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Acquisitions - Aggregate Consideration Paid (Details) - USD ($) $ in Millions |  |  | 12 Months Ended
--- | --- | --- | ---
Oct. 19, 2021 | Nov. 21, 2019 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Business Acquisition [Line Items] |  |  |  |  |
Additions |  |  | $ 309 | $ 0 | $ 0
Goodwill |  |  | $ 14,890 | $ 14,689 | $ 14,703
Teneobio |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Cash paid | $ 994 |  |  |  |
Additions | 309 |  |  |  |
Business asset acquisition, consideration transferred | 1,303 |  |  |  |
Cash and cash equivalents | 100 |  |  |  |
Goodwill | 251 |  |  |  |
Other assets, net | 16 |  |  |  |
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Liabilities | (253) |  |  |  |
Total assets acquired, net | 1,303 |  |  |  |
Teneobio | R & D Technology rights |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Finite-lived intangible assets | 94 |  |  |  |
Teneobio | Licensing rights |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Finite-lived intangible assets | 41 |  |  |  |
Teneobio | IPR&D |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
IPR&D | $ 1,054 |  |  |  |
Otezla |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Cash paid |  | $ 13,400 |  |  |
Transaction costs |  | 40 |  |  |
Business asset acquisition, consideration transferred |  | 13,440 |  |  |
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Liabilities |  | (24) |  |  |
Deferred credit |  | (96) |  |  |
Other liabilities, net |  | (9) |  |  |
Inventory |  | 367 |  |  |
Total assets acquired, net |  | 13,440 |  |  |
Otezla | Developed Technology Rights |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Finite-lived intangible assets |  | 13,007 |  |  |
Otezla | Marketing-Related Rights |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Finite-lived intangible assets |  | $ 195 |  |  |

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