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Condensed Consolidated Statements of Income - USD ($)
shares in Millions, $ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Revenues:        
Total revenues $ 5,871 $ 6,059 $ 11,428 $ 11,613
Operating expenses:        
Cost of sales 1,012 1,024 2,067 1,968
Research and development 924 869 1,803 1,629
Selling, general and administrative 1,260 1,353 2,414 2,480
Other (3) (19) (6) (22)
Total operating expenses 3,193 3,227 6,278 6,055
Operating income 2,678 2,832 5,150 5,558
Interest expense, net 332 347 675 685
Interest and other income, net 218 162 403 393
Income before income taxes 2,564 2,647 4,878 5,266
Provision for income taxes 385 351 707 659
Net income $ 2,179 $ 2,296 $ 4,171 $ 4,607
Earnings per share:        
Basic (in usd per share) $ 3.59 $ 3.50 $ 6.78 $ 6.76
Diluted (in usd per share) $ 3.57 $ 3.48 $ 6.75 $ 6.73
Shares used in calculation of earnings per share:        
Basic (in shares) 607 656 615 682
Diluted (in shares) 610 660 618 685
Product sales [Member]        
Revenues:        
Product sales $ 5,574 $ 5,679 $ 10,860 $ 11,022
Other revenues [Member]        
Revenues:        
Total revenues $ 297 $ 380 $ 568 $ 591