Member_A9BC89E09A7507DDC11269804FFE9525_documentation_en-US" xlink:label="lab_amgn_TwoPointSixFiveNotesDue2022Member_A9BC89E09A7507DDC11269804FFE9525" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point Six Five Notes Due 2022 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointSixFiveNotesDue2022Member" xlink:label="loc_amgn_TwoPointSixFiveNotesDue2022Member_A9BC89E09A7507DDC11269804FFE9525" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointSixFiveNotesDue2022Member_A9BC89E09A7507DDC11269804FFE9525" xlink:to="lab_amgn_TwoPointSixFiveNotesDue2022Member_A9BC89E09A7507DDC11269804FFE9525" xlink:type="arc" />
    <link:label id="lab_amgn_ThreePointTwoZeroNotesDue2027Member_E423C0BA20142BF9074269804FFE2BE5_terseLabel_en-US" xlink:label="lab_amgn_ThreePointTwoZeroNotesDue2027Member_E423C0BA20142BF9074269804FFE2BE5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">3.20% notes due 2027 (3.20% 2027 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointTwoZeroNotesDue2027Member_E423C0BA20142BF9074269804FFE2BE5_label_en-US" xlink:label="lab_amgn_ThreePointTwoZeroNotesDue2027Member_E423C0BA20142BF9074269804FFE2BE5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Three Point Two Zero Notes Due 2027 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointTwoZeroNotesDue2027Member_E423C0BA20142BF9074269804FFE2BE5_documentation_en-US" xlink:label="lab_amgn_ThreePointTwoZeroNotesDue2027Member_E423C0BA20142BF9074269804FFE2BE5" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Three Point Two Zero Notes Due 2027 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_ThreePointTwoZeroNotesDue2027Member" xlink:label="loc_amgn_ThreePointTwoZeroNotesDue2027Member_E423C0BA20142BF9074269804FFE2BE5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointTwoZeroNotesDue2027Member_E423C0BA20142BF9074269804FFE2BE5" xlink:to="lab_amgn_ThreePointTwoZeroNotesDue2027Member_E423C0BA20142BF9074269804FFE2BE5" xlink:type="arc" />
    <link:label id="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_1F40D03F4F90BB96B78C69804FFE86BD_terseLabel_en-US" xlink:label="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_1F40D03F4F90BB96B78C69804FFE86BD" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">1.85% notes due 2021 (1.85% 2021 Notes) [Member]</link:label>
    <link:label id="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_1F40D03F4F90BB96B78C69804FFE86BD_label_en-US" xlink:label="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_1F40D03F4F90BB96B78C69804FFE86BD" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">One Point Eight Five Percent Notes Due Two Zero Two One [Member]</link:label>
    <link:label id="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_1F40D03F4F90BB96B78C69804FFE86BD_documentation_en-US" xlink:label="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_1F40D03F4F90BB96B78C69804FFE86BD" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">One Point Eight Five Percent Notes Due Two Zero Two One [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember" xlink:label="loc_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_1F40D03F4F90BB96B78C69804FFE86BD" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_1F40D03F4F90BB96B78C69804FFE86BD" xlink:to="lab_amgn_OnePointEightFivePercentNotesDueTwoZeroTwoOneMember_1F40D03F4F90BB96B78C69804FFE86BD" xlink:type="arc" />
    <link:label id="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_9E1E2CE104F98CBECF7569804FFE5AAB_terseLabel_en-US" xlink:label="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_9E1E2CE104F98CBECF7569804FFE5AAB" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">1.25% notes due 2022 (1.25% 2022 euro Notes) [Member]</link:label>
    <link:label id="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_9E1E2CE104F98CBECF7569804FFE5AAB_label_en-US" xlink:label="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_9E1E2CE104F98CBECF7569804FFE5AAB" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">One Point Two Five Percent Euro Notes due Two Zero Two Two [Member]</link:label>
    <link:label id="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_9E1E2CE104F98CBECF7569804FFE5AAB_documentation_en-US" xlink:label="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_9E1E2CE104F98CBECF7569804FFE5AAB" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">One Point Two Five Percent Euro Notes due Two Zero Two Two [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember" xlink:label="loc_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_9E1E2CE104F98CBECF7569804FFE5AAB" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_9E1E2CE104F98CBECF7569804FFE5AAB" xlink:to="lab_amgn_OnePointTwoFivePercentEuroNotesdueTwoZeroTwoTwoMember_9E1E2CE104F98CBECF7569804FFE5AAB" xlink:type="arc" />
    <link:label id="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_8DB5B8A1B300BE1E08BD69804FFEC2B5_terseLabel_en-US" xlink:label="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_8DB5B8A1B300BE1E08BD69804FFEC2B5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">0.41% 2023 Swiss franc Bonds [Member]</link:label>
    <link:label id="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_8DB5B8A1B300BE1E08BD69804FFEC2B5_label_en-US" xlink:label="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_8DB5B8A1B300BE1E08BD69804FFEC2B5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Zero Point Forty One Percent Swiss Franc Bonds Due Two Thousand Twenty Three [Member]</link:label>
    <link:label id="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_8DB5B8A1B300BE1E08BD69804FFEC2B5_documentation_en-US" xlink:label="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_8DB5B8A1B300BE1E08BD69804FFEC2B5" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Zero Point Forty One Percent Swiss Franc Bonds Due Two Thousand Twenty Three [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember" xlink:label="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_8DB5B8A1B300BE1E08BD69804FFEC2B5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_8DB5B8A1B300BE1E08BD69804FFEC2B5" xlink:to="lab_amgn_ZeroPointFortyOnePercentSwissFrancBondsDueTwoThousandTwentyThreeMember_8DB5B8A1B300BE1E08BD69804FFEC2B5" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_D2FC04F71124051AD59169804FFE353F_terseLabel_en-US" xlink:label="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_D2FC04F71124051AD59169804FFE353F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.25% notes due 2023 (2.25% 2023 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_D2FC04F71124051AD59169804FFE353F_label_en-US" xlink:label="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_D2FC04F71124051AD59169804FFE353F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point Two Five Percent Notes Due Two Zero Two Three [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_D2FC04F71124051AD59169804FFE353F_documentation_en-US" xlink:label="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_D2FC04F71124051AD59169804FFE353F" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point Two Five Percent Notes Due Two Zero Two Three [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember" xlink:label="loc_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_D2FC04F71124051AD59169804FFE353F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_D2FC04F71124051AD59169804FFE353F" xlink:to="lab_amgn_TwoPointTwoFivePercentNotesDueTwoZeroTwoThreeMember_D2FC04F71124051AD59169804FFE353F" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_F03D3E1D72083CE78E2269804FFEDE41_terseLabel_en-US" xlink:label="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_F03D3E1D72083CE78E2269804FFEDE41" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.00% 2026 euro Notes [Member]</link:label>
    <link:label id="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_F03D3E1D72083CE78E2269804FFEDE41_label_en-US" xlink:label="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_F03D3E1D72083CE78E2269804FFEDE41" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Percent Euro Notes Due Two Thousand Twenty Six [Member]</link:label>
    <link:label id="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_F03D3E1D72083CE78E2269804FFEDE41_documentation_en-US" xlink:label="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_F03D3E1D72083CE78E2269804FFEDE41" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Percent Euro Notes Due Two Thousand Twenty Six [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember" xlink:label="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_F03D3E1D72083CE78E2269804FFEDE41" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_F03D3E1D72083CE78E2269804FFEDE41" xlink:to="lab_amgn_TwoPercentEuroNotesDueTwoThousandTwentySixMember_F03D3E1D72083CE78E2269804FFEDE41" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_1783132884C4F1393AEE69804FFE9967_terseLabel_en-US" xlink:label="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_1783132884C4F1393AEE69804FFE9967" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.60% notes due 2026 (2.60% 2026 notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_1783132884C4F1393AEE69804FFE9967_label_en-US" xlink:label="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_1783132884C4F1393AEE69804FFE9967" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point Six Zero Notes Due Two Zero Two Six [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_1783132884C4F1393AEE69804FFE9967_documentation_en-US" xlink:label="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_1783132884C4F1393AEE69804FFE9967" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point Six Zero Notes Due Two Zero Two Six [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember" xlink:label="loc_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_1783132884C4F1393AEE69804FFE9967" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_1783132884C4F1393AEE69804FFE9967" xlink:to="lab_amgn_TwoPointSixZeroNotesDueTwoZeroTwoSixMember_1783132884C4F1393AEE69804FFE9967" xlink:type="arc" />
    <link:label id="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_8BE9016E6027D207029969804FFF3FCD_terseLabel_en-US" xlink:label="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_8BE9016E6027D207029969804FFF3FCD" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">4.40% notes due 2045 (4.40% 2045 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_8BE9016E6027D207029969804FFF3FCD_label_en-US" xlink:label="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_8BE9016E6027D207029969804FFF3FCD" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Four Point Four Zero Percent Notes Due Two Zero Four Five [Member]</link:label>
    <link:label id="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_8BE9016E6027D207029969804FFF3FCD_documentation_en-US" xlink:label="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_8BE9016E6027D207029969804FFF3FCD" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Four Point Four Zero Percent Notes Due Two Zero Four Five [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember" xlink:label="loc_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_8BE9016E6027D207029969804FFF3FCD" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_8BE9016E6027D207029969804FFF3FCD" xlink:to="lab_amgn_FourPointFourZeroPercentNotesDueTwoZeroFourFiveMember_8BE9016E6027D207029969804FFF3FCD" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_4F7D3D4E62309D98914269804FFF5811_terseLabel_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_4F7D3D4E62309D98914269804FFF5811" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.125% notes due 2020 (2.125% 2020 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_4F7D3D4E62309D98914269804FFF5811_label_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_4F7D3D4E62309D98914269804FFF5811" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point One Two Five Percent Notes Due Two Zero Two Zero [Member]</link:label>
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_4F7D3D4E62309D98914269804FFF5811_documentation_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_4F7D3D4E62309D98914269804FFF5811" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point One Two Five Percent Notes Due Two Zero Two Zero [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember" xlink:label="loc_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_4F7D3D4E62309D98914269804FFF5811" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_4F7D3D4E62309D98914269804FFF5811" xlink:to="lab_amgn_TwoPointOneTwoFivePercentNotesDueTwoZeroTwoZeroMember_4F7D3D4E62309D98914269804FFF5811" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_98F99C551D43DDE4A97069804FFFEBCB_terseLabel_en-US" xlink:label="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_98F99C551D43DDE4A97069804FFFEBCB" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.70% notes due 2022 (2.70% 2022 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_98F99C551D43DDE4A97069804FFFEBCB_label_en-US" xlink:label="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_98F99C551D43DDE4A97069804FFFEBCB" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point Seven Zero Percent Notes Due Two Zero Two Two [Member]</link:label>
    <link:label id="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_98F99C551D43DDE4A97069804FFFEBCB_documentation_en-US" xlink:label="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_98F99C551D43DDE4A97069804FFFEBCB" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point Seven Zero Percent Notes Due Two Zero Two Two [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember" xlink:label="loc_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_98F99C551D43DDE4A97069804FFFEBCB" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_98F99C551D43DDE4A97069804FFFEBCB" xlink:to="lab_amgn_TwoPointSevenZeroPercentNotesDueTwoZeroTwoTwoMember_98F99C551D43DDE4A97069804FFFEBCB" xlink:type="arc" />
    <link:label id="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_07A3F76D3EDF898D950369804FFF4ADE_terseLabel_en-US" xlink:label="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_07A3F76D3EDF898D950369804FFF4ADE" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">3.125% notes due 2025 (3.125% 2025 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_07A3F76D3EDF898D950369804FFF4ADE_label_en-US" xlink:label="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_07A3F76D3EDF898D950369804FFF4ADE" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Three Point One Two Five Percent Notes Due Two Zero Two Five [Member]</link:label>
    <link:label id="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_07A3F76D3EDF898D950369804FFF4ADE_documentation_en-US" xlink:label="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_07A3F76D3EDF898D950369804FFF4ADE" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Three Point One Two Five Percent Notes Due Two Zero Two Five [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember" xlink:label="loc_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_07A3F76D3EDF898D950369804FFF4ADE" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_07A3F76D3EDF898D950369804FFF4ADE" xlink:to="lab_amgn_ThreePointOneTwoFivePercentNotesDueTwoZeroTwoFiveMember_07A3F76D3EDF898D950369804FFF4ADE" xlink:type="arc" />
