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Revenues - Narrative (Details) $ in Millions	3 Months Ended								12 Months Ended
	Dec. 31, 2020 USD ($)	Sep. 30, 2020 USD ($)	Jun. 30, 2020 USD ($)	Mar. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Sep. 30, 2019 USD ($)	Jun. 30, 2019 USD ($)	Mar. 31, 2019 USD ($)	Dec. 31, 2020 USD ($) segment customer	Dec. 31, 2019 USD ($) customer	Dec. 31, 2018 USD ($) customer
Revenue from Contract with Customer [Abstract]
Number of operating segments | segment									1
Revenue from External Customer [Line Items]
Number of major customers (as defined) accounting for more than 10% of total revenue | customer									3	3	3
Major customers (as defined) accounting for more than 10% of gross trade receivables | customer									3	3
Combined trade receivables for all major customers (as defined) as a percentage of net trade receivables	74.00%				73.00%				74.00%	73.00%
Percentage of worldwide gross revenues derived from major customers (as defined) on a combined basis									83.00%
Total product sales									$ 25,424	$ 23,362	$ 23,747
Percentage of net trade receivables due from customers located outside the United States, primarily in Europe	28.00%				27.00%				28.00%	27.00%
US [Member]
Revenue from External Customer [Line Items]
Total product sales									$ 18,496	$ 17,224	18,358
ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									6,928	6,138	5,389
Product sales [Member]
Revenue from External Customer [Line Items]
Total product sales	$ 6,334	$ 6,104	$ 5,908	$ 5,894	$ 5,881	$ 5,463	$ 5,574	$ 5,286	24,240	22,204	22,533
Product sales [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									17,985	16,531	17,429
Product sales [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									6,255	5,673	5,104
Enbrel® (etanercept) [Member]
Revenue from External Customer [Line Items]
Total product sales									4,996	5,226	5,014
Enbrel® (etanercept) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									4,855	5,050	4,807
Enbrel® (etanercept) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									141	176	207
Prolia® (denosumab) [Member]
Revenue from External Customer [Line Items]
Total product sales									2,763	2,672	2,291
Prolia® (denosumab) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									1,830	1,772	1,500
Prolia® (denosumab) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									933	900	791
Neulasta® (pegfilgrastim) [Member]
Revenue from External Customer [Line Items]
Total product sales									2,293	3,221	4,475
Neulasta® (pegfilgrastim) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									2,001	2,814	3,866
Neulasta® (pegfilgrastim) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									292	407	609
Otezla [Member]
Revenue from External Customer [Line Items]
Total product sales									2,195	178	0
Otezla [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									1,790	139	0
Otezla [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									405	39	0
XGEVA® (denosumab) [Member]
Revenue from External Customer [Line Items]
Total product sales									1,899	1,935	1,786
XGEVA® (denosumab) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									1,405	1,457	1,338
XGEVA® (denosumab) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									494	478	448
Aranesp® (darbepoetin alfa) [Member]
Revenue from External Customer [Line Items]
Total product sales									1,568	1,729	1,877
Aranesp® (darbepoetin alfa) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									629	758	942
Aranesp® (darbepoetin alfa) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									939	971	935
Kyprolis [Member]
Revenue from External Customer [Line Items]
Total product sales									1,065	1,044	968
Kyprolis [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									710	654	583
Kyprolis [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									355	390	385
Repatha (evolocumab) [Member]
Revenue from External Customer [Line Items]
Total product sales									887	661	550
Repatha (evolocumab) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									459	376	358
Repatha (evolocumab) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									428	285	192
Other products [Member]
Revenue from External Customer [Line Items]
Total product sales									6,574	5,538	5,572
Other products [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									4,306	3,511	4,035
Other products [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									2,268	2,027	1,537
Other revenues [Member]
Revenue from External Customer [Line Items]
Total product sales									1,184	1,158	1,214
Other revenues [Member] | US [Member]
Revenue from External Customer [Line Items]
Total product sales									511	693	929
Other revenues [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total product sales									673	465	285
AmerisourceBergen Corporation [Member] | Product sales [Member]
Revenue from External Customer [Line Items]
Total product sales									14,743	12,301	12,091
McKesson Corporation [Member] | Product sales [Member]
Revenue from External Customer [Line Items]
Total product sales									13,779	11,795	11,434
Cardinal Health, Inc. [Member] | Product sales [Member]
Revenue from External Customer [Line Items]
Total product sales									$ 7,332	$ 6,538	$ 7,475

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