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Acquisitions - Narrative (Details) - USD ($) $ in Millions |  | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Apr. 16, 2021 | Sep. 30, 2022 | Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Dec. 31, 2021
Business Acquisition [Line Items] |  |  |  |  |  |  |
Net increase in goodwill |  |  |  |  | $ 7 |  |
Goodwill |  |  | $ 14,865 |  | 14,865 |  | $ 14,890
Loss on divestiture |  |  |  |  | 560 | $ 0 |
Payments to Acquire Businesses, Net of Cash Acquired |  |  |  |  | 0 | 1,626 |
Acquired in-process research and development |  |  | 0 | $ 1,505 | 0 | $ 1,505 |
Gensenta Ilac Sanayi vs Ticaret |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Disposal Group, Including Discontinued Operation, Assets |  |  | 80 |  | 80 |  |
Disposal Group, Including Discontinued Operation, Accrued Liabilities |  |  | 20 |  | 20 |  |
Disposal Group, Including Discontinued Operation, Assets, Current |  |  | 100 |  | 100 |  |
Gensenta Ilac Sanayi vs Ticaret | Other Operating Income (Expense) |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Loss on divestiture |  |  | 560 |  |  |  |
Gensenta Ilac Sanayi vs Ticaret | Forecast [Member] |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Proceeds from Divestiture of Businesses and Interests in Affiliates |  | $ 135 |  |  |  |  |
Teneobio |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Net increase in goodwill |  |  |  |  | 22 |  |
Cash paid |  |  |  |  | 993 |  |
Maximum additional consideration due contingent on certain milestones |  |  | 1,600 |  | 1,600 |  |
Contingent consideration obligation for acquisition |  |  |  |  | 299 |  |
Acquired in-process research and development |  |  | 991 |  | 991 |  |
Deferred tax liability |  |  | 244 |  | 244 |  |
Goodwill |  |  | 273 |  | 273 |  |
Teneobio | R & D Technology rights |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Value of intangible assets acquired |  |  |  |  | $ 115 |  |
Weighted average period of amortization |  |  |  |  | 10 years |  |
Teneobio | Licensing rights |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Value of intangible assets acquired |  |  |  |  | $ 41 |  |
Teneobio | In-process Research and Development | AMG 340 |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Acquired in-process research and development |  |  | $ 784 |  | $ 784 |  |
Five Prime Therapeutics, Inc. |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Payments to Acquire Businesses, Net of Cash Acquired | $ 1,600 |  |  |  |  |  |
Acquired in-process research and development | 1,500 |  |  |  |  |  |
Business Combination Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Assets | 177 |  |  |  |  |  |
Other liabilities | $ 47 |  |  |  |  |  |

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