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Acquisitions and divestitures - Horizon Therapeutics PLC (Details) |  |  | 1 Months Ended |
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Dec. 31, 2022 USD ($) | Dec. 22, 2022 USD ($) traunche | Dec. 31, 2022 USD ($) | Dec. 12, 2022 USD ($) product program $ / shares
bridge credit agreement |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Bridge credit agreement amount | $ 0 |  | $ 0 |
Horizon Therapeutics [Member] |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Acquisition price per share (in dollars per share) | $ / shares |  |  |  | $ 116.50
Cash purchase price |  |  | 27,800,000,000 |
Approved products | product |  |  |  | 12
Development programs | program |  |  |  | 20
Bridge credit agreement, maximum length | 364 days |  |  |
Bridge credit agreement, initial amount | $ 28,500,000,000 |  | 28,500,000,000 | $ 28,500,000,000
Term loan credit agreement, total amount |  | $ 4,000,000,000 |  |
Term loan credit agreement, number of traunches | traunche |  | 2 |  |
Bridge credit reduced amount |  | $ 24,500,000,000 |  |
Financing costs |  | $ 97,000,000 |  |
Compensating balance, amount |  |  |  | $ 2,960,000,000
Horizon Therapeutics [Member] | bridge credit agreement |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Bridge credit agreement amount | $ 0 |  | $ 0 |

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