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Acquisitions and divestitures - Teneobio Inc. (Details) $ in Millions |  | 12 Months Ended
--- | --- | ---
Dec. 31, 2022 USD ($) | Dec. 31, 2022 USD ($) program | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($)
Business Acquisition [Line Items] |  |  |  |
Additions |  | $ 0 | $ 309 | $ 0
Goodwill | $ 15,529 | 15,529 | $ 14,890 | $ 14,689
Teneobio |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Goodwill, Purchase Accounting Adjustments |  | 22 |  |
Cash purchase price | 993 |  |  |
Maximum additional consideration due contingent on certain milestones | 1,600 | 1,600 |  |
Additions | 299 |  |  |
Deferred tax liabilities | 244 | 244 |  |
Goodwill | 273 | 273 |  |
Teneobio | R & D Technology rights |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Finite-lived Intangible Assets Acquired | $ 115 |  |  |
Weighted average period of amortization | 10 years |  |  |
Teneobio | Licensing rights |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Finite-lived Intangible Assets Acquired | $ 41 |  |  |
Teneobio | IPR&D |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Acquired in-process research and development | 991 | $ 991 |  |
Number of oncology programs comprising remaining IPR&D | program |  | 4 |  |
Teneobio | IPR&D | AMG 340 |  |  |  |
Business Acquisition [Line Items] |  |  |  |
Acquired in-process research and development | $ 784 | $ 784 |  |

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