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Derivative instruments (Summary of Income and Expense Line Items) (Details) - USD ($)
$ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Derivative Instruments, Gain (Loss) [Line Items]        
Total revenues $ 6,594 $ 6,526 $ 12,832 $ 12,427
Other (expense) income, net (317) 11 (847) 24
Interest expense, net (328) (281) (623) (566)
Interest rate swap agreements [Member]        
Derivative Instruments, Gain (Loss) [Line Items]        
Gains (losses) on fair value hedging relationships, Hedged items 157 (34) 494 141
Gains (losses) on fair value hedging relationships, Derivatives designated as hedging instruments (135) 55 (450) (97)
Reclassification out of Accumulated Other Comprehensive Income [Member] | Cash flow hedges [Member] | Cross-currency swap contracts [Member]        
Derivative Instruments, Gain (Loss) [Line Items]        
Other (expense) income, net (185) 46 (263) (86)
Product sales [Member]        
Derivative Instruments, Gain (Loss) [Line Items]        
Total revenues 6,281 6,114 12,012 11,706
Product sales [Member] | Reclassification out of Accumulated Other Comprehensive Income [Member] | Cash flow hedges [Member] | Foreign currency contracts [Member]        
Derivative Instruments, Gain (Loss) [Line Items]        
Total revenues $ 53 $ (18) $ 80 $ (19)