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Investments - BeiGene (Details) - USD ($) $ in Millions |  | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Sep. 30, 2021 | Dec. 31, 2021 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Jan. 02, 2020
Net Investment Income [Line Items] |  |  |  |  |  |
Payments to Acquire Equity Method Investments |  |  | $ 157 | $ 3,219 | $ 24 |
BeiGene |  |  |  |  |  |
Net Investment Income [Line Items] |  |  |  |  |  |
Ownership percentage |  | 18.40% | 18.40% | 20.50% |  | 20.50%
Equity Method Investment, Aggregate Cost |  |  |  |  |  | $ 2,800
Equity Method Investment, Quoted Market Value |  | $ 5,100 | $ 5,100 | $ 4,900 |  | 2,600
Equity Method Investment, Difference Between Carrying Amount and Underlying Equity |  |  |  |  |  | 2,400
Payments to Acquire Equity Method Investments |  |  | 50 | 569 |  |
Equity Method Investment, Change In Carrying Value, Other |  |  | 265 | 34 |  |
Company's share of profits (losses) of related party |  |  | 265 | 229 |  |
Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity |  |  | 172 | 109 |  |
Approximate carrying value of the company's equity method investment |  | 2,800 | 2,800 | 2,900 |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |  |
Equity Method Investment, Quoted Market Value |  | $ 5,100 | $ 5,100 | $ 4,900 |  | $ 2,600
BeiGene | Minimum [Member] |  |  |  |  |  |
Net Investment Income [Line Items] |  |  |  |  |  |
Finite-Lived Intangible Asset, Useful Life |  |  | 8 years |  |  |
BeiGene | Maximum [Member] |  |  |  |  |  |
Net Investment Income [Line Items] |  |  |  |  |  |
Finite-Lived Intangible Asset, Useful Life |  |  | 15 years |  |  |
Neumora Therapeutics, Inc. |  |  |  |  |  |
Net Investment Income [Line Items] |  |  |  |  |  |
Ownership percentage | 25.90% | 25.90% | 25.90% |  |  |
Equity Method Investment, Aggregate Cost | $ 257 |  |  |  |  |
Equity method investment, change in carrying value |  | $ 37 |  |  |  |
Payments to Acquire Equity Method Investments | $ 100 |  |  |  |  |

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