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Collaborations - Novartis AG (Details) - USD ($) $ in Millions | 12 Months Ended
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Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Revenues | $ 23,362 | $ 23,747 | $ 22,849
Other revenues [Member] |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Revenues | 1,158 | 1,214 | 1,054
Collaborative Arrangement with Novartis AG [Member] |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Potential future milestone payment | 100 |  |
Collaborative Arrangement with Novartis AG [Member] | Other revenues [Member] |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Revenues |  | 295 |
Collaborative Arrangement with Novartis AG [Member] | Selling, general and administrative [Member] |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Cost paid |  | 44 |
Cost recoveries | 187 |  |
Collaborative Arrangement with Novartis AG [Member] | Research and development [Member] |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Cost recoveries |  |  | $ 124
Collaborative Arrangement with Novartis AG [Member] | Cost of sales [Member] |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Royalties due | $ 115 | $ 43 |

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