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Acquisitions and divestitures - ChemoCentryx Inc. Narrative (Details) - USD ($) $ / shares in Units, $ in Millions |  | 3 Months Ended |  |
--- | --- | --- | --- | ---
Oct. 20, 2022 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Business Acquisition [Line Items] |  |  |  |
Goodwill |  | $ 15,529 | $ 14,890 | $ 14,689
ChemoCentryx, Inc. |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Acquisition price per share (in dollars per share) | $ 52.00 |  |  |
Total consideration | $ 3,900 |  |  |
Acquisition related costs |  | $ 106 |  |
Cash purchase price | 3,700 |  |  |
Business acquisition, cash consideration paid to equity holders for pre-acquisition services | 181 |  |  |
Inventories | $ 41 |  |  |
Business combination, turnover period of inventory acquired | 13 months |  |  |
Deferred tax liabilities | $ 516 |  |  |
Goodwill | 667 |  |  |
ChemoCentryx, Inc. | Developed Technology Rights |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Finite-lived intangible assets – developed-product-technology rights | $ 3,497 |  |  |
Weighted average period of amortization | 11 years |  |  |

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