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v3.22.2.2

Revenues (Details) $ in Millions | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2022 USD ($) | Sep. 30, 2021 USD ($) | Sep. 30, 2022 USD ($) segment | Sep. 30, 2021 USD ($)
Revenue from Contract with Customer [Abstract] |  |  |  |
Number of operating segments | segment |  |  | 1 |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | $ 6,652 | $ 6,706 | $ 19,484 | $ 19,133
Product sales |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 6,237 | 6,320 | 18,249 | 18,026
Product sales | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 4,466 | 4,558 | 12,949 | 12,835
Product sales | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,771 | 1,762 | 5,300 | 5,191
ENBREL |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,106 | 1,289 | 3,019 | 3,357
ENBREL | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,086 | 1,263 | 2,965 | 3,270
ENBREL | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 20 | 26 | 54 | 87
Prolia |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 862 | 803 | 2,636 | 2,375
Prolia | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 590 | 530 | 1,783 | 1,569
Prolia | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 272 | 273 | 853 | 806
Otezla |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 627 | 609 | 1,672 | 1,619
Otezla | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 529 | 495 | 1,366 | 1,284
Otezla | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 98 | 114 | 306 | 335
XGEVA |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 495 | 517 | 1,530 | 1,473
XGEVA | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 363 | 372 | 1,122 | 1,061
XGEVA | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 132 | 145 | 408 | 412
Aranesp |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 358 | 396 | 1,073 | 1,118
Aranesp | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 128 | 149 | 397 | 409
Aranesp | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 230 | 247 | 676 | 709
Repatha |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 309 | 272 | 963 | 844
Repatha | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 142 | 139 | 461 | 421
Repatha | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 167 | 133 | 502 | 423
KYPROLIS |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 318 | 293 | 922 | 824
KYPROLIS | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 217 | 198 | 626 | 547
KYPROLIS | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 101 | 95 | 296 | 277
Neulasta |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 247 | 415 | 905 | 1,383
Neulasta | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 205 | 360 | 772 | 1,215
Neulasta | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 42 | 55 | 133 | 168
Nplate |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 288 | 273 | 838 | 745
Nplate | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 162 | 156 | 474 | 404
Nplate | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 126 | 117 | 364 | 341
Other products |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,627 | 1,453 | 4,691 | 4,288
Other products | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,044 | 896 | 2,983 | 2,655
Other products | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 583 | 557 | 1,708 | 1,633
Other revenues |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | $ 415 | $ 386 | $ 1,235 | $ 1,107

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