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Fair value measurement - (Fair Value of Financial Assets and Liabilities on Recurring Basis) (Details) - USD ($) $ in Millions | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
--- | --- | --- | --- | ---
Assets: |  |  |  |
Interest-bearing securities | $ 7,304 | $ 9,845 |  |
Equity securities | 831 | 477 |  |
Derivatives: |  |  |  |
Total assets | 8,400 | 10,671 |  |
Derivatives: |  |  |  |
Contingent consideration obligations | 342 | 33 | $ 61 | $ 72
Total liabilities | 876 | 603 |  |
Foreign currency contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 183 | 28 |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 39 | 237 |  |
Cross-currency swap contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 66 | 255 |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 339 | 318 |  |
Interest rate swap contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Interest rate swap contracts | 16 | 66 |  |
Derivatives: |  |  |  |
Interest rate swap contracts | 156 | 15 |  |
U.S. Treasury notes [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 47 | 130 |  |
U.S. Treasury bills [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 1,400 | 4,948 |  |
Money market mutual funds [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 5,856 | 4,765 |  |
Other short-term interest-bearing securities [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 1 | 2 |  |
Quoted prices in active markets for identical assets (Level 1) [Member] |  |  |  |
Assets: |  |  |  |
Equity securities | 611 | 477 |  |
Derivatives: |  |  |  |
Total assets | 7,914 | 10,320 |  |
Derivatives: |  |  |  |
Contingent consideration obligations | 0 | 0 |  |
Total liabilities | 0 | 0 |  |
Quoted prices in active markets for identical assets (Level 1) [Member] | Foreign currency contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 0 | 0 |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 0 | 0 |  |
Quoted prices in active markets for identical assets (Level 1) [Member] | Cross-currency swap contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 0 | 0 |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 0 | 0 |  |
Quoted prices in active markets for identical assets (Level 1) [Member] | Interest rate swap contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Interest rate swap contracts | 0 | 0 |  |
Derivatives: |  |  |  |
Interest rate swap contracts | 0 | 0 |  |
Quoted prices in active markets for identical assets (Level 1) [Member] | U.S. Treasury notes [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 47 | 130 |  |
Quoted prices in active markets for identical assets (Level 1) [Member] | U.S. Treasury bills [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 1,400 | 4,948 |  |
Quoted prices in active markets for identical assets (Level 1) [Member] | Money market mutual funds [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 5,856 | 4,765 |  |
Quoted prices in active markets for identical assets (Level 1) [Member] | Other short-term interest-bearing securities [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 0 | 0 |  |
Significant other observable inputs (Level 2) [Member] |  |  |  |
Assets: |  |  |  |
Equity securities | 0 | 0 |  |
Derivatives: |  |  |  |
Total assets | 266 | 351 |  |
Derivatives: |  |  |  |
Contingent consideration obligations | 0 | 0 |  |
Total liabilities | 534 | 570 |  |
Significant other observable inputs (Level 2) [Member] | Foreign currency contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 183 | 28 |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 39 | 237 |  |
Significant other observable inputs (Level 2) [Member] | Cross-currency swap contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 66 | 255 |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 339 | 318 |  |
Significant other observable inputs (Level 2) [Member] | Interest rate swap contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Interest rate swap contracts | 16 | 66 |  |
Derivatives: |  |  |  |
Interest rate swap contracts | 156 | 15 |  |
Significant other observable inputs (Level 2) [Member] | U.S. Treasury notes [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 0 | 0 |  |
Significant other observable inputs (Level 2) [Member] | U.S. Treasury bills [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 0 | 0 |  |
Significant other observable inputs (Level 2) [Member] | Money market mutual funds [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 0 | 0 |  |
Significant other observable inputs (Level 2) [Member] | Other short-term interest-bearing securities [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 1 | 2 |  |
Significant unobservable inputs (Level 3) [Member] |  |  |  |
Assets: |  |  |  |
Equity securities | 220 | 0 |  |
Derivatives: |  |  |  |
Total assets | 220 | 0 |  |
Derivatives: |  |  |  |
Contingent consideration obligations | 342 | 33 |  |
Total liabilities | 342 | 33 |  |
Significant unobservable inputs (Level 3) [Member] | Foreign currency contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 0 | 0 |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 0 | 0 |  |
Significant unobservable inputs (Level 3) [Member] | Cross-currency swap contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 0 | 0 |  |
Derivatives: |  |  |  |
Foreign currency and cross-currency swap contracts | 0 | 0 |  |
Significant unobservable inputs (Level 3) [Member] | Interest rate swap contracts [Member] |  |  |  |
Derivatives: |  |  |  |
Interest rate swap contracts | 0 | 0 |  |
Derivatives: |  |  |  |
Interest rate swap contracts | 0 | 0 |  |
Significant unobservable inputs (Level 3) [Member] | U.S. Treasury notes [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 0 | 0 |  |
Significant unobservable inputs (Level 3) [Member] | U.S. Treasury bills [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 0 | 0 |  |
Significant unobservable inputs (Level 3) [Member] | Money market mutual funds [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | 0 | 0 |  |
Significant unobservable inputs (Level 3) [Member] | Other short-term interest-bearing securities [Member] |  |  |  |
Assets: |  |  |  |
Interest-bearing securities | $ 0 | $ 0 |  |

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