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Revenues | 9 Months Ended
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Sep. 30, 2021
Revenue from Contract with Customer [Abstract] |
Revenues | Revenues We operate in one business segment: human therapeutics. Therefore, results of our operations are reported on a consolidated basis for purposes of segment reporting, consistent with internal management reporting. Revenues by product and by geographic area, based on customers’ locations, are presented below. The majority of rest-of-world (ROW) revenues relates to products sold in Europe. Revenues were as follows (in millions):
|  | Three months ended September 30,
|  | 2021 |  | 2020
|  | U.S. |  | ROW |  | Total |  | U.S. |  | ROW |  | Total
Enbrel® (etanercept) |  | $ | 1,263 |  |  | $ | 26 |  |  | $ | 1,289 |  |  | $ | 1,289 |  |  | $ | 36 |  |  | $ | 1,325 |
Prolia® (denosumab) |  | 530 |  |  | 273 |  |  | 803 |  |  | 478 |  |  | 223 |  |  | 701 |
Otezla® (apremilast) |  | 495 |  |  | 114 |  |  | 609 |  |  | 439 |  |  | 99 |  |  | 538 |
XGEVA® (denosumab) |  | 372 |  |  | 145 |  |  | 517 |  |  | 363 |  |  | 118 |  |  | 481 |
Neulasta® (pegfilgrastim) |  | 360 |  |  | 55 |  |  | 415 |  |  | 484 |  |  | 71 |  |  | 555 |
Aranesp® (darbepoetin alfa) |  | 149 |  |  | 247 |  |  | 396 |  |  | 158 |  |  | 226 |  |  | 384 |
Repatha® (evolocumab) |  | 139 |  |  | 133 |  |  | 272 |  |  | 92 |  |  | 113 |  |  | 205 |
KYPROLIS® (carfilzomib) |  | 198 |  |  | 95 |  |  | 293 |  |  | 173 |  |  | 87 |  |  | 260 |
Other products |  | 1,052 |  |  | 674 |  |  | 1,726 |  |  | 1,142 |  |  | 513 |  |  | 1,655 |
Total product sales(1) |  | $ | 4,558 |  |  | $ | 1,762 |  |  | 6,320 |  |  | $ | 4,618 |  |  | $ | 1,486 |  |  | 6,104 |
Other revenues |  |  |  |  |  | 386 |  |  |  |  |  |  | 319 |
Total revenues |  |  |  |  |  | $ | 6,706 |  |  |  |  |  |  | $ | 6,423 |
|  | Nine months ended September 30,
|  | 2021 |  | 2020
|  | U.S. |  | ROW |  | Total |  | U.S. |  | ROW |  | Total
ENBREL |  | $ | 3,270 |  |  | $ | 87 |  |  | $ | 3,357 |  |  | $ | 3,619 |  |  | $ | 105 |  |  | $ | 3,724 |
Prolia® |  | 1,569 |  |  | 806 |  |  | 2,375 |  |  | 1,341 |  |  | 673 |  |  | 2,014 |
Otezla® |  | 1,284 |  |  | 335 |  |  | 1,619 |  |  | 1,280 |  |  | 298 |  |  | 1,578 |
XGEVA® |  | 1,061 |  |  | 412 |  |  | 1,473 |  |  | 1,036 |  |  | 361 |  |  | 1,397 |
Neulasta® |  | 1,215 |  |  | 168 |  |  | 1,383 |  |  | 1,538 |  |  | 219 |  |  | 1,757 |
Aranesp® |  | 409 |  |  | 709 |  |  | 1,118 |  |  | 489 |  |  | 704 |  |  | 1,193 |
Repatha® |  | 421 |  |  | 423 |  |  | 844 |  |  | 331 |  |  | 303 |  |  | 634 |
KYPROLIS® |  | 547 |  |  | 277 |  |  | 824 |  |  | 527 |  |  | 266 |  |  | 793 |
Other products |  | 3,059 |  |  | 1,974 |  |  | 5,033 |  |  | 3,164 |  |  | 1,652 |  |  | 4,816 |
Total product sales(1) |  | $ | 12,835 |  |  | $ | 5,191 |  |  | 18,026 |  |  | $ | 13,325 |  |  | $ | 4,581 |  |  | 17,906 |
Other revenues |  |  |  |  |  | 1,107 |  |  |  |  |  |  | 884 |
Total revenues |  |  |  |  |  | $ | 19,133 |  |  |  |  |  |  | $ | 18,790 |
____________ (1) Hedging gains and losses, which are included in product sales, were not material for the three and nine months ended September 30, 2021 and 2020.

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- Definition The entire disclosure of revenue from contract with customer to transfer good or service and to transfer nonfinancial asset. Includes, but is not limited to, disaggregation of revenue, credit loss recognized from contract with customer, judgment and change in judgment related to contract with customer, and asset recognized from cost incurred to obtain or fulfill contract with customer. Excludes insurance and lease contracts. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -URI http://asc.fasb.org/topic&trid=49130388 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 10 -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130551-203045 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 13 -Subparagraph (b)(2) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130556-203045 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 12 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 9 -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130550-203045 Reference 6: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 12 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045 Reference 7: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 12 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045 Reference 8: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 12 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045 Reference 9: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 15 -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130558-203045 Reference 10: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 12 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130554-203045 + Details
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