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Property, plant and equipment | 12 Months Ended
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Dec. 31, 2021
Property, Plant and Equipment [Abstract] |
Property, plant and equipment | Property, plant and equipment Property, plant and equipment consisted of the following (dollar amounts in millions):
|  |  | December 31,
| Useful life (in years) |  | 2021 |  | 2020
Land | — |  | $ | 279 |  |  | $ | 259 |
Buildings and improvements | 10-40 |  | 4,028 |  |  | 3,857 |
Manufacturing equipment | 8-12 |  | 3,080 |  |  | 2,865 |
Laboratory equipment | 8-12 |  | 1,193 |  |  | 1,257 |
Fixed equipment | 12 |  | 2,402 |  |  | 2,406 |
Capitalized software | 3-5 |  | 1,151 |  |  | 1,216 |
Other | 5-10 |  | 862 |  |  | 1,091 |
Construction in progress | — |  | 987 |  |  | 915 |
Property, plant and equipment, gross |  |  | 13,982 |  |  | 13,866 |
Less accumulated depreciation and amortization |  |  | (8,798) |  |  | (8,977) |
Property, plant and equipment, net |  |  | $ | 5,184 |  |  | $ | 4,889 |
During the years ended December 31, 2021, 2020 and 2019, we recognized depreciation and amortization expense associated with our property, plant and equipment of $644 million, $640 million and $635 million, respectively. Geographic information Certain geographic information with respect to property, plant and equipment, net (long-lived assets), was as follows (in millions):
| December 31,
| 2021 |  | 2020
United States | $ | 2,801 |  |  | $ | 2,473 |
Puerto Rico | 1,311 |  |  | 1,331 |
ROW | 1,072 |  |  | 1,085 |
Total property, plant and equipment, net | $ | 5,184 |  |  | $ | 4,889 |

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 6 -URI http://asc.fasb.org/extlink&oid=120429125&loc=d3e99893-112916 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -URI http://asc.fasb.org/topic&trid=2155823 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 7 -URI http://asc.fasb.org/extlink&oid=120429125&loc=SL120174063-112916 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 1 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=120429125&loc=d3e99779-112916 + Details
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