    <link:label id="lab_us-gaap_DebtInstrumentLineItems_3111D8DF0DA6E65601AE69804FFF7B88_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentLineItems_3111D8DF0DA6E65601AE69804FFF7B88" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Debt Instrument [Line Items]</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentLineItems_3111D8DF0DA6E65601AE69804FFF7B88_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentLineItems_3111D8DF0DA6E65601AE69804FFF7B88" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Instrument [Line Items]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_3111D8DF0DA6E65601AE69804FFF7B88" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentLineItems_3111D8DF0DA6E65601AE69804FFF7B88" xlink:to="lab_us-gaap_DebtInstrumentLineItems_3111D8DF0DA6E65601AE69804FFF7B88" xlink:type="arc" />
    <link:label id="lab_us-gaap_DebtInstrumentFaceAmount_E7D8E1242203A76F99F769804FFFA4E5_verboseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentFaceAmount_E7D8E1242203A76F99F769804FFFA4E5" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Aggregate principal amount of notes issued</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentFaceAmount_E7D8E1242203A76F99F769804FFFA4E5_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentFaceAmount_E7D8E1242203A76F99F769804FFFA4E5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Instrument, Face Amount</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_E7D8E1242203A76F99F769804FFFA4E5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentFaceAmount_E7D8E1242203A76F99F769804FFFA4E5" xlink:to="lab_us-gaap_DebtInstrumentFaceAmount_E7D8E1242203A76F99F769804FFFA4E5" xlink:type="arc" />
    <link:label id="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage_CE1FDFDF7FCF5D8F31E169804FFFE81F_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage_CE1FDFDF7FCF5D8F31E169804FFFE81F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Stated contractual interest rate on note</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage_CE1FDFDF7FCF5D8F31E169804FFFE81F_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage_CE1FDFDF7FCF5D8F31E169804FFFE81F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Instrument, Interest Rate, Stated Percentage</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_CE1FDFDF7FCF5D8F31E169804FFFE81F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_CE1FDFDF7FCF5D8F31E169804FFFE81F" xlink:to="lab_us-gaap_DebtInstrumentInterestRateStatedPercentage_CE1FDFDF7FCF5D8F31E169804FFFE81F" xlink:type="arc" />
    <link:label id="lab_us-gaap_DebtInstrumentUnamortizedPremium_61595FA1C61A93256E3769804FFF1E73_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentUnamortizedPremium_61595FA1C61A93256E3769804FFF1E73" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Debt instrument, unamortized premium</link:label>
    <link:label id="lab_us-gaap_DebtInstrumentUnamortizedPremium_61595FA1C61A93256E3769804FFF1E73_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentUnamortizedPremium_61595FA1C61A93256E3769804FFF1E73" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Instrument, Unamortized Premium</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentUnamortizedPremium" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedPremium_61595FA1C61A93256E3769804FFF1E73" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtInstrumentUnamortizedPremium_61595FA1C61A93256E3769804FFF1E73" xlink:to="lab_us-gaap_DebtInstrumentUnamortizedPremium_61595FA1C61A93256E3769804FFF1E73" xlink:type="arc" />
    <link:label id="lab_us-gaap_ShortTermBankLoansAndNotesPayable_DB43F280DB9FA8B263A169804FFF0FA8_terseLabel_en-US" xlink:label="lab_us-gaap_ShortTermBankLoansAndNotesPayable_DB43F280DB9FA8B263A169804FFF0FA8" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Short-term loan</link:label>
    <link:label id="lab_us-gaap_ShortTermBankLoansAndNotesPayable_DB43F280DB9FA8B263A169804FFF0FA8_label_en-US" xlink:label="lab_us-gaap_ShortTermBankLoansAndNotesPayable_DB43F280DB9FA8B263A169804FFF0FA8" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Short-term Bank Loans and Notes Payable</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShortTermBankLoansAndNotesPayable" xlink:label="loc_us-gaap_ShortTermBankLoansAndNotesPayable_DB43F280DB9FA8B263A169804FFF0FA8" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ShortTermBankLoansAndNotesPayable_DB43F280DB9FA8B263A169804FFF0FA8" xlink:to="lab_us-gaap_ShortTermBankLoansAndNotesPayable_DB43F280DB9FA8B263A169804FFF0FA8" xlink:type="arc" />
    <link:label id="lab_amgn_MaximumBorrowingCapacityUnderCommercialPaper_95418585423397B8007C69804FFF6969_terseLabel_en-US" xlink:label="lab_amgn_MaximumBorrowingCapacityUnderCommercialPaper_95418585423397B8007C69804FFF6969" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Commercial paper, maximum borrowing capacity</link:label>
    <link:label id="lab_amgn_MaximumBorrowingCapacityUnderCommercialPaper_95418585423397B8007C69804FFF6969_label_en-US" xlink:label="lab_amgn_MaximumBorrowingCapacityUnderCommercialPaper_95418585423397B8007C69804FFF6969" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Maximum Borrowing Capacity Under Commercial Paper</link:label>
    <link:label id="lab_amgn_MaximumBorrowingCapacityUnderCommercialPaper_95418585423397B8007C69804FFF6969_documentation_en-US" xlink:label="lab_amgn_MaximumBorrowingCapacityUnderCommercialPaper_95418585423397B8007C69804FFF6969" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Maximum Borrowing Capacity Under Commercial Paper Program.</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_MaximumBorrowingCapacityUnderCommercialPaper" xlink:label="loc_amgn_MaximumBorrowingCapacityUnderCommercialPaper_95418585423397B8007C69804FFF6969" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_MaximumBorrowingCapacityUnderCommercialPaper_95418585423397B8007C69804FFF6969" xlink:to="lab_amgn_MaximumBorrowingCapacityUnderCommercialPaper_95418585423397B8007C69804FFF6969" xlink:type="arc" />
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    <link:label id="lab_amgn_SensiparMimparaMember_67F3D366F56772DD7B17527D896B7808_label_en-US" xlink:label="lab_amgn_SensiparMimparaMember_67F3D366F56772DD7B17527D896B7808" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Sensipar Mimpara [Member]</link:label>
    <link:label id="lab_amgn_SensiparMimparaMember_67F3D366F56772DD7B17527D896B7808_documentation_en-US" xlink:label="lab_amgn_SensiparMimparaMember_67F3D366F56772DD7B17527D896B7808" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Sensipar (Mimpara).</link:label>
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    <link:label id="lab_amgn_XgevaMember_3210863D9953CD27F07D527D896B58D8_terseLabel_en-US" xlink:label="lab_amgn_XgevaMember_3210863D9953CD27F07D527D896B58D8" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">XGEVA [Member]</link:label>
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    <link:label id="lab_amgn_EpogenMember_F462F09627A7A52B8379527D896BCFC0_label_en-US" xlink:label="lab_amgn_EpogenMember_F462F09627A7A52B8379527D896BCFC0" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EPOGEN [Member]</link:label>
    <link:label id="lab_amgn_EpogenMember_F462F09627A7A52B8379527D896BCFC0_documentation_en-US" xlink:label="lab_amgn_EpogenMember_F462F09627A7A52B8379527D896BCFC0" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EPOGEN.</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_EpogenMember" xlink:label="loc_amgn_EpogenMember_F462F09627A7A52B8379527D896BCFC0" xlink:type="locator" />
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    <link:label id="lab_amgn_KyprolisMember_B0F9F836AF1C42AA22EE527D896CA15B_label_en-US" xlink:label="lab_amgn_KyprolisMember_B0F9F836AF1C42AA22EE527D896CA15B" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Kyprolis [Member]</link:label>
    <link:label id="lab_amgn_KyprolisMember_B0F9F836AF1C42AA22EE527D896CA15B_documentation_en-US" xlink:label="lab_amgn_KyprolisMember_B0F9F836AF1C42AA22EE527D896CA15B" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Kyprolis [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_KyprolisMember" xlink:label="loc_amgn_KyprolisMember_B0F9F836AF1C42AA22EE527D896CA15B" xlink:type="locator" />
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    <link:label id="lab_amgn_VectibixMember_85DB18E996CEF5D5393F527D896C726F_terseLabel_en-US" xlink:label="lab_amgn_VectibixMember_85DB18E996CEF5D5393F527D896C726F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Vectibix [Member]</link:label>
    <link:label id="lab_amgn_VectibixMember_85DB18E996CEF5D5393F527D896C726F_label_en-US" xlink:label="lab_amgn_VectibixMember_85DB18E996CEF5D5393F527D896C726F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Vectibix [Member]</link:label>
    <link:label id="lab_amgn_VectibixMember_85DB18E996CEF5D5393F527D896C726F_documentation_en-US" xlink:label="lab_amgn_VectibixMember_85DB18E996CEF5D5393F527D896C726F" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Vectibix.</link:label>
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    <link:loc xlink:href="amgn-20171231.xsd#amgn_NplateMember" xlink:label="loc_amgn_NplateMember_4AE45CFA0B4E3BBA5DDB527D896CDE87" xlink:type="locator" />
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    <link:loc xlink:href="amgn-20171231.xsd#amgn_NEUPOGENMember" xlink:label="loc_amgn_NEUPOGENMember_BC5A16D5BAB44E6FF6BE527D896CA14F" xlink:type="locator" />
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    <link:loc xlink:href="amgn-20171231.xsd#amgn_RepathaMember" xlink:label="loc_amgn_RepathaMember_8C5921D61F95BB992451527D896CFFCA" xlink:type="locator" />
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    <link:loc xlink:href="amgn-20171231.xsd#amgn_BLINCYTOMember" xlink:label="loc_amgn_BLINCYTOMember_B05F2307FF548F2CE80B527D896C2F28" xlink:type="locator" />
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    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsFutureAmortizationExpenseAbstract_BA737E98C7149A1E17BC72BC5705344F_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsFutureAmortizationExpenseAbstract_BA737E98C7149A1E17BC72BC5705344F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Net, Amortization Expense, Fiscal Year Maturity [Abstract]</link:label>
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    <link:label id="lab_us-gaap_AmortizationOfIntangibleAssets_D03212717B5DEE1AE5ED72BC57061AF0_terseLabel_en-US" xlink:label="lab_us-gaap_AmortizationOfIntangibleAssets_D03212717B5DEE1AE5ED72BC57061AF0" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Amortization charges associated with finite-lived intangible assets</link:label>
    <link:label id="lab_us-gaap_AmortizationOfIntangibleAssets_D03212717B5DEE1AE5ED72BC57061AF0_label_en-US" xlink:label="lab_us-gaap_AmortizationOfIntangibleAssets_D03212717B5DEE1AE5ED72BC57061AF0" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Amortization of Intangible Assets</link:label>
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    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_AmortizationOfIntangibleAssets_D03212717B5DEE1AE5ED72BC57061AF0" xlink:to="lab_us-gaap_AmortizationOfIntangibleAssets_D03212717B5DEE1AE5ED72BC57061AF0" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6720E1ECB2EBCDE2C05A72BC5706EAAE_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6720E1ECB2EBCDE2C05A72BC5706EAAE" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total estimated amortization of finite- lived intangible assets for 2018</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6720E1ECB2EBCDE2C05A72BC5706EAAE_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6720E1ECB2EBCDE2C05A72BC5706EAAE" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Next Twelve Months</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6720E1ECB2EBCDE2C05A72BC5706EAAE" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6720E1ECB2EBCDE2C05A72BC5706EAAE" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_6720E1ECB2EBCDE2C05A72BC5706EAAE" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_E48A05D494CE69D699B772BC57064202_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_E48A05D494CE69D699B772BC57064202" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total estimated amortization of finite- lived intangible assets for 2019</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_E48A05D494CE69D699B772BC57064202_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_E48A05D494CE69D699B772BC57064202" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Two</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_E48A05D494CE69D699B772BC57064202" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_E48A05D494CE69D699B772BC57064202" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_E48A05D494CE69D699B772BC57064202" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_06C56200FEB735DE2E4072BC5706C9C4_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_06C56200FEB735DE2E4072BC5706C9C4" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total estimated amortization of finite- lived intangible assets for 2020</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_06C56200FEB735DE2E4072BC5706C9C4_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_06C56200FEB735DE2E4072BC5706C9C4" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Three</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_06C56200FEB735DE2E4072BC5706C9C4" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_06C56200FEB735DE2E4072BC5706C9C4" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_06C56200FEB735DE2E4072BC5706C9C4" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_98C111C50AF49486D48872BC5706A5CC_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_98C111C50AF49486D48872BC5706A5CC" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total estimated amortization of finite-lived intangible assets for 2021</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_98C111C50AF49486D48872BC5706A5CC_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_98C111C50AF49486D48872BC5706A5CC" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Four</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_98C111C50AF49486D48872BC5706A5CC" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_98C111C50AF49486D48872BC5706A5CC" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_98C111C50AF49486D48872BC5706A5CC" xlink:type="arc" />
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_A1392FAA84425F87618B72BC57060CF9_terseLabel_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_A1392FAA84425F87618B72BC57060CF9" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total estimated amortization of finite-lived intangible assets for 2022</link:label>
