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Business combinations (Aggregate Consideration Paid) (Details) - Kirin-Amgen, Inc. (K-A) [Member] $ in Millions | 3 Months Ended
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Mar. 31, 2018 USD ($)
Business Acquisition [Line Items] |
Total cash paid to Kirin | $ 780
Fair value of contingent consideration obligation | 45
Loss on settlement of preexisting relationship | (168)
Total consideration transferred to acquire K-A | 657
Fair value of Amgen’s investment in K-A | 825
Total acquisition date fair value | $ 1,482

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