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Revenues (Details) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($) segment	Jun. 30, 2021 USD ($)
Revenue from Contract with Customer [Abstract]
Number of operating segments | segment			1
Revenue from External Customer [Line Items]
Total revenues	$ 6,594	$ 6,526	$ 12,832	$ 12,427
Product sales [Member]
Revenue from External Customer [Line Items]
Total revenues	6,281	6,114	12,012	11,706
Product sales [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	4,446	4,374	8,483	8,277
Product sales [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	1,835	1,740	3,529	3,429
Enbrel® (etanercept) [Member]
Revenue from External Customer [Line Items]
Total revenues	1,051	1,144	1,913	2,068
Enbrel® (etanercept) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	1,036	1,113	1,879	2,007
Enbrel® (etanercept) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	15	31	34	61
Prolia® (denosumab) [Member]
Revenue from External Customer [Line Items]
Total revenues	922	814	1,774	1,572
Prolia® (denosumab) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	611	538	1,193	1,039
Prolia® (denosumab) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	311	276	581	533
Otezla (apremilast) [Member]
Revenue from External Customer [Line Items]
Total revenues	594	534	1,045	1,010
Otezla (apremilast) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	487	423	837	789
Otezla (apremilast) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	107	111	208	221
XGEVA® (denosumab) [Member]
Revenue from External Customer [Line Items]
Total revenues	533	488	1,035	956
XGEVA® (denosumab) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	391	355	759	689
XGEVA® (denosumab) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	142	133	276	267
Aranesp® (darbepoetin alfa) [Member]
Revenue from External Customer [Line Items]
Total revenues	357	367	715	722
Aranesp® (darbepoetin alfa) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	132	135	269	260
Aranesp® (darbepoetin alfa) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	225	232	446	462
Neulasta® (pegfilgrastim) [Member]
Revenue from External Customer [Line Items]
Total revenues	310	486	658	968
Neulasta® (pegfilgrastim) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	263	434	567	855
Neulasta® (pegfilgrastim) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	47	52	91	113
Repatha (evolocumab) [Member]
Revenue from External Customer [Line Items]
Total revenues	325	286	654	572
Repatha (evolocumab) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	154	143	319	282
Repatha (evolocumab) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	171	143	335	290
KYPROLIS® (carfilzomib) [Member]
Revenue from External Customer [Line Items]
Total revenues	317	280	604	531
KYPROLIS® (carfilzomib) [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	213	190	409	349
KYPROLIS® (carfilzomib) [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	104	90	195	182
Nplate [Member]
Revenue from External Customer [Line Items]
Total revenues	284	245	550	472
Nplate [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	156	136	312	248
Nplate [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	128	109	238	224
Other products [Member]
Revenue from External Customer [Line Items]
Total revenues	1,588	1,470	3,064	2,835
Other products [Member] | US [Member]
Revenue from External Customer [Line Items]
Total revenues	1,003	907	1,939	1,759
Other products [Member] | ROW [Member]
Revenue from External Customer [Line Items]
Total revenues	585	563	1,125	1,076
Other revenues [Member]
Revenue from External Customer [Line Items]
Total revenues	$ 313	$ 412	$ 820	$ 721

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Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues.

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