    <link:label id="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_A1392FAA84425F87618B72BC57060CF9_label_en-US" xlink:label="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_A1392FAA84425F87618B72BC57060CF9" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Finite-Lived Intangible Assets, Amortization Expense, Year Five</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_A1392FAA84425F87618B72BC57060CF9" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_A1392FAA84425F87618B72BC57060CF9" xlink:to="lab_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_A1392FAA84425F87618B72BC57060CF9" xlink:type="arc" />
    <link:label id="lab_amgn_InterestAndOtherIncomeMember_DAEC0DE0960FA83A1287FF98F6763D94_verboseLabel_en-US" xlink:label="lab_amgn_InterestAndOtherIncomeMember_DAEC0DE0960FA83A1287FF98F6763D94" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Interest and other income, net [Member]</link:label>
    <link:label id="lab_amgn_InterestAndOtherIncomeMember_DAEC0DE0960FA83A1287FF98F6763D94_label_en-US" xlink:label="lab_amgn_InterestAndOtherIncomeMember_DAEC0DE0960FA83A1287FF98F6763D94" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Interest And Other Income [Member]</link:label>
    <link:label id="lab_amgn_InterestAndOtherIncomeMember_DAEC0DE0960FA83A1287FF98F6763D94_documentation_en-US" xlink:label="lab_amgn_InterestAndOtherIncomeMember_DAEC0DE0960FA83A1287FF98F6763D94" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Interest and other income.</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_InterestAndOtherIncomeMember" xlink:label="loc_amgn_InterestAndOtherIncomeMember_DAEC0DE0960FA83A1287FF98F6763D94" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_InterestAndOtherIncomeMember_DAEC0DE0960FA83A1287FF98F6763D94" xlink:to="lab_amgn_InterestAndOtherIncomeMember_DAEC0DE0960FA83A1287FF98F6763D94" xlink:type="arc" />
    <link:label id="lab_us-gaap_GainLossOnForeignCurrencyDerivativeInstrumentsNotDesignatedAsHedgingInstruments_79F82DE0A2491A943A2BFF98F677AE63_verboseLabel_en-US" xlink:label="lab_us-gaap_GainLossOnForeignCurrencyDerivativeInstrumentsNotDesignatedAsHedgingInstruments_79F82DE0A2491A943A2BFF98F677AE63" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Amount of gain (loss) recognized in interest and other income, net</link:label>
    <link:label id="lab_us-gaap_GainLossOnForeignCurrencyDerivativeInstrumentsNotDesignatedAsHedgingInstruments_79F82DE0A2491A943A2BFF98F677AE63_label_en-US" xlink:label="lab_us-gaap_GainLossOnForeignCurrencyDerivativeInstrumentsNotDesignatedAsHedgingInstruments_79F82DE0A2491A943A2BFF98F677AE63" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Gain (Loss) on Foreign Currency Derivative Instruments Not Designated as Hedging Instruments</link:label>
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    <link:label id="lab_us-gaap_RestructuringCostAndReserveAxis_2F83CAAFFAC9F36F0F44565273DB7C04_terseLabel_en-US" xlink:label="lab_us-gaap_RestructuringCostAndReserveAxis_2F83CAAFFAC9F36F0F44565273DB7C04" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Restructuring Type [Axis]</link:label>
    <link:label id="lab_us-gaap_RestructuringCostAndReserveAxis_2F83CAAFFAC9F36F0F44565273DB7C04_label_en-US" xlink:label="lab_us-gaap_RestructuringCostAndReserveAxis_2F83CAAFFAC9F36F0F44565273DB7C04" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Restructuring Type [Axis]</link:label>
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    <link:label id="lab_us-gaap_EmployeeSeveranceMember_8CFC1C54F4052567175C565273DB87B6_label_en-US" xlink:label="lab_us-gaap_EmployeeSeveranceMember_8CFC1C54F4052567175C565273DB87B6" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Employee Severance [Member]</link:label>
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    <link:label id="lab_us-gaap_OtherRestructuringMember_44D2DF5A71D25589E585565273DBB4E2_label_en-US" xlink:label="lab_us-gaap_OtherRestructuringMember_44D2DF5A71D25589E585565273DBB4E2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Other Restructuring [Member]</link:label>
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    <link:label id="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_4471004A48FF7E6BF1E55326AA24BD2E_label_en-US" xlink:label="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_4471004A48FF7E6BF1E55326AA24BD2E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Derivative Financial Instruments Liabilities Fair Value Disclosure [Abstract]</link:label>
    <link:label id="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_4471004A48FF7E6BF1E55326AA24BD2E_documentation_en-US" xlink:label="lab_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_4471004A48FF7E6BF1E55326AA24BD2E" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Derivative financial instruments liabilities fair value disclosure.</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract" xlink:label="loc_amgn_DerivativeFinancialInstrumentsLiabilitiesFairValueDisclosureAbstract_4471004A48FF7E6BF1E55326AA24BD2E" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_1CE0CF13D6972CB878EE5326AA24D92E_verboseLabel_en-US" xlink:label="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_1CE0CF13D6972CB878EE5326AA24D92E" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Foreign currency contracts</link:label>
    <link:label id="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_1CE0CF13D6972CB878EE5326AA24D92E_label_en-US" xlink:label="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_1CE0CF13D6972CB878EE5326AA24D92E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Foreign Currency Contracts, Liability, Fair Value Disclosure</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure" xlink:label="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_1CE0CF13D6972CB878EE5326AA24D92E" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_1CE0CF13D6972CB878EE5326AA24D92E" xlink:to="lab_us-gaap_ForeignCurrencyContractsLiabilityFairValueDisclosure_1CE0CF13D6972CB878EE5326AA24D92E" xlink:type="arc" />
    <link:label id="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_2A2BF0F06E70CACFF2D35326AA24D64A_terseLabel_en-US" xlink:label="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_2A2BF0F06E70CACFF2D35326AA24D64A" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest rate swap contracts</link:label>
    <link:label id="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_2A2BF0F06E70CACFF2D35326AA24D64A_label_en-US" xlink:label="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_2A2BF0F06E70CACFF2D35326AA24D64A" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Interest Rate Fair Value Hedge Liability at Fair Value</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue" xlink:label="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_2A2BF0F06E70CACFF2D35326AA24D64A" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_2A2BF0F06E70CACFF2D35326AA24D64A" xlink:to="lab_us-gaap_InterestRateFairValueHedgeLiabilityAtFairValue_2A2BF0F06E70CACFF2D35326AA24D64A" xlink:type="arc" />
    <link:label id="lab_us-gaap_BusinessCombinationContingentConsiderationLiability_0C2F28355C553C702BD65326AA245E5F_verboseLabel_en-US" xlink:label="lab_us-gaap_BusinessCombinationContingentConsiderationLiability_0C2F28355C553C702BD65326AA245E5F" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Contingent consideration obligations in connection with business combinations</link:label>
    <link:label id="lab_us-gaap_BusinessCombinationContingentConsiderationLiability_0C2F28355C553C702BD65326AA245E5F_label_en-US" xlink:label="lab_us-gaap_BusinessCombinationContingentConsiderationLiability_0C2F28355C553C702BD65326AA245E5F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Business Combination, Contingent Consideration, Liability</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_0C2F28355C553C702BD65326AA245E5F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_0C2F28355C553C702BD65326AA245E5F" xlink:to="lab_us-gaap_BusinessCombinationContingentConsiderationLiability_0C2F28355C553C702BD65326AA245E5F" xlink:type="arc" />
    <link:label id="lab_us-gaap_LiabilitiesFairValueDisclosure_159524E6032A538C52175326AA24866E_totalLabel_en-US" xlink:label="lab_us-gaap_LiabilitiesFairValueDisclosure_159524E6032A538C52175326AA24866E" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total liabilities</link:label>
    <link:label id="lab_us-gaap_LiabilitiesFairValueDisclosure_159524E6032A538C52175326AA24866E_label_en-US" xlink:label="lab_us-gaap_LiabilitiesFairValueDisclosure_159524E6032A538C52175326AA24866E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Financial and Nonfinancial Liabilities, Fair Value Disclosure</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_159524E6032A538C52175326AA24866E" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_159524E6032A538C52175326AA24866E" xlink:to="lab_us-gaap_LiabilitiesFairValueDisclosure_159524E6032A538C52175326AA24866E" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentNotesDue2017Member_A84EB968EECED9628AE6E6424582B596_terseLabel_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentNotesDue2017Member_A84EB968EECED9628AE6E6424582B596" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.125% notes due 2017 (2.125% 2017 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentNotesDue2017Member_A84EB968EECED9628AE6E6424582B596_label_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentNotesDue2017Member_A84EB968EECED9628AE6E6424582B596" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point One Two Five Percent Notes Due 2017 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentNotesDue2017Member_A84EB968EECED9628AE6E6424582B596_documentation_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentNotesDue2017Member_A84EB968EECED9628AE6E6424582B596" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point One Two Five Percent Notes Due 2017 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointOneTwoFivePercentNotesDue2017Member" xlink:label="loc_amgn_TwoPointOneTwoFivePercentNotesDue2017Member_A84EB968EECED9628AE6E6424582B596" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointOneTwoFivePercentNotesDue2017Member_A84EB968EECED9628AE6E6424582B596" xlink:to="lab_amgn_TwoPointOneTwoFivePercentNotesDue2017Member_A84EB968EECED9628AE6E6424582B596" xlink:type="arc" />
    <link:label id="lab_amgn_FloatingRateNotesDue2017Member_DAF6D1905D842D08BF0BE64245826F50_verboseLabel_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2017Member_DAF6D1905D842D08BF0BE64245826F50" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Floating rate notes due 2017 [Member]</link:label>
    <link:label id="lab_amgn_FloatingRateNotesDue2017Member_DAF6D1905D842D08BF0BE64245826F50_label_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2017Member_DAF6D1905D842D08BF0BE64245826F50" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Floating Rate Notes Due 2017 [Member]</link:label>
    <link:label id="lab_amgn_FloatingRateNotesDue2017Member_DAF6D1905D842D08BF0BE64245826F50_documentation_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2017Member_DAF6D1905D842D08BF0BE64245826F50" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Floating Rate Notes Due 2017 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FloatingRateNotesDue2017Member" xlink:label="loc_amgn_FloatingRateNotesDue2017Member_DAF6D1905D842D08BF0BE64245826F50" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FloatingRateNotesDue2017Member_DAF6D1905D842D08BF0BE64245826F50" xlink:to="lab_amgn_FloatingRateNotesDue2017Member_DAF6D1905D842D08BF0BE64245826F50" xlink:type="arc" />
    <link:label id="lab_amgn_OnePointTwoFivePercentNotesDue2017Member_DB532BFBA500EAF32D66E64245842901_verboseLabel_en-US" xlink:label="lab_amgn_OnePointTwoFivePercentNotesDue2017Member_DB532BFBA500EAF32D66E64245842901" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">1.25% notes due 2017 (1.25% 2017 Notes) [Member]</link:label>
    <link:label id="lab_amgn_OnePointTwoFivePercentNotesDue2017Member_DB532BFBA500EAF32D66E64245842901_label_en-US" xlink:label="lab_amgn_OnePointTwoFivePercentNotesDue2017Member_DB532BFBA500EAF32D66E64245842901" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">One Point Two Five Percent Notes Due 2017 [Member]</link:label>
    <link:label id="lab_amgn_OnePointTwoFivePercentNotesDue2017Member_DB532BFBA500EAF32D66E64245842901_documentation_en-US" xlink:label="lab_amgn_OnePointTwoFivePercentNotesDue2017Member_DB532BFBA500EAF32D66E64245842901" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">One Point Two Five Percent Notes Due 2017 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_OnePointTwoFivePercentNotesDue2017Member" xlink:label="loc_amgn_OnePointTwoFivePercentNotesDue2017Member_DB532BFBA500EAF32D66E64245842901" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_OnePointTwoFivePercentNotesDue2017Member_DB532BFBA500EAF32D66E64245842901" xlink:to="lab_amgn_OnePointTwoFivePercentNotesDue2017Member_DB532BFBA500EAF32D66E64245842901" xlink:type="arc" />
    <link:label id="lab_amgn_FivePointEightFivePercentNotesDue2017Member_E67D584DB92C8206DD1DE6424584F6C0_terseLabel_en-US" xlink:label="lab_amgn_FivePointEightFivePercentNotesDue2017Member_E67D584DB92C8206DD1DE6424584F6C0" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">5.85% notes due 2017 (5.85% 2017 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointEightFivePercentNotesDue2017Member_E67D584DB92C8206DD1DE6424584F6C0_label_en-US" xlink:label="lab_amgn_FivePointEightFivePercentNotesDue2017Member_E67D584DB92C8206DD1DE6424584F6C0" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Five Point Eight Five Percent Notes Due 2017 [Member]</link:label>
    <link:label id="lab_amgn_FivePointEightFivePercentNotesDue2017Member_E67D584DB92C8206DD1DE6424584F6C0_documentation_en-US" xlink:label="lab_amgn_FivePointEightFivePercentNotesDue2017Member_E67D584DB92C8206DD1DE6424584F6C0" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Five Point Eight Five Percent Notes Due 2017 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FivePointEightFivePercentNotesDue2017Member" xlink:label="loc_amgn_FivePointEightFivePercentNotesDue2017Member_E67D584DB92C8206DD1DE6424584F6C0" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePointEightFivePercentNotesDue2017Member_E67D584DB92C8206DD1DE6424584F6C0" xlink:to="lab_amgn_FivePointEightFivePercentNotesDue2017Member_E67D584DB92C8206DD1DE6424584F6C0" xlink:type="arc" />
    <link:label id="lab_amgn_TermLoanDueTwoThousandEighteenMember_4653D3E03141B6BF166DE6424584E495_terseLabel_en-US" xlink:label="lab_amgn_TermLoanDueTwoThousandEighteenMember_4653D3E03141B6BF166DE6424584E495" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Term loan due 2018 [Member]</link:label>
    <link:label id="lab_amgn_TermLoanDueTwoThousandEighteenMember_4653D3E03141B6BF166DE6424584E495_label_en-US" xlink:label="lab_amgn_TermLoanDueTwoThousandEighteenMember_4653D3E03141B6BF166DE6424584E495" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Term Loan Due Two Thousand Eighteen [Member]</link:label>
