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v3.22.2.2

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Millions | 9 Months Ended
--- | ---
Sep. 30, 2022 | Sep. 30, 2021
Cash flows from operating activities: |  |
Net income | $ 4,936 | $ 3,994
Depreciation, amortization and other | 2,506 | 2,546
Deferred income taxes | (847) | (264)
Acquired in-process research and development | 0 | 1,505
Income (Loss) from Equity Method Investments | (713) | (130)
Loss on divestiture | 565 | 0
Other items, net | 236 | 57
Changes in operating assets and liabilities, net of acquisitions: |  |
Trade receivables, net | (566) | (269)
Inventories | (651) | (215)
Other assets | 166 | (373)
Accounts payable | (142) | (260)
Accrued income taxes, net | (492) | (719)
Long-term tax liabilities | 185 | 102
Other liabilities | 463 | 219
Net cash provided by operating activities | 7,072 | 6,453
Cash flows from investing activities: |  |
Purchases of marketable securities | (2,363) | (8,901)
Proceeds from sales of marketable securities | 0 | 4,403
Proceeds from maturities of marketable securities | 447 | 7,927
Purchases of property, plant and equipment | (596) | (593)
Cash paid for acquisitions, net of cash acquired | 0 | (1,639)
Other | (59) | (234)
Net cash (used in) provided by investing activities | (2,571) | 963
Cash flows from financing activities: |  |
Net proceeds from issuance of debt | 6,938 | 4,946
Extinguishment of debt | (297) | 0
Repurchases of common stock (Note 10) | (6,360) | (3,532)
Dividends paid | (3,156) | (3,023)
Other | (113) | (104)
Net cash used in financing activities | (2,988) | (1,713)
Increase in cash and cash equivalents | 1,513 | 5,703
Cash and cash equivalents at beginning of period | 7,989 | 6,266
Cash and cash equivalents at end of period | $ 9,502 | $ 11,969

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