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Revenues - Narrative (Details) $ in Millions | 12 Months Ended
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Dec. 31, 2021 USD ($) segment customer | Dec. 31, 2020 USD ($) customer | Dec. 31, 2019 USD ($) customer
Revenue from Contract with Customer [Abstract] |  |  |
Number of operating segments | segment | 1 |  |
Revenue from External Customer [Line Items] |  |  |
Number of major customers (as defined) accounting for more than 10% of total revenue | customer | 3 | 3 | 3
Major customers (as defined) accounting for more than 10% of gross trade receivables | customer | 3 | 3 |
Combined trade receivables for all major customers (as defined) as a percentage of net trade receivables | 73.00% | 74.00% |
Percentage of worldwide gross revenues derived from major customers (as defined) on a combined basis | 82.00% |  |
Total product sales | $ 25,979 | $ 25,424 | $ 23,362
Percentage of net trade receivables due from customers located outside the United States, primarily in Europe | 27.00% | 28.00% |
US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | $ 18,194 | $ 18,496 | 17,224
ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 7,785 | 6,928 | 6,138
Product sales |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 24,297 | 24,240 | 22,204
Product sales | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 17,286 | 17,985 | 16,531
Product sales | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 7,011 | 6,255 | 5,673
Enbrel® (etanercept) [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 4,465 | 4,996 | 5,226
Enbrel® (etanercept) [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 4,352 | 4,855 | 5,050
Enbrel® (etanercept) [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 113 | 141 | 176
Prolia® (denosumab) [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 3,248 | 2,763 | 2,672
Prolia® (denosumab) [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 2,150 | 1,830 | 1,772
Prolia® (denosumab) [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,098 | 933 | 900
Otezla [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 2,249 | 2,195 | 178
Otezla [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,804 | 1,790 | 139
Otezla [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 445 | 405 | 39
XGEVA® (denosumab) [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 2,018 | 1,899 | 1,935
XGEVA® (denosumab) [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,434 | 1,405 | 1,457
XGEVA® (denosumab) [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 584 | 494 | 478
Neulasta® (pegfilgrastim) [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,734 | 2,293 | 3,221
Neulasta® (pegfilgrastim) [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,514 | 2,001 | 2,814
Neulasta® (pegfilgrastim) [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 220 | 292 | 407
Aranesp® (darbepoetin alfa) [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,480 | 1,568 | 1,729
Aranesp® (darbepoetin alfa) [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 537 | 629 | 758
Aranesp® (darbepoetin alfa) [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 943 | 939 | 971
Repatha (evolocumab) [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,117 | 887 | 661
Repatha (evolocumab) [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 557 | 459 | 376
Repatha (evolocumab) [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 560 | 428 | 285
Kyprolis [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,108 | 1,065 | 1,044
Kyprolis [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 736 | 710 | 654
Kyprolis [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 372 | 355 | 390
Nplate |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,027 | 850 | 795
Nplate | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 566 | 485 | 480
Nplate | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 461 | 365 | 315
Other products [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 5,851 | 5,724 | 4,743
Other products [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 3,636 | 3,821 | 3,031
Other products [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 2,215 | 1,903 | 1,712
Other revenues [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 1,682 | 1,184 | 1,158
Other revenues [Member] | US [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 908 | 511 | 693
Other revenues [Member] | ROW [Member] |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 774 | 673 | 465
AmerisourceBergen Corporation [Member] | Product sales |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 14,783 | 14,743 | 12,301
McKesson Corporation [Member] | Product sales |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | 15,187 | 13,779 | 11,795
Cardinal Health, Inc. [Member] | Product sales |  |  |
Revenue from External Customer [Line Items] |  |  |
Total product sales | $ 7,681 | $ 7,332 | $ 6,538

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- Definition Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 18 -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8672-108599 + Details
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- Definition Amount, including tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value-added and excise. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 41 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e9038-108599 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130545-203045 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 32 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8933-108599 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 32 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8933-108599 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8906-108599 Reference 6: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599 Reference 7: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8736-108599 Reference 8: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 4 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130543-203045 Reference 9: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 42 -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e9054-108599 Reference 10: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 40 -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e9031-108599 Reference 11: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 924 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 11.L) -URI http://asc.fasb.org/extlink&oid=6472922&loc=d3e499488-122856 + Details
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