    <link:label id="lab_amgn_TermLoanDueTwoThousandEighteenMember_4653D3E03141B6BF166DE6424584E495_documentation_en-US" xlink:label="lab_amgn_TermLoanDueTwoThousandEighteenMember_4653D3E03141B6BF166DE6424584E495" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Term Loan Due Two Thousand Eighteen [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TermLoanDueTwoThousandEighteenMember" xlink:label="loc_amgn_TermLoanDueTwoThousandEighteenMember_4653D3E03141B6BF166DE6424584E495" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TermLoanDueTwoThousandEighteenMember_4653D3E03141B6BF166DE6424584E495" xlink:to="lab_amgn_TermLoanDueTwoThousandEighteenMember_4653D3E03141B6BF166DE6424584E495" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointThreeZeroPercentNotesDue2016Member_5E2DD889DAD6F393AD27E6424584432C_verboseLabel_en-US" xlink:label="lab_amgn_TwoPointThreeZeroPercentNotesDue2016Member_5E2DD889DAD6F393AD27E6424584432C" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">2.30% notes due 2016 (2.30% 2016 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointThreeZeroPercentNotesDue2016Member_5E2DD889DAD6F393AD27E6424584432C_label_en-US" xlink:label="lab_amgn_TwoPointThreeZeroPercentNotesDue2016Member_5E2DD889DAD6F393AD27E6424584432C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point Three Zero Percent Notes Due 2016 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointThreeZeroPercentNotesDue2016Member_5E2DD889DAD6F393AD27E6424584432C_documentation_en-US" xlink:label="lab_amgn_TwoPointThreeZeroPercentNotesDue2016Member_5E2DD889DAD6F393AD27E6424584432C" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point Three Zero Percent Notes Due 2016 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointThreeZeroPercentNotesDue2016Member" xlink:label="loc_amgn_TwoPointThreeZeroPercentNotesDue2016Member_5E2DD889DAD6F393AD27E6424584432C" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointThreeZeroPercentNotesDue2016Member_5E2DD889DAD6F393AD27E6424584432C" xlink:to="lab_amgn_TwoPointThreeZeroPercentNotesDue2016Member_5E2DD889DAD6F393AD27E6424584432C" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointFiveZeroPercentNotesDue2016Member_96E96DD08E3577F90148E64245847A37_verboseLabel_en-US" xlink:label="lab_amgn_TwoPointFiveZeroPercentNotesDue2016Member_96E96DD08E3577F90148E64245847A37" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">2.50% notes due 2016 (2.50% 2016 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointFiveZeroPercentNotesDue2016Member_96E96DD08E3577F90148E64245847A37_label_en-US" xlink:label="lab_amgn_TwoPointFiveZeroPercentNotesDue2016Member_96E96DD08E3577F90148E64245847A37" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point Five Zero Percent Notes Due 2016 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointFiveZeroPercentNotesDue2016Member_96E96DD08E3577F90148E64245847A37_documentation_en-US" xlink:label="lab_amgn_TwoPointFiveZeroPercentNotesDue2016Member_96E96DD08E3577F90148E64245847A37" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point Five Zero Percent Notes Due 2016 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointFiveZeroPercentNotesDue2016Member" xlink:label="loc_amgn_TwoPointFiveZeroPercentNotesDue2016Member_96E96DD08E3577F90148E64245847A37" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointFiveZeroPercentNotesDue2016Member_96E96DD08E3577F90148E64245847A37" xlink:to="lab_amgn_TwoPointFiveZeroPercentNotesDue2016Member_96E96DD08E3577F90148E64245847A37" xlink:type="arc" />
    <link:label id="lab_us-gaap_RepaymentsOfShortTermDebt_E67E72BFEFF2A695B04EE6424585BFE4_terseLabel_en-US" xlink:label="lab_us-gaap_RepaymentsOfShortTermDebt_E67E72BFEFF2A695B04EE6424585BFE4" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Repayments of short-term debt</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RepaymentsOfShortTermDebt" xlink:label="loc_us-gaap_RepaymentsOfShortTermDebt_E67E72BFEFF2A695B04EE6424585BFE4" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RepaymentsOfShortTermDebt_E67E72BFEFF2A695B04EE6424585BFE4" xlink:to="lab_us-gaap_RepaymentsOfShortTermDebt_E67E72BFEFF2A695B04EE6424585BFE4" xlink:type="arc" />
    <link:label id="lab_us-gaap_RepaymentsOfLongTermDebt_591D0A1A8355CE73408BE6424585ACFD_terseLabel_en-US" xlink:label="lab_us-gaap_RepaymentsOfLongTermDebt_591D0A1A8355CE73408BE6424585ACFD" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Repayments of debt</link:label>
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    <link:label id="lab_amgn_GainContingencyNumberofAffiliates_5C418286CD66F12996E487B40301BE5F_documentation_en-US" xlink:label="lab_amgn_GainContingencyNumberofAffiliates_5C418286CD66F12996E487B40301BE5F" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Gain Contingency, Number of Affiliates</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_GainContingencyNumberofAffiliates" xlink:label="loc_amgn_GainContingencyNumberofAffiliates_5C418286CD66F12996E487B40301BE5F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_GainContingencyNumberofAffiliates_5C418286CD66F12996E487B40301BE5F" xlink:to="lab_amgn_GainContingencyNumberofAffiliates_5C418286CD66F12996E487B40301BE5F" xlink:type="arc" />
    <link:label id="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_FEB2D38A20C6A74FEDE087B403014FB5_terseLabel_en-US" xlink:label="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_FEB2D38A20C6A74FEDE087B403014FB5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Aount awarded from other party</link:label>
    <link:label id="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_FEB2D38A20C6A74FEDE087B403014FB5_label_en-US" xlink:label="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_FEB2D38A20C6A74FEDE087B403014FB5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Litigation Settlement, Amount Awarded from Other Party</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedFromOtherParty" xlink:label="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_FEB2D38A20C6A74FEDE087B403014FB5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_FEB2D38A20C6A74FEDE087B403014FB5" xlink:to="lab_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_FEB2D38A20C6A74FEDE087B403014FB5" xlink:type="arc" />
    <link:label id="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_5BE9F40D05F8B41B093A87B40301C798_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_5BE9F40D05F8B41B093A87B40301C798" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Loss contingency, patents allegedly infringed</link:label>
    <link:label id="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_5BE9F40D05F8B41B093A87B40301C798_label_en-US" xlink:label="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_5BE9F40D05F8B41B093A87B40301C798" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Loss Contingency, Patents Allegedly Infringed, Number</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyPatentsAllegedlyInfringedNumber" xlink:label="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_5BE9F40D05F8B41B093A87B40301C798" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_5BE9F40D05F8B41B093A87B40301C798" xlink:to="lab_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_5BE9F40D05F8B41B093A87B40301C798" xlink:type="arc" />
    <link:label id="lab_us-gaap_LossContingencyNumberOfPlaintiffs_1D3CE0B6D74FE76BA1B587B403017C96_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingencyNumberOfPlaintiffs_1D3CE0B6D74FE76BA1B587B403017C96" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Loss contingency, number of plaintiffs</link:label>
    <link:label id="lab_us-gaap_LossContingencyNumberOfPlaintiffs_1D3CE0B6D74FE76BA1B587B403017C96_label_en-US" xlink:label="lab_us-gaap_LossContingencyNumberOfPlaintiffs_1D3CE0B6D74FE76BA1B587B403017C96" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Loss Contingency, Number of Plaintiffs</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyNumberOfPlaintiffs" xlink:label="loc_us-gaap_LossContingencyNumberOfPlaintiffs_1D3CE0B6D74FE76BA1B587B403017C96" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingencyNumberOfPlaintiffs_1D3CE0B6D74FE76BA1B587B403017C96" xlink:to="lab_us-gaap_LossContingencyNumberOfPlaintiffs_1D3CE0B6D74FE76BA1B587B403017C96" xlink:type="arc" />
    <link:label id="lab_us-gaap_LossContingencyNewClaimsFiledNumber_F0569392E35D1FF0B47187B55A1C49E2_terseLabel_en-US" xlink:label="lab_us-gaap_LossContingencyNewClaimsFiledNumber_F0569392E35D1FF0B47187B55A1C49E2" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Loss contingency, number of lawsuits</link:label>
    <link:label id="lab_us-gaap_LossContingencyNewClaimsFiledNumber_F0569392E35D1FF0B47187B55A1C49E2_label_en-US" xlink:label="lab_us-gaap_LossContingencyNewClaimsFiledNumber_F0569392E35D1FF0B47187B55A1C49E2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Loss Contingency, New Claims Filed, Number</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyNewClaimsFiledNumber" xlink:label="loc_us-gaap_LossContingencyNewClaimsFiledNumber_F0569392E35D1FF0B47187B55A1C49E2" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LossContingencyNewClaimsFiledNumber_F0569392E35D1FF0B47187B55A1C49E2" xlink:to="lab_us-gaap_LossContingencyNewClaimsFiledNumber_F0569392E35D1FF0B47187B55A1C49E2" xlink:type="arc" />
    <link:label id="lab_amgn_FutureRentalCommitmentsForAbandonedLeases_09D174E4653F7E3460CB87B403015D22_terseLabel_en-US" xlink:label="lab_amgn_FutureRentalCommitmentsForAbandonedLeases_09D174E4653F7E3460CB87B403015D22" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Future rental commitments for abandoned leases</link:label>
    <link:label id="lab_amgn_FutureRentalCommitmentsForAbandonedLeases_09D174E4653F7E3460CB87B403015D22_label_en-US" xlink:label="lab_amgn_FutureRentalCommitmentsForAbandonedLeases_09D174E4653F7E3460CB87B403015D22" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Future Rental Commitments For Abandoned Leases</link:label>
    <link:label id="lab_amgn_FutureRentalCommitmentsForAbandonedLeases_09D174E4653F7E3460CB87B403015D22_documentation_en-US" xlink:label="lab_amgn_FutureRentalCommitmentsForAbandonedLeases_09D174E4653F7E3460CB87B403015D22" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Future rental commitments for abandoned leases.</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FutureRentalCommitmentsForAbandonedLeases" xlink:label="loc_amgn_FutureRentalCommitmentsForAbandonedLeases_09D174E4653F7E3460CB87B403015D22" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FutureRentalCommitmentsForAbandonedLeases_09D174E4653F7E3460CB87B403015D22" xlink:to="lab_amgn_FutureRentalCommitmentsForAbandonedLeases_09D174E4653F7E3460CB87B403015D22" xlink:type="arc" />
    <link:label id="lab_us-gaap_OperatingLeasesFutureMinimumPaymentsReceivable_20B2C3E34464DC0DDBD587B4030107A5_terseLabel_en-US" xlink:label="lab_us-gaap_OperatingLeasesFutureMinimumPaymentsReceivable_20B2C3E34464DC0DDBD587B4030107A5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Future rental income relating to noncancelable subleases of abandoned facilities</link:label>
    <link:label id="lab_us-gaap_OperatingLeasesFutureMinimumPaymentsReceivable_20B2C3E34464DC0DDBD587B4030107A5_label_en-US" xlink:label="lab_us-gaap_OperatingLeasesFutureMinimumPaymentsReceivable_20B2C3E34464DC0DDBD587B4030107A5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Operating Leases, Future Minimum Payments Receivable</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsReceivable" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsReceivable_20B2C3E34464DC0DDBD587B4030107A5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsReceivable_20B2C3E34464DC0DDBD587B4030107A5" xlink:to="lab_us-gaap_OperatingLeasesFutureMinimumPaymentsReceivable_20B2C3E34464DC0DDBD587B4030107A5" xlink:type="arc" />
    <link:label id="lab_amgn_RentalExpenseOnOperatingLeases_C38656BD2DA1A08254F887B403024275_terseLabel_en-US" xlink:label="lab_amgn_RentalExpenseOnOperatingLeases_C38656BD2DA1A08254F887B403024275" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Rental expense on operating leases</link:label>
    <link:label id="lab_amgn_RentalExpenseOnOperatingLeases_C38656BD2DA1A08254F887B403024275_label_en-US" xlink:label="lab_amgn_RentalExpenseOnOperatingLeases_C38656BD2DA1A08254F887B403024275" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Rental Expense On Operating Leases</link:label>
    <link:label id="lab_amgn_RentalExpenseOnOperatingLeases_C38656BD2DA1A08254F887B403024275_documentation_en-US" xlink:label="lab_amgn_RentalExpenseOnOperatingLeases_C38656BD2DA1A08254F887B403024275" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Rental expense incurred for assets leased under operating leases including furniture and equipment included in operating expenses.</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_RentalExpenseOnOperatingLeases" xlink:label="loc_amgn_RentalExpenseOnOperatingLeases_C38656BD2DA1A08254F887B403024275" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_RentalExpenseOnOperatingLeases_C38656BD2DA1A08254F887B403024275" xlink:to="lab_amgn_RentalExpenseOnOperatingLeases_C38656BD2DA1A08254F887B403024275" xlink:type="arc" />
    <link:label id="lab_us-gaap_NonoperatingIncomeExpenseMember_4FF10E2227DAB892EC826DE05BC4EC35_terseLabel_en-US" xlink:label="lab_us-gaap_NonoperatingIncomeExpenseMember_4FF10E2227DAB892EC826DE05BC4EC35" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Nonoperating Income (Expense) [Member]</link:label>
    <link:label id="lab_us-gaap_NonoperatingIncomeExpenseMember_4FF10E2227DAB892EC826DE05BC4EC35_label_en-US" xlink:label="lab_us-gaap_NonoperatingIncomeExpenseMember_4FF10E2227DAB892EC826DE05BC4EC35" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Nonoperating Income (Expense) [Member]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NonoperatingIncomeExpenseMember" xlink:label="loc_us-gaap_NonoperatingIncomeExpenseMember_4FF10E2227DAB892EC826DE05BC4EC35" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseMember_4FF10E2227DAB892EC826DE05BC4EC35" xlink:to="lab_us-gaap_NonoperatingIncomeExpenseMember_4FF10E2227DAB892EC826DE05BC4EC35" xlink:type="arc" />
    <link:label id="lab_us-gaap_DebtSecuritiesPayableMember_6195DCA845A893A73AF66DE05BC5400D_terseLabel_en-US" xlink:label="lab_us-gaap_DebtSecuritiesPayableMember_6195DCA845A893A73AF66DE05BC5400D" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Debt Securities Payable [Member]</link:label>
    <link:label id="lab_us-gaap_DebtSecuritiesPayableMember_6195DCA845A893A73AF66DE05BC5400D_label_en-US" xlink:label="lab_us-gaap_DebtSecuritiesPayableMember_6195DCA845A893A73AF66DE05BC5400D" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Securities Payable [Member]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtSecuritiesPayableMember" xlink:label="loc_us-gaap_DebtSecuritiesPayableMember_6195DCA845A893A73AF66DE05BC5400D" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DebtSecuritiesPayableMember_6195DCA845A893A73AF66DE05BC5400D" xlink:to="lab_us-gaap_DebtSecuritiesPayableMember_6195DCA845A893A73AF66DE05BC5400D" xlink:type="arc" />
