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Condensed Consolidated Statements of Income - USD ($)
shares in Millions, $ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Revenues:        
Total revenues $ 6,526 $ 6,206 $ 12,427 $ 12,367
Operating expenses:        
Cost of sales 1,637 1,488 3,127 3,001
Research and development 1,082 964 2,049 1,916
Acquired in-process research and development 1,505 0 1,505 0
Selling, general and administrative 1,384 1,295 2,638 2,611
Other 90 136 151 161
Total operating expenses 5,698 3,883 9,470 7,689
Operating income 828 2,323 2,957 4,678
Interest expense, net (281) (296) (566) (642)
Other income, net 11 3 24 14
Income before income taxes 558 2,030 2,415 4,050
Provision for income taxes 94 227 305 422
Net income $ 464 $ 1,803 $ 2,110 $ 3,628
Earnings per share:        
Basic (in usd per share) $ 0.81 $ 3.07 $ 3.67 $ 6.16
Diluted (in usd per share) $ 0.81 $ 3.05 $ 3.65 $ 6.12
Shares used in calculation of earnings per share:        
Basic (in shares) 573 588 575 589
Diluted (in shares) 576 592 578 593
Product sales [Member]        
Revenues:        
Product sales $ 6,114 $ 5,908 $ 11,706 $ 11,802
Other revenues [Member]        
Revenues:        
Total revenues $ 412 $ 298 $ 721 $ 565