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Acquisitions and divestitures - Divestiture of Gensenta (Details) - USD ($) $ in Millions |  | 12 Months Ended
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Nov. 02, 2022 | Dec. 31, 2022
Business Acquisition [Line Items] |  |
Foreign currency translation, loss on divestiture of a business |  | $ 615
Proceeds from divestiture of businesses | $ 130 |
Divested assets | $ 86 |
Other general expense |  |
Business Acquisition [Line Items] |  |
Gain (Loss) on Disposition of Business |  | $ (567)

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- Definition Amount classified as assets attributable to disposal group held for sale or disposed of. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 205 -SubTopic 20 -Section 45 -Paragraph 10 -URI https://asc.fasb.org/extlink&oid=109222160&loc=d3e1107-107759 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 3 -Subparagraph (e) -URI https://asc.fasb.org/extlink&oid=109226691&loc=d3e2941-110230 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 205 -SubTopic 20 -Section 50 -Paragraph 5B -Subparagraph (e) -URI https://asc.fasb.org/extlink&oid=109222650&loc=SL51721673-107760 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 205 -SubTopic 20 -Section 45 -Paragraph 11 -URI https://asc.fasb.org/extlink&oid=109222160&loc=SL51721533-107759 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 205 -SubTopic 20 -Section 50 -Paragraph 7 -URI https://asc.fasb.org/extlink&oid=109222650&loc=SL51721683-107760 Reference 6: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 205 -SubTopic 20 -Section 50 -Paragraph 5C -Subparagraph (a)(2) -URI https://asc.fasb.org/extlink&oid=109222650&loc=SL51721675-107760 + Details
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