    <link:label id="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_79750C9FD1FD00466CE76DE05BC60C29_terseLabel_en-US" xlink:label="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_79750C9FD1FD00466CE76DE05BC60C29" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">4.563% notes due 2048 (4.563% 2048 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_79750C9FD1FD00466CE76DE05BC60C29_label_en-US" xlink:label="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_79750C9FD1FD00466CE76DE05BC60C29" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Four Point Five Six Three Percent Notes Due Two Zero Four Eight [Member]</link:label>
    <link:label id="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_79750C9FD1FD00466CE76DE05BC60C29_documentation_en-US" xlink:label="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_79750C9FD1FD00466CE76DE05BC60C29" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Four Point Five Six Three Percent Notes Due Two Zero Four Eight [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember" xlink:label="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_79750C9FD1FD00466CE76DE05BC60C29" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_79750C9FD1FD00466CE76DE05BC60C29" xlink:to="lab_amgn_FourPointFiveSixThreePercentNotesDueTwoZeroFourEightMember_79750C9FD1FD00466CE76DE05BC60C29" xlink:type="arc" />
    <link:label id="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_D53D860A1CCB19645BCA6DE05BC640F5_terseLabel_en-US" xlink:label="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_D53D860A1CCB19645BCA6DE05BC640F5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">4.663% notes due 2051 (4.663% 2051 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_D53D860A1CCB19645BCA6DE05BC640F5_label_en-US" xlink:label="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_D53D860A1CCB19645BCA6DE05BC640F5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Four Point Six Six Three Percent Notes Due Two Zero Five One [Member]</link:label>
    <link:label id="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_D53D860A1CCB19645BCA6DE05BC640F5_documentation_en-US" xlink:label="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_D53D860A1CCB19645BCA6DE05BC640F5" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Four Point Six Six Three Percent Notes Due Two Zero Five One [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember" xlink:label="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_D53D860A1CCB19645BCA6DE05BC640F5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_D53D860A1CCB19645BCA6DE05BC640F5" xlink:to="lab_amgn_FourPointSixSixThreePercentNotesDueTwoZeroFiveOneMember_D53D860A1CCB19645BCA6DE05BC640F5" xlink:type="arc" />
    <link:label id="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6500F47F761866A9BE706DE05BC6F936_terseLabel_en-US" xlink:label="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6500F47F761866A9BE706DE05BC6F936" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">6.375% notes due 2037 (6.375% 2037 Notes) [Member]</link:label>
    <link:label id="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6500F47F761866A9BE706DE05BC6F936_label_en-US" xlink:label="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6500F47F761866A9BE706DE05BC6F936" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Six Point Three Seven Five Percent Notes Due 2037 [Member]</link:label>
    <link:label id="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6500F47F761866A9BE706DE05BC6F936_documentation_en-US" xlink:label="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6500F47F761866A9BE706DE05BC6F936" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Six Point Three Seven Five Percent Notes Due 2037 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_SixPointThreeSevenFivePercentNotesDue2037Member" xlink:label="loc_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6500F47F761866A9BE706DE05BC6F936" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6500F47F761866A9BE706DE05BC6F936" xlink:to="lab_amgn_SixPointThreeSevenFivePercentNotesDue2037Member_6500F47F761866A9BE706DE05BC6F936" xlink:type="arc" />
    <link:label id="lab_amgn_SixPointNineZeroPercentNotesDue2038Member_90339A9A77D24B3C5D526DE05BC6E9FE_terseLabel_en-US" xlink:label="lab_amgn_SixPointNineZeroPercentNotesDue2038Member_90339A9A77D24B3C5D526DE05BC6E9FE" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">6.90% notes due 2038 (6.90% 2038 Notes) [Member]</link:label>
    <link:label id="lab_amgn_SixPointNineZeroPercentNotesDue2038Member_90339A9A77D24B3C5D526DE05BC6E9FE_label_en-US" xlink:label="lab_amgn_SixPointNineZeroPercentNotesDue2038Member_90339A9A77D24B3C5D526DE05BC6E9FE" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Six Point Nine Zero Percent Notes Due 2038 [Member]</link:label>
    <link:label id="lab_amgn_SixPointNineZeroPercentNotesDue2038Member_90339A9A77D24B3C5D526DE05BC6E9FE_documentation_en-US" xlink:label="lab_amgn_SixPointNineZeroPercentNotesDue2038Member_90339A9A77D24B3C5D526DE05BC6E9FE" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Six Point Nine Zero Percent Notes Due 2038 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_SixPointNineZeroPercentNotesDue2038Member" xlink:label="loc_amgn_SixPointNineZeroPercentNotesDue2038Member_90339A9A77D24B3C5D526DE05BC6E9FE" xlink:type="locator" />
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    <link:label id="lab_amgn_SixPointFourZeroPercentNotesDue2039Member_19A349478A798DE14A4A6DE05BC68C93_terseLabel_en-US" xlink:label="lab_amgn_SixPointFourZeroPercentNotesDue2039Member_19A349478A798DE14A4A6DE05BC68C93" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">6.40% notes due 2039 (6.40% 2039 Notes) [Member]</link:label>
    <link:label id="lab_amgn_SixPointFourZeroPercentNotesDue2039Member_19A349478A798DE14A4A6DE05BC68C93_label_en-US" xlink:label="lab_amgn_SixPointFourZeroPercentNotesDue2039Member_19A349478A798DE14A4A6DE05BC68C93" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Six Point Four Zero Percent Notes Due 2039 [Member]</link:label>
    <link:label id="lab_amgn_SixPointFourZeroPercentNotesDue2039Member_19A349478A798DE14A4A6DE05BC68C93_documentation_en-US" xlink:label="lab_amgn_SixPointFourZeroPercentNotesDue2039Member_19A349478A798DE14A4A6DE05BC68C93" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Six Point Four Zero Percent Notes Due 2039 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_SixPointFourZeroPercentNotesDue2039Member" xlink:label="loc_amgn_SixPointFourZeroPercentNotesDue2039Member_19A349478A798DE14A4A6DE05BC68C93" xlink:type="locator" />
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    <link:label id="lab_amgn_FivePointSevenFivePercentNotesDue2040Member_CE6739557E93122872F56DE05BC73E72_terseLabel_en-US" xlink:label="lab_amgn_FivePointSevenFivePercentNotesDue2040Member_CE6739557E93122872F56DE05BC73E72" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">5.75% notes due 2040 (5.75% 2040 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointSevenFivePercentNotesDue2040Member_CE6739557E93122872F56DE05BC73E72_label_en-US" xlink:label="lab_amgn_FivePointSevenFivePercentNotesDue2040Member_CE6739557E93122872F56DE05BC73E72" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Five Point Seven Five Percent Notes Due 2040 [Member]</link:label>
    <link:label id="lab_amgn_FivePointSevenFivePercentNotesDue2040Member_CE6739557E93122872F56DE05BC73E72_documentation_en-US" xlink:label="lab_amgn_FivePointSevenFivePercentNotesDue2040Member_CE6739557E93122872F56DE05BC73E72" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Five Point Seven Five Percent Notes Due 2040 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FivePointSevenFivePercentNotesDue2040Member" xlink:label="loc_amgn_FivePointSevenFivePercentNotesDue2040Member_CE6739557E93122872F56DE05BC73E72" xlink:type="locator" />
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    <link:label id="lab_amgn_FivePointOneFivePercentNotesDue2041Member_0D8151A21E709649350B6DE05BC72BF7_terseLabel_en-US" xlink:label="lab_amgn_FivePointOneFivePercentNotesDue2041Member_0D8151A21E709649350B6DE05BC72BF7" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">5.15% notes due 2041 (5.15% 2041 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointOneFivePercentNotesDue2041Member_0D8151A21E709649350B6DE05BC72BF7_label_en-US" xlink:label="lab_amgn_FivePointOneFivePercentNotesDue2041Member_0D8151A21E709649350B6DE05BC72BF7" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Five Point One Five Percent Notes Due 2041 [Member]</link:label>
    <link:label id="lab_amgn_FivePointOneFivePercentNotesDue2041Member_0D8151A21E709649350B6DE05BC72BF7_documentation_en-US" xlink:label="lab_amgn_FivePointOneFivePercentNotesDue2041Member_0D8151A21E709649350B6DE05BC72BF7" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Five Point One Five Percent Notes Due 2041 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FivePointOneFivePercentNotesDue2041Member" xlink:label="loc_amgn_FivePointOneFivePercentNotesDue2041Member_0D8151A21E709649350B6DE05BC72BF7" xlink:type="locator" />
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    <link:label id="lab_amgn_FivePointSixFivePercentNotesDue2042Member_E137FCAFD62E68B49FE46DE05BC7511C_terseLabel_en-US" xlink:label="lab_amgn_FivePointSixFivePercentNotesDue2042Member_E137FCAFD62E68B49FE46DE05BC7511C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">5.65% notes due 2042 (5.65% 2042 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointSixFivePercentNotesDue2042Member_E137FCAFD62E68B49FE46DE05BC7511C_label_en-US" xlink:label="lab_amgn_FivePointSixFivePercentNotesDue2042Member_E137FCAFD62E68B49FE46DE05BC7511C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Five Point Six Five Percent Notes Due 2042 [Member]</link:label>
    <link:label id="lab_amgn_FivePointSixFivePercentNotesDue2042Member_E137FCAFD62E68B49FE46DE05BC7511C_documentation_en-US" xlink:label="lab_amgn_FivePointSixFivePercentNotesDue2042Member_E137FCAFD62E68B49FE46DE05BC7511C" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Five Point Six Five Percent Notes Due 2042 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FivePointSixFivePercentNotesDue2042Member" xlink:label="loc_amgn_FivePointSixFivePercentNotesDue2042Member_E137FCAFD62E68B49FE46DE05BC7511C" xlink:type="locator" />
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    <link:label id="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_9C19F27A2612C4D3717E6DE05BC74E08_terseLabel_en-US" xlink:label="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_9C19F27A2612C4D3717E6DE05BC74E08" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">5.375% notes due 2043 (5.375% 2043 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_9C19F27A2612C4D3717E6DE05BC74E08_label_en-US" xlink:label="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_9C19F27A2612C4D3717E6DE05BC74E08" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Five Point Three Seven Five Percent Notes Due 2043 [Member]</link:label>
    <link:label id="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_9C19F27A2612C4D3717E6DE05BC74E08_documentation_en-US" xlink:label="lab_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_9C19F27A2612C4D3717E6DE05BC74E08" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Five Point Three Seven Five Percent Notes Due 2043 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FivePointThreeSevenFivePercentNotesDue2043Member" xlink:label="loc_amgn_FivePointThreeSevenFivePercentNotesDue2043Member_9C19F27A2612C4D3717E6DE05BC74E08" xlink:type="locator" />
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    <link:label id="lab_amgn_NewSeniorNotesMember_5361D0FF1661C86135C56DE05BC7ABD1_terseLabel_en-US" xlink:label="lab_amgn_NewSeniorNotesMember_5361D0FF1661C86135C56DE05BC7ABD1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">New senior notes [Member]</link:label>
    <link:label id="lab_amgn_NewSeniorNotesMember_5361D0FF1661C86135C56DE05BC7ABD1_label_en-US" xlink:label="lab_amgn_NewSeniorNotesMember_5361D0FF1661C86135C56DE05BC7ABD1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">New Senior Notes [Member]</link:label>
    <link:label id="lab_amgn_NewSeniorNotesMember_5361D0FF1661C86135C56DE05BC7ABD1_documentation_en-US" xlink:label="lab_amgn_NewSeniorNotesMember_5361D0FF1661C86135C56DE05BC7ABD1" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">New Senior Notes [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_NewSeniorNotesMember" xlink:label="loc_amgn_NewSeniorNotesMember_5361D0FF1661C86135C56DE05BC7ABD1" xlink:type="locator" />
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    <link:label id="lab_us-gaap_DebtConversionConvertedInstrumentAmount1_C873669F7059A052EED36DE05BC8C897_terseLabel_en-US" xlink:label="lab_us-gaap_DebtConversionConvertedInstrumentAmount1_C873669F7059A052EED36DE05BC8C897" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Debt conversion, converted instrument, amount</link:label>
    <link:label id="lab_us-gaap_DebtConversionConvertedInstrumentAmount1_C873669F7059A052EED36DE05BC8C897_label_en-US" xlink:label="lab_us-gaap_DebtConversionConvertedInstrumentAmount1_C873669F7059A052EED36DE05BC8C897" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Conversion, Converted Instrument, Amount</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtConversionConvertedInstrumentAmount1" xlink:label="loc_us-gaap_DebtConversionConvertedInstrumentAmount1_C873669F7059A052EED36DE05BC8C897" xlink:type="locator" />
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    <link:label id="lab_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_449E8BC08C0751F992E46DE05BC84590_label_en-US" xlink:label="lab_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_449E8BC08C0751F992E46DE05BC84590" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_449E8BC08C0751F992E46DE05BC84590" xlink:type="locator" />
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    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_F953AE967E2F8440AB2B6D5BF3A42377" xlink:to="lab_us-gaap_LondonInterbankOfferedRateLIBORMember_F953AE967E2F8440AB2B6D5BF3A42377" xlink:type="arc" />
    <link:label id="lab_us-gaap_NotesPayableOtherPayablesMember_E1171A45934AE5B059206D5BF3A4FB24_terseLabel_en-US" xlink:label="lab_us-gaap_NotesPayableOtherPayablesMember_E1171A45934AE5B059206D5BF3A4FB24" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Notes payable [Member]</link:label>
