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Consolidated Statements of Income - USD ($)
shares in Millions, $ in Millions
 12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Revenues:      
Total revenues $ 23,747 $ 22,849 $ 22,991
Operating expenses:      
Cost of sales 4,101 4,069 4,162
Research and development 3,737 3,562 3,840
Selling, general and administrative 5,332 4,870 5,062
Other 314 375 133
Total operating expenses 13,484 12,876 13,197
Operating income 10,263 9,973 9,794
Interest expense, net 1,392 1,304 1,260
Interest and other income, net 674 928 629
Income before income taxes 9,545 9,597 9,163
Provision for income taxes 1,151 7,618 1,441
Net income $ 8,394 $ 1,979 $ 7,722
Earnings per share:      
Basic (in usd per share) $ 12.70 $ 2.71 $ 10.32
Diluted (in usd per share) $ 12.62 $ 2.69 $ 10.24
Shares used in the calculation of earnings per share:      
Basic (in shares) 661 731 748
Diluted (in shares) 665 735 754
Product [Member]      
Revenues:      
Product sales $ 22,533 $ 21,795 $ 21,892
Other [Member]      
Revenues:      
Total revenues $ 1,214 $ 1,054 $ 1,099