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Fair value measurement - Narrative (Details) - USD ($) | 12 Months Ended |
--- | --- | ---
Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2015 | Dec. 31, 2011
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Length of time hedged in foreign currency contracts | 3 years |  |  |  |
Aggregate fair value of long-term debt, including current portion | $ 33,700,000,000 | $ 35,000,000,000.0 |  |  |
Carrying value of long-term debt, including current portion | $ 29,903,000,000 | 33,929,000,000 |  |  |
Other operating income (expense) [Member] | IPR&D [Member] |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
IPR&D impairment charge |  | $ 330,000,000 |  |  |
Other operating income (expense) [Member] | AMG 899 [Member] | IPR&D [Member] |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
IPR&D impairment charge |  |  | $ 400,000,000 |  |
Dezima [Member] |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Maximum additional consideration due contingent on certain milestones |  |  |  | $ 1,250,000,000 |
Estimated fair values of contingent consideration obligations |  |  | 110,000,000 | $ 110,000,000 |
Dezima [Member] | AMG 899 [Member] |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Estimated fair values of contingent consideration obligations |  |  | 0 |  |
Dezima [Member] | Other operating income (expense) [Member] | AMG 899 [Member] |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Estimated fair values of contingent consideration obligations |  |  | $ 116,000,000 |  |
Biovex [Member] |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Additional contingent consideration upon achievement of milestones |  |  |  |  | $ 325,000,000
Other government-related and corporate debt securities [Member] |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Investment maturity period | 3 years |  |  |  |

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