    <link:label id="lab_us-gaap_NotesPayableOtherPayablesMember_E1171A45934AE5B059206D5BF3A4FB24_label_en-US" xlink:label="lab_us-gaap_NotesPayableOtherPayablesMember_E1171A45934AE5B059206D5BF3A4FB24" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Notes Payable, Other Payables [Member]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NotesPayableOtherPayablesMember" xlink:label="loc_us-gaap_NotesPayableOtherPayablesMember_E1171A45934AE5B059206D5BF3A4FB24" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NotesPayableOtherPayablesMember_E1171A45934AE5B059206D5BF3A4FB24" xlink:to="lab_us-gaap_NotesPayableOtherPayablesMember_E1171A45934AE5B059206D5BF3A4FB24" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointTwoZeroPercentNotesDue2019Member_304B99B31AEC5CD5DD766D5BF3A4C1C1_terseLabel_en-US" xlink:label="lab_amgn_TwoPointTwoZeroPercentNotesDue2019Member_304B99B31AEC5CD5DD766D5BF3A4C1C1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.20% notes due 2019 (2.20% 2019 Notes) [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoZeroPercentNotesDue2019Member_304B99B31AEC5CD5DD766D5BF3A4C1C1_label_en-US" xlink:label="lab_amgn_TwoPointTwoZeroPercentNotesDue2019Member_304B99B31AEC5CD5DD766D5BF3A4C1C1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point Two Zero Percent Notes Due 2019 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointTwoZeroPercentNotesDue2019Member_304B99B31AEC5CD5DD766D5BF3A4C1C1_documentation_en-US" xlink:label="lab_amgn_TwoPointTwoZeroPercentNotesDue2019Member_304B99B31AEC5CD5DD766D5BF3A4C1C1" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point Two Zero Percent Notes Due 2019 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointTwoZeroPercentNotesDue2019Member" xlink:label="loc_amgn_TwoPointTwoZeroPercentNotesDue2019Member_304B99B31AEC5CD5DD766D5BF3A4C1C1" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointTwoZeroPercentNotesDue2019Member_304B99B31AEC5CD5DD766D5BF3A4C1C1" xlink:to="lab_amgn_TwoPointTwoZeroPercentNotesDue2019Member_304B99B31AEC5CD5DD766D5BF3A4C1C1" xlink:type="arc" />
    <link:label id="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_9EF802508CE20AE614F36D5BF3A41F1F_terseLabel_en-US" xlink:label="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_9EF802508CE20AE614F36D5BF3A41F1F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">3.45% notes due 2020 (3.45% 2020 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_9EF802508CE20AE614F36D5BF3A41F1F_label_en-US" xlink:label="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_9EF802508CE20AE614F36D5BF3A41F1F" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Three Point Four Five Percent Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_9EF802508CE20AE614F36D5BF3A41F1F_documentation_en-US" xlink:label="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_9EF802508CE20AE614F36D5BF3A41F1F" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Three Point Four Five Percent Notes Due 2020 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_ThreePointFourFivePercentNotesDue2020Member" xlink:label="loc_amgn_ThreePointFourFivePercentNotesDue2020Member_9EF802508CE20AE614F36D5BF3A41F1F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointFourFivePercentNotesDue2020Member_9EF802508CE20AE614F36D5BF3A41F1F" xlink:to="lab_amgn_ThreePointFourFivePercentNotesDue2020Member_9EF802508CE20AE614F36D5BF3A41F1F" xlink:type="arc" />
    <link:label id="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_E7A4A4DB4938685FE2C16D5BF3A4FE29_terseLabel_en-US" xlink:label="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_E7A4A4DB4938685FE2C16D5BF3A4FE29" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">4.10% notes due 2021 (4.10% 2021 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_E7A4A4DB4938685FE2C16D5BF3A4FE29_label_en-US" xlink:label="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_E7A4A4DB4938685FE2C16D5BF3A4FE29" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Four Point One Zero Percent Notes Due 2021 [Member]</link:label>
    <link:label id="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_E7A4A4DB4938685FE2C16D5BF3A4FE29_documentation_en-US" xlink:label="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_E7A4A4DB4938685FE2C16D5BF3A4FE29" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Four Point One Zero Percent Notes Due 2021 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FourPointOneZeroPercentNotesDue2021Member" xlink:label="loc_amgn_FourPointOneZeroPercentNotesDue2021Member_E7A4A4DB4938685FE2C16D5BF3A4FE29" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointOneZeroPercentNotesDue2021Member_E7A4A4DB4938685FE2C16D5BF3A4FE29" xlink:to="lab_amgn_FourPointOneZeroPercentNotesDue2021Member_E7A4A4DB4938685FE2C16D5BF3A4FE29" xlink:type="arc" />
    <link:label id="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_5E036B7AEFD50B6319546D5BF3A4B845_terseLabel_en-US" xlink:label="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_5E036B7AEFD50B6319546D5BF3A4B845" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">3.875% notes due 2021 (3.875% 2021 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_5E036B7AEFD50B6319546D5BF3A4B845_label_en-US" xlink:label="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_5E036B7AEFD50B6319546D5BF3A4B845" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Three Point Eight Seven Five Percent Notes Due 2021 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_5E036B7AEFD50B6319546D5BF3A4B845_documentation_en-US" xlink:label="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_5E036B7AEFD50B6319546D5BF3A4B845" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Three Point Eight Seven Five Percent Notes Due 2021 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_ThreePointEightSevenFivePercentNotesDue2021Member" xlink:label="loc_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_5E036B7AEFD50B6319546D5BF3A4B845" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_5E036B7AEFD50B6319546D5BF3A4B845" xlink:to="lab_amgn_ThreePointEightSevenFivePercentNotesDue2021Member_5E036B7AEFD50B6319546D5BF3A4B845" xlink:type="arc" />
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_C56D6D5B6A302B90E3ED6D5BF3A43FA6_terseLabel_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_C56D6D5B6A302B90E3ED6D5BF3A43FA6" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">3.625% notes due 2022 (3.625% 2022 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_C56D6D5B6A302B90E3ED6D5BF3A43FA6_label_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_C56D6D5B6A302B90E3ED6D5BF3A43FA6" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Three Point Six Two Five Percent Notes Due 2022 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_C56D6D5B6A302B90E3ED6D5BF3A43FA6_documentation_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_C56D6D5B6A302B90E3ED6D5BF3A43FA6" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Three Point Six Two Five Percent Notes Due 2022 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_ThreePointSixTwoFivePercentNotesDue2022Member" xlink:label="loc_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_C56D6D5B6A302B90E3ED6D5BF3A43FA6" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_C56D6D5B6A302B90E3ED6D5BF3A43FA6" xlink:to="lab_amgn_ThreePointSixTwoFivePercentNotesDue2022Member_C56D6D5B6A302B90E3ED6D5BF3A43FA6" xlink:type="arc" />
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_91F3A1B47765BDAFD4EA6D5BF3A49395_terseLabel_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_91F3A1B47765BDAFD4EA6D5BF3A49395" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">3.625% notes due 2024 (3.625% 2024 Notes) [Member]</link:label>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_91F3A1B47765BDAFD4EA6D5BF3A49395_label_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_91F3A1B47765BDAFD4EA6D5BF3A49395" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Three Point Six Two Five Percent Notes Due 2024 [Member]</link:label>
    <link:label id="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_91F3A1B47765BDAFD4EA6D5BF3A49395_documentation_en-US" xlink:label="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_91F3A1B47765BDAFD4EA6D5BF3A49395" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Three Point Six Two Five Percent Notes Due 2024 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_ThreePointSixTwoFivePercentNotesDue2024Member" xlink:label="loc_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_91F3A1B47765BDAFD4EA6D5BF3A49395" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_91F3A1B47765BDAFD4EA6D5BF3A49395" xlink:to="lab_amgn_ThreePointSixTwoFivePercentNotesDue2024Member_91F3A1B47765BDAFD4EA6D5BF3A49395" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_D874438154050C57195F6D5BF3A40F53_verboseLabel_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_D874438154050C57195F6D5BF3A40F53" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">2.125% 2019 euro Notes [Member]</link:label>
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_D874438154050C57195F6D5BF3A40F53_label_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_D874438154050C57195F6D5BF3A40F53" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Two Point One Two Five Percent Euro Notes Due 2019 [Member]</link:label>
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_D874438154050C57195F6D5BF3A40F53_documentation_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_D874438154050C57195F6D5BF3A40F53" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Two Point One Two Five Percent Euro Notes Due 2019 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member" xlink:label="loc_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_D874438154050C57195F6D5BF3A40F53" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_D874438154050C57195F6D5BF3A40F53" xlink:to="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_D874438154050C57195F6D5BF3A40F53" xlink:type="arc" />
    <link:label id="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_C5ED6B4C7E34A574B9846D5BF3A5A46E_verboseLabel_en-US" xlink:label="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_C5ED6B4C7E34A574B9846D5BF3A5A46E" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">5.50% 2026 pound sterling Notes [Member]</link:label>
    <link:label id="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_C5ED6B4C7E34A574B9846D5BF3A5A46E_label_en-US" xlink:label="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_C5ED6B4C7E34A574B9846D5BF3A5A46E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Five Point Five Zero Percent Pound Sterling Notes Due 2026 [Member]</link:label>
    <link:label id="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_C5ED6B4C7E34A574B9846D5BF3A5A46E_documentation_en-US" xlink:label="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_C5ED6B4C7E34A574B9846D5BF3A5A46E" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Five Point Five Zero Percent Pound Sterling Notes Due 2026 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" xlink:label="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_C5ED6B4C7E34A574B9846D5BF3A5A46E" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_C5ED6B4C7E34A574B9846D5BF3A5A46E" xlink:to="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_C5ED6B4C7E34A574B9846D5BF3A5A46E" xlink:type="arc" />
    <link:label id="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_CD83BD28389DA6CACBBD6D5BF3A5F44A_verboseLabel_en-US" xlink:label="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_CD83BD28389DA6CACBBD6D5BF3A5F44A" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">4.00% 2029 pound sterling Notes [Member]</link:label>
    <link:label id="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_CD83BD28389DA6CACBBD6D5BF3A5F44A_label_en-US" xlink:label="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_CD83BD28389DA6CACBBD6D5BF3A5F44A" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Four Percent Pound Sterling Notes Due 2029 [Member]</link:label>
    <link:label id="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_CD83BD28389DA6CACBBD6D5BF3A5F44A_documentation_en-US" xlink:label="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_CD83BD28389DA6CACBBD6D5BF3A5F44A" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Four Percent Pound Sterling Notes Due 2029 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FourPercentPoundSterlingNotesDue2029Member" xlink:label="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_CD83BD28389DA6CACBBD6D5BF3A5F44A" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_CD83BD28389DA6CACBBD6D5BF3A5F44A" xlink:to="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_CD83BD28389DA6CACBBD6D5BF3A5F44A" xlink:type="arc" />
    <link:label id="lab_us-gaap_DerivativeBasisSpreadOnVariableRate_25B0915E451F1751F9636D5BF3A52DD7_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativeBasisSpreadOnVariableRate_25B0915E451F1751F9636D5BF3A52DD7" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Derivative, effective interest rate</link:label>
    <link:label id="lab_us-gaap_DerivativeBasisSpreadOnVariableRate_25B0915E451F1751F9636D5BF3A52DD7_label_en-US" xlink:label="lab_us-gaap_DerivativeBasisSpreadOnVariableRate_25B0915E451F1751F9636D5BF3A52DD7" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Derivative, Basis Spread on Variable Rate</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeBasisSpreadOnVariableRate" xlink:label="loc_us-gaap_DerivativeBasisSpreadOnVariableRate_25B0915E451F1751F9636D5BF3A52DD7" xlink:type="locator" />
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    <link:label id="lab_invest_DerivativeNotionalAmount_CCCB25C96626BD45C2286D5BF3A5606F_terseLabel_en-US" xlink:label="lab_invest_DerivativeNotionalAmount_CCCB25C96626BD45C2286D5BF3A5606F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Notional amount</link:label>
    <link:loc xlink:href="http://xbrl.sec.gov/invest/2013/invest-2013-01-31.xsd#invest_DerivativeNotionalAmount" xlink:label="loc_invest_DerivativeNotionalAmount_CCCB25C96626BD45C2286D5BF3A5606F" xlink:type="locator" />
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    <link:label id="lab_us-gaap_PropertyPlantAndEquipmentUsefulLife_7D34E82ECF8A18EAEF796BF2ACDDB1E1_terseLabel_en-US" xlink:label="lab_us-gaap_PropertyPlantAndEquipmentUsefulLife_7D34E82ECF8A18EAEF796BF2ACDDB1E1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Useful life (in years)</link:label>
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    <link:label id="lab_us-gaap_DerivativeFixedInterestRate_6B180E2DD1F204B18B59FF98F66D4419_label_en-US" xlink:label="lab_us-gaap_DerivativeFixedInterestRate_6B180E2DD1F204B18B59FF98F66D4419" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Derivative, Fixed Interest Rate</link:label>
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    <link:label id="lab_us-gaap_GrossProfit_2A561642209F3A0039FCC8062DC7CB53_label_en-US" xlink:label="lab_us-gaap_GrossProfit_2A561642209F3A0039FCC8062DC7CB53" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Gross Profit</link:label>
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    <link:label id="lab_us-gaap_EarningsPerShareAbstract_418903C812F797C3ACF6C8062DC7E5BE_terseLabel_en-US" xlink:label="lab_us-gaap_EarningsPerShareAbstract_418903C812F797C3ACF6C8062DC7E5BE" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">(Loss) earnings per share:</link:label>
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    <link:label id="lab_us-gaap_StatementOfCashFlowsAbstract_36D6E39F4A332A24DAAC661AA308F062_label_en-US" xlink:label="lab_us-gaap_StatementOfCashFlowsAbstract_36D6E39F4A332A24DAAC661AA308F062" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Statement of Cash Flows [Abstract]</link:label>
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    <link:label id="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_A8FA1E6EB45D44F2900B661AA308E88C_verboseLabel_en-US" xlink:label="lab_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_A8FA1E6EB45D44F2900B661AA308E88C" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Cash flows from operating activities:</link:label>
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    <link:label id="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_0A292C3E3EB6301519D2661AA25FE69A_terseLabel_en-US" xlink:label="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_0A292C3E3EB6301519D2661AA25FE69A" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Aggregate intrinsic value, unexercised</link:label>
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    <link:label id="lab_us-gaap_ConsolidationPolicyTextBlock_B1C035B44D18BA6A58C4FF98F608C945_verboseLabel_en-US" xlink:label="lab_us-gaap_ConsolidationPolicyTextBlock_B1C035B44D18BA6A58C4FF98F608C945" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Principles of consolidation</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock_B1C035B44D18BA6A58C4FF98F608C945" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ConsolidationPolicyTextBlock_B1C035B44D18BA6A58C4FF98F608C945" xlink:to="lab_us-gaap_ConsolidationPolicyTextBlock_B1C035B44D18BA6A58C4FF98F608C945" xlink:type="arc" />
    <link:label id="lab_us-gaap_UseOfEstimates_8E55D8D0EAC85F638298FF98F608E1EE_verboseLabel_en-US" xlink:label="lab_us-gaap_UseOfEstimates_8E55D8D0EAC85F638298FF98F608E1EE" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Use of estimates</link:label>
    <link:label id="lab_us-gaap_UseOfEstimates_8E55D8D0EAC85F638298FF98F608E1EE_label_en-US" xlink:label="lab_us-gaap_UseOfEstimates_8E55D8D0EAC85F638298FF98F608E1EE" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Use of Estimates, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_UseOfEstimates" xlink:label="loc_us-gaap_UseOfEstimates_8E55D8D0EAC85F638298FF98F608E1EE" xlink:type="locator" />
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    <link:label id="lab_us-gaap_RevenueRecognitionSalesOfGoods_4F512DFA5D6EDE5A1F8DFF98F6088AC3_terseLabel_en-US" xlink:label="lab_us-gaap_RevenueRecognitionSalesOfGoods_4F512DFA5D6EDE5A1F8DFF98F6088AC3" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Product sales</link:label>
    <link:label id="lab_us-gaap_RevenueRecognitionSalesOfGoods_4F512DFA5D6EDE5A1F8DFF98F6088AC3_label_en-US" xlink:label="lab_us-gaap_RevenueRecognitionSalesOfGoods_4F512DFA5D6EDE5A1F8DFF98F6088AC3" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Revenue Recognition, Sales of Goods [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RevenueRecognitionSalesOfGoods" xlink:label="loc_us-gaap_RevenueRecognitionSalesOfGoods_4F512DFA5D6EDE5A1F8DFF98F6088AC3" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_RevenueRecognitionSalesOfGoods_4F512DFA5D6EDE5A1F8DFF98F6088AC3" xlink:to="lab_us-gaap_RevenueRecognitionSalesOfGoods_4F512DFA5D6EDE5A1F8DFF98F6088AC3" xlink:type="arc" />
    <link:label id="lab_amgn_OtherRevenuesPolicyTextBlock_456F1338C0214FC5E2A2FF98F6083929_terseLabel_en-US" xlink:label="lab_amgn_OtherRevenuesPolicyTextBlock_456F1338C0214FC5E2A2FF98F6083929" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other revenues</link:label>
    <link:label id="lab_amgn_OtherRevenuesPolicyTextBlock_456F1338C0214FC5E2A2FF98F6083929_label_en-US" xlink:label="lab_amgn_OtherRevenuesPolicyTextBlock_456F1338C0214FC5E2A2FF98F6083929" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Other Revenues [Policy Text Block]</link:label>
    <link:label id="lab_amgn_OtherRevenuesPolicyTextBlock_456F1338C0214FC5E2A2FF98F6083929_documentation_en-US" xlink:label="lab_amgn_OtherRevenuesPolicyTextBlock_456F1338C0214FC5E2A2FF98F6083929" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Describes an entity's accounting policy for other revenues.</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_OtherRevenuesPolicyTextBlock" xlink:label="loc_amgn_OtherRevenuesPolicyTextBlock_456F1338C0214FC5E2A2FF98F6083929" xlink:type="locator" />
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    <link:label id="lab_us-gaap_RevenueRecognitionMultipleElementArrangements_6610639982540F011207FF98F6088C3E_terseLabel_en-US" xlink:label="lab_us-gaap_RevenueRecognitionMultipleElementArrangements_6610639982540F011207FF98F6088C3E" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Multiple-deliverable revenue arrangements</link:label>
    <link:label id="lab_us-gaap_RevenueRecognitionMultipleElementArrangements_6610639982540F011207FF98F6088C3E_label_en-US" xlink:label="lab_us-gaap_RevenueRecognitionMultipleElementArrangements_6610639982540F011207FF98F6088C3E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Revenue Recognition, Multiple-deliverable Arrangements, Description [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RevenueRecognitionMultipleElementArrangements" xlink:label="loc_us-gaap_RevenueRecognitionMultipleElementArrangements_6610639982540F011207FF98F6088C3E" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ResearchAndDevelopmentExpensePolicy_9A22E2BD9EA09785D554FF98F6087CE4_terseLabel_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentExpensePolicy_9A22E2BD9EA09785D554FF98F6087CE4" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Research and development costs</link:label>
    <link:label id="lab_us-gaap_ResearchAndDevelopmentExpensePolicy_9A22E2BD9EA09785D554FF98F6087CE4_label_en-US" xlink:label="lab_us-gaap_ResearchAndDevelopmentExpensePolicy_9A22E2BD9EA09785D554FF98F6087CE4" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Research and Development Expense, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_9A22E2BD9EA09785D554FF98F6087CE4" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_9A22E2BD9EA09785D554FF98F6087CE4" xlink:to="lab_us-gaap_ResearchAndDevelopmentExpensePolicy_9A22E2BD9EA09785D554FF98F6087CE4" xlink:type="arc" />
    <link:label id="lab_us-gaap_SellingGeneralAndAdministrativeExpensesPolicyTextBlock_76D0EA6ECBF13BCA6D0BFF98F609868B_terseLabel_en-US" xlink:label="lab_us-gaap_SellingGeneralAndAdministrativeExpensesPolicyTextBlock_76D0EA6ECBF13BCA6D0BFF98F609868B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Selling, general and administrative costs</link:label>
    <link:label id="lab_us-gaap_SellingGeneralAndAdministrativeExpensesPolicyTextBlock_76D0EA6ECBF13BCA6D0BFF98F609868B_label_en-US" xlink:label="lab_us-gaap_SellingGeneralAndAdministrativeExpensesPolicyTextBlock_76D0EA6ECBF13BCA6D0BFF98F609868B" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Selling, General and Administrative Expenses, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesPolicyTextBlock" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesPolicyTextBlock_76D0EA6ECBF13BCA6D0BFF98F609868B" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_SellingGeneralAndAdministrativeExpensesPolicyTextBlock_76D0EA6ECBF13BCA6D0BFF98F609868B" xlink:to="lab_us-gaap_SellingGeneralAndAdministrativeExpensesPolicyTextBlock_76D0EA6ECBF13BCA6D0BFF98F609868B" xlink:type="arc" />
    <link:label id="lab_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_DF1D406C1F9A22BFC003FF98F6093998_terseLabel_en-US" xlink:label="lab_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_DF1D406C1F9A22BFC003FF98F6093998" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Stock-based compensation</link:label>
    <link:label id="lab_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_DF1D406C1F9A22BFC003FF98F6093998_label_en-US" xlink:label="lab_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_DF1D406C1F9A22BFC003FF98F6093998" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Share-based Compensation, Option and Incentive Plans Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_DF1D406C1F9A22BFC003FF98F6093998" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_DF1D406C1F9A22BFC003FF98F6093998" xlink:to="lab_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_DF1D406C1F9A22BFC003FF98F6093998" xlink:type="arc" />
    <link:label id="lab_us-gaap_IncomeTaxPolicyTextBlock_0B9E1B9A0833F799D292FF98F609F27C_terseLabel_en-US" xlink:label="lab_us-gaap_IncomeTaxPolicyTextBlock_0B9E1B9A0833F799D292FF98F609F27C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Income taxes</link:label>
    <link:label id="lab_us-gaap_IncomeTaxPolicyTextBlock_0B9E1B9A0833F799D292FF98F609F27C_label_en-US" xlink:label="lab_us-gaap_IncomeTaxPolicyTextBlock_0B9E1B9A0833F799D292FF98F609F27C" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Income Tax, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxPolicyTextBlock" xlink:label="loc_us-gaap_IncomeTaxPolicyTextBlock_0B9E1B9A0833F799D292FF98F609F27C" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_IncomeTaxPolicyTextBlock_0B9E1B9A0833F799D292FF98F609F27C" xlink:to="lab_us-gaap_IncomeTaxPolicyTextBlock_0B9E1B9A0833F799D292FF98F609F27C" xlink:type="arc" />
    <link:label id="lab_us-gaap_BusinessCombinationsPolicy_E17B76AE8E3A7A4BB9F4FF98F6090CCE_terseLabel_en-US" xlink:label="lab_us-gaap_BusinessCombinationsPolicy_E17B76AE8E3A7A4BB9F4FF98F6090CCE" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Business combinations</link:label>
    <link:label id="lab_us-gaap_BusinessCombinationsPolicy_E17B76AE8E3A7A4BB9F4FF98F6090CCE_label_en-US" xlink:label="lab_us-gaap_BusinessCombinationsPolicy_E17B76AE8E3A7A4BB9F4FF98F6090CCE" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Business Combinations Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationsPolicy" xlink:label="loc_us-gaap_BusinessCombinationsPolicy_E17B76AE8E3A7A4BB9F4FF98F6090CCE" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_BusinessCombinationsPolicy_E17B76AE8E3A7A4BB9F4FF98F6090CCE" xlink:to="lab_us-gaap_BusinessCombinationsPolicy_E17B76AE8E3A7A4BB9F4FF98F6090CCE" xlink:type="arc" />
    <link:label id="lab_us-gaap_CashAndCashEquivalentsPolicyTextBlock_0F8B2351D672CFB5C70FFF98F609B5C2_terseLabel_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsPolicyTextBlock_0F8B2351D672CFB5C70FFF98F609B5C2" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Cash equivalents</link:label>
    <link:label id="lab_us-gaap_CashAndCashEquivalentsPolicyTextBlock_0F8B2351D672CFB5C70FFF98F609B5C2_label_en-US" xlink:label="lab_us-gaap_CashAndCashEquivalentsPolicyTextBlock_0F8B2351D672CFB5C70FFF98F609B5C2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Cash and Cash Equivalents, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAndCashEquivalentsPolicyTextBlock" xlink:label="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_0F8B2351D672CFB5C70FFF98F609B5C2" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_0F8B2351D672CFB5C70FFF98F609B5C2" xlink:to="lab_us-gaap_CashAndCashEquivalentsPolicyTextBlock_0F8B2351D672CFB5C70FFF98F609B5C2" xlink:type="arc" />
    <link:label id="lab_us-gaap_InvestmentPolicyTextBlock_61233648BAF596EC56E5FF98F609BFB3_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentPolicyTextBlock_61233648BAF596EC56E5FF98F609BFB3" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Available-for-sale investments</link:label>
    <link:label id="lab_us-gaap_InvestmentPolicyTextBlock_61233648BAF596EC56E5FF98F609BFB3_label_en-US" xlink:label="lab_us-gaap_InvestmentPolicyTextBlock_61233648BAF596EC56E5FF98F609BFB3" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Investment, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InvestmentPolicyTextBlock" xlink:label="loc_us-gaap_InvestmentPolicyTextBlock_61233648BAF596EC56E5FF98F609BFB3" xlink:type="locator" />
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    <link:label id="lab_us-gaap_InventoryPolicyTextBlock_094C7A6040EA362D3EA8FF98F6095255_terseLabel_en-US" xlink:label="lab_us-gaap_InventoryPolicyTextBlock_094C7A6040EA362D3EA8FF98F6095255" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Inventories</link:label>
    <link:label id="lab_us-gaap_InventoryPolicyTextBlock_094C7A6040EA362D3EA8FF98F6095255_label_en-US" xlink:label="lab_us-gaap_InventoryPolicyTextBlock_094C7A6040EA362D3EA8FF98F6095255" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Inventory, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryPolicyTextBlock" xlink:label="loc_us-gaap_InventoryPolicyTextBlock_094C7A6040EA362D3EA8FF98F6095255" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InventoryPolicyTextBlock_094C7A6040EA362D3EA8FF98F6095255" xlink:to="lab_us-gaap_InventoryPolicyTextBlock_094C7A6040EA362D3EA8FF98F6095255" xlink:type="arc" />
    <link:label id="lab_us-gaap_DerivativesPolicyTextBlock_0D80923340499661C81EFF98F609E52A_terseLabel_en-US" xlink:label="lab_us-gaap_DerivativesPolicyTextBlock_0D80923340499661C81EFF98F609E52A" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Derivatives</link:label>
    <link:label id="lab_us-gaap_DerivativesPolicyTextBlock_0D80923340499661C81EFF98F609E52A_label_en-US" xlink:label="lab_us-gaap_DerivativesPolicyTextBlock_0D80923340499661C81EFF98F609E52A" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Derivatives, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativesPolicyTextBlock" xlink:label="loc_us-gaap_DerivativesPolicyTextBlock_0D80923340499661C81EFF98F609E52A" xlink:type="locator" />
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    <link:label id="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_EEAE67AB1D120AECFFE1FF98F609D5D1_verboseLabel_en-US" xlink:label="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_EEAE67AB1D120AECFFE1FF98F609D5D1" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">Property, plant and equipment, net</link:label>
    <link:label id="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_EEAE67AB1D120AECFFE1FF98F609D5D1_label_en-US" xlink:label="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_EEAE67AB1D120AECFFE1FF98F609D5D1" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Property, Plant and Equipment, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_EEAE67AB1D120AECFFE1FF98F609D5D1" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_EEAE67AB1D120AECFFE1FF98F609D5D1" xlink:to="lab_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_EEAE67AB1D120AECFFE1FF98F609D5D1" xlink:type="arc" />
    <link:label id="lab_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_83290EB09E8D052AEF6DFF98F6095F55_terseLabel_en-US" xlink:label="lab_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_83290EB09E8D052AEF6DFF98F6095F55" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Goodwill and other intangible assets</link:label>
    <link:label id="lab_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_83290EB09E8D052AEF6DFF98F6095F55_label_en-US" xlink:label="lab_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_83290EB09E8D052AEF6DFF98F6095F55" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Goodwill and Intangible Assets, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_83290EB09E8D052AEF6DFF98F6095F55" xlink:type="locator" />
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    <link:label id="lab_us-gaap_CommitmentsAndContingenciesPolicyTextBlock_22A03F88481771169A9EFF98F60964A9_terseLabel_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingenciesPolicyTextBlock_22A03F88481771169A9EFF98F60964A9" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Contingencies</link:label>
    <link:label id="lab_us-gaap_CommitmentsAndContingenciesPolicyTextBlock_22A03F88481771169A9EFF98F60964A9_label_en-US" xlink:label="lab_us-gaap_CommitmentsAndContingenciesPolicyTextBlock_22A03F88481771169A9EFF98F60964A9" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Commitments and Contingencies, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommitmentsAndContingenciesPolicyTextBlock" xlink:label="loc_us-gaap_CommitmentsAndContingenciesPolicyTextBlock_22A03F88481771169A9EFF98F60964A9" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommitmentsAndContingenciesPolicyTextBlock_22A03F88481771169A9EFF98F60964A9" xlink:to="lab_us-gaap_CommitmentsAndContingenciesPolicyTextBlock_22A03F88481771169A9EFF98F60964A9" xlink:type="arc" />
    <link:label id="lab_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_14ABC726873AAEFEF007FF98F6092ADD_terseLabel_en-US" xlink:label="lab_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_14ABC726873AAEFEF007FF98F6092ADD" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Foreign currency translation</link:label>
    <link:label id="lab_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_14ABC726873AAEFEF007FF98F6092ADD_label_en-US" xlink:label="lab_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_14ABC726873AAEFEF007FF98F6092ADD" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Foreign Currency Transactions and Translations Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock" xlink:label="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_14ABC726873AAEFEF007FF98F6092ADD" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_14ABC726873AAEFEF007FF98F6092ADD" xlink:to="lab_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_14ABC726873AAEFEF007FF98F6092ADD" xlink:type="arc" />
    <link:label id="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_9FD8F4B5270BC8F33FD6FF98F60A006E_terseLabel_en-US" xlink:label="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_9FD8F4B5270BC8F33FD6FF98F60A006E" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Recent accounting pronouncements</link:label>
    <link:label id="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_9FD8F4B5270BC8F33FD6FF98F60A006E_label_en-US" xlink:label="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_9FD8F4B5270BC8F33FD6FF98F60A006E" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">New Accounting Pronouncements, Policy [Policy Text Block]</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_9FD8F4B5270BC8F33FD6FF98F60A006E" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_9FD8F4B5270BC8F33FD6FF98F60A006E" xlink:to="lab_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_9FD8F4B5270BC8F33FD6FF98F60A006E" xlink:type="arc" />
    <link:label id="lab_amgn_SixPointOneFivePercentNotesDue2018Member_D7C7ADBE20E15A48C1178B9033A28CE7_terseLabel_en-US" xlink:label="lab_amgn_SixPointOneFivePercentNotesDue2018Member_D7C7ADBE20E15A48C1178B9033A28CE7" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">6.15% notes due 2018 (6.15% 2018 Notes) [Member]</link:label>
    <link:label id="lab_amgn_SixPointOneFivePercentNotesDue2018Member_D7C7ADBE20E15A48C1178B9033A28CE7_label_en-US" xlink:label="lab_amgn_SixPointOneFivePercentNotesDue2018Member_D7C7ADBE20E15A48C1178B9033A28CE7" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Six Point One Five Percent Notes Due 2018 [Member]</link:label>
    <link:label id="lab_amgn_SixPointOneFivePercentNotesDue2018Member_D7C7ADBE20E15A48C1178B9033A28CE7_documentation_en-US" xlink:label="lab_amgn_SixPointOneFivePercentNotesDue2018Member_D7C7ADBE20E15A48C1178B9033A28CE7" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Six Point One Five Percent Notes Due 2018 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_SixPointOneFivePercentNotesDue2018Member" xlink:label="loc_amgn_SixPointOneFivePercentNotesDue2018Member_D7C7ADBE20E15A48C1178B9033A28CE7" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_SixPointOneFivePercentNotesDue2018Member_D7C7ADBE20E15A48C1178B9033A28CE7" xlink:to="lab_amgn_SixPointOneFivePercentNotesDue2018Member_D7C7ADBE20E15A48C1178B9033A28CE7" xlink:type="arc" />
    <link:label id="lab_amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member_67E8E1F1EEB38F92BB238B9033A2C399_verboseLabel_en-US" xlink:label="lab_amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member_67E8E1F1EEB38F92BB238B9033A2C399" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">4.375% euro-denominated notes due 2018 (4.375% 2018 euro Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member_67E8E1F1EEB38F92BB238B9033A2C399_label_en-US" xlink:label="lab_amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member_67E8E1F1EEB38F92BB238B9033A2C399" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Four Point Three Seven Five Percent Euro Notes Due 2018 [Member]</link:label>
    <link:label id="lab_amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member_67E8E1F1EEB38F92BB238B9033A2C399_documentation_en-US" xlink:label="lab_amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member_67E8E1F1EEB38F92BB238B9033A2C399" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Four Point Three Seven Five Percent Euro Notes Due 2018 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member" xlink:label="loc_amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member_67E8E1F1EEB38F92BB238B9033A2C399" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member_67E8E1F1EEB38F92BB238B9033A2C399" xlink:to="lab_amgn_FourPointThreeSevenFivePercentEuroNotesDue2018Member_67E8E1F1EEB38F92BB238B9033A2C399" xlink:type="arc" />
    <link:label id="lab_amgn_FivePointSevenZeroPercentNotesDue2019Member_452042A2AB448725A1B68B9033A270B5_terseLabel_en-US" xlink:label="lab_amgn_FivePointSevenZeroPercentNotesDue2019Member_452042A2AB448725A1B68B9033A270B5" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">5.70% notes due 2019 (5.70% 2019 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FivePointSevenZeroPercentNotesDue2019Member_452042A2AB448725A1B68B9033A270B5_label_en-US" xlink:label="lab_amgn_FivePointSevenZeroPercentNotesDue2019Member_452042A2AB448725A1B68B9033A270B5" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Five Point Seven Zero Percent Notes Due 2019 [Member]</link:label>
    <link:label id="lab_amgn_FivePointSevenZeroPercentNotesDue2019Member_452042A2AB448725A1B68B9033A270B5_documentation_en-US" xlink:label="lab_amgn_FivePointSevenZeroPercentNotesDue2019Member_452042A2AB448725A1B68B9033A270B5" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Five Point Seven Zero Percent Notes Due 2019 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FivePointSevenZeroPercentNotesDue2019Member" xlink:label="loc_amgn_FivePointSevenZeroPercentNotesDue2019Member_452042A2AB448725A1B68B9033A270B5" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePointSevenZeroPercentNotesDue2019Member_452042A2AB448725A1B68B9033A270B5" xlink:to="lab_amgn_FivePointSevenZeroPercentNotesDue2019Member_452042A2AB448725A1B68B9033A270B5" xlink:type="arc" />
    <link:label id="lab_amgn_FloatingRateNotesDue2019Member_DCEA2AED881360C28BC98B9033A238F2_terseLabel_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2019Member_DCEA2AED881360C28BC98B9033A238F2" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Floating rate notes due 2019 [Member]</link:label>
    <link:label id="lab_amgn_FloatingRateNotesDue2019Member_DCEA2AED881360C28BC98B9033A238F2_label_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2019Member_DCEA2AED881360C28BC98B9033A238F2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Floating Rate Notes Due 2019 [Member]</link:label>
    <link:label id="lab_amgn_FloatingRateNotesDue2019Member_DCEA2AED881360C28BC98B9033A238F2_documentation_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2019Member_DCEA2AED881360C28BC98B9033A238F2" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Floating Rate Notes Due 2019 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FloatingRateNotesDue2019Member" xlink:label="loc_amgn_FloatingRateNotesDue2019Member_DCEA2AED881360C28BC98B9033A238F2" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FloatingRateNotesDue2019Member_DCEA2AED881360C28BC98B9033A238F2" xlink:to="lab_amgn_FloatingRateNotesDue2019Member_DCEA2AED881360C28BC98B9033A238F2" xlink:type="arc" />
    <link:label id="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_1F54ECB775CD33B960688B9033A2927C_terseLabel_en-US" xlink:label="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_1F54ECB775CD33B960688B9033A2927C" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2.125% euro-denominated notes due 2019 (2.125% 2019 euro Notes) [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member" xlink:label="loc_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_1F54ECB775CD33B960688B9033A2927C" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_1F54ECB775CD33B960688B9033A2927C" xlink:to="lab_amgn_TwoPointOneTwoFivePercentEuroNotesDue2019Member_1F54ECB775CD33B960688B9033A2927C" xlink:type="arc" />
    <link:label id="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_DC8833BC8EC408ECBA108B9033A3DDE9_terseLabel_en-US" xlink:label="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_DC8833BC8EC408ECBA108B9033A3DDE9" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">4.50% notes due 2020 (4.50% 2020 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_DC8833BC8EC408ECBA108B9033A3DDE9_label_en-US" xlink:label="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_DC8833BC8EC408ECBA108B9033A3DDE9" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Four Point Five Zero Percent Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_DC8833BC8EC408ECBA108B9033A3DDE9_documentation_en-US" xlink:label="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_DC8833BC8EC408ECBA108B9033A3DDE9" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Four Point Five Zero Percent Notes Due 2020 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FourPointFiveZeroPercentNotesDue2020Member" xlink:label="loc_amgn_FourPointFiveZeroPercentNotesDue2020Member_DC8833BC8EC408ECBA108B9033A3DDE9" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPointFiveZeroPercentNotesDue2020Member_DC8833BC8EC408ECBA108B9033A3DDE9" xlink:to="lab_amgn_FourPointFiveZeroPercentNotesDue2020Member_DC8833BC8EC408ECBA108B9033A3DDE9" xlink:type="arc" />
    <link:label id="lab_amgn_FloatingRateNotesDue2020Member_E261C573835B86B3107E8B9033A3D436_terseLabel_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2020Member_E261C573835B86B3107E8B9033A3D436" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Floating Rate Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_FloatingRateNotesDue2020Member_E261C573835B86B3107E8B9033A3D436_label_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2020Member_E261C573835B86B3107E8B9033A3D436" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Floating Rate Notes Due 2020 [Member]</link:label>
    <link:label id="lab_amgn_FloatingRateNotesDue2020Member_E261C573835B86B3107E8B9033A3D436_documentation_en-US" xlink:label="lab_amgn_FloatingRateNotesDue2020Member_E261C573835B86B3107E8B9033A3D436" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Floating Rate Notes Due 2020 [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FloatingRateNotesDue2020Member" xlink:label="loc_amgn_FloatingRateNotesDue2020Member_E261C573835B86B3107E8B9033A3D436" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FloatingRateNotesDue2020Member_E261C573835B86B3107E8B9033A3D436" xlink:to="lab_amgn_FloatingRateNotesDue2020Member_E261C573835B86B3107E8B9033A3D436" xlink:type="arc" />
    <link:label id="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_AD5BBF6818CF7342A4268B9033A4271F_terseLabel_en-US" xlink:label="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_AD5BBF6818CF7342A4268B9033A4271F" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">5.50% pound-sterling-denominated notes due 2026 (5.50% 2026 pound sterling Notes) [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member" xlink:label="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_AD5BBF6818CF7342A4268B9033A4271F" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_AD5BBF6818CF7342A4268B9033A4271F" xlink:to="lab_amgn_FivePointFiveZeroPercentPoundSterlingNotesDue2026Member_AD5BBF6818CF7342A4268B9033A4271F" xlink:type="arc" />
    <link:label id="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_305801243014336CEFDA8B9033A400FC_terseLabel_en-US" xlink:label="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_305801243014336CEFDA8B9033A400FC" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">4.00% pound-sterling-denominated notes due 2029 (4.00% 2029 pound sterling Notes) [Member]</link:label>
    <link:loc xlink:href="amgn-20171231.xsd#amgn_FourPercentPoundSterlingNotesDue2029Member" xlink:label="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_305801243014336CEFDA8B9033A400FC" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_amgn_FourPercentPoundSterlingNotesDue2029Member_305801243014336CEFDA8B9033A400FC" xlink:to="lab_amgn_FourPercentPoundSterlingNotesDue2029Member_305801243014336CEFDA8B9033A400FC" xlink:type="arc" />
    <link:label id="lab_amgn_FourPointNineFivePercentNotesDue2041Member_16295DC78BDA56B9E32E8B9033A4BAF8_verboseLabel_en-US" xlink:label="lab_amgn_FourPointNineFivePercentNotesDue2041Member_16295DC78BDA56B9E32E8B9033A4BAF8" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:type="resource" xml:lang="en-US">4.95% notes due 2041 (4.95% 2041 Notes) [Member]</link:label>
    <link:label id="lab_amgn_FourPointNineFivePercentNotesDue2041Member_16295DC78BDA56B9E32E8B9033A4BAF8_label_en-US" xlink:label="lab_amgn_FourPointNineFivePercentNotesDue2041Member_16295DC78BDA56B9E32E8B9033A4BAF8" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Four Point Nine Five Percent Notes Due 2041 [Member]</link:label>
    <link:label id="lab_amgn_FourPointNineFivePercentNotesDue2041Member_16295DC78BDA56B9E32E8B9033A4BAF8_documentation_en-US" xlink:label="lab_amgn_FourPointNineFivePercentNotesDue2041Member_16295DC78BDA56B9E32E8B9033A4BAF8" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Four Point Nine Five Percent Notes Due 2041 [Member]</link:label>
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    <link:label id="lab_us-gaap_DebtInstrumentInterestRateEffectivePercentage_727B530DE58E5FE4E3378B9033A4CDE0_terseLabel_en-US" xlink:label="lab_us-gaap_DebtInstrumentInterestRateEffectivePercentage_727B530DE58E5FE4E3378B9033A4CDE0" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Effective interest rate on note</link:label>
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