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Income taxes (Tables)

12 Months Ended

Dec. 31, 2022

Income Tax Disclosure [Abstract]

Schedule of income before income tax, domestic and foreign

Income before income taxes included the following (in millions):

			Years ended December 31,
			2022						2021						2020
Domestic			$	3,026					$	1,850					$	4,087
Foreign			4,320						4,851						4,046
Total income before income taxes			$	7,346					$	6,701					$	8,133

Provision for income taxes

The provision for income taxes included the following (in millions):

			Years ended December 31,
			2022						2021						2020
Current provision:
Federal			$	1,721					$	865					$	921
State			44						18						34
Foreign			304						359						277
Total current provision			2,069						1,242						1,232
Deferred benefit:
Federal			(1,185)						(308)						(321)
State			(27)						(9)						9
Foreign			(63)						(117)						(51)
Total deferred benefit			(1,275)						(434)						(363)
Total provision for income taxes			$	794					$	808					$	869

Significant components of deferred tax assets and liabilities

Significant components of our deferred tax assets and liabilities were as follows (in millions):

			December 31,
			2022						2021
Deferred income tax assets:
NOL and credit carryforwards			$	1,344					$	1,065
Accrued expenses			584						600
Capitalized research and development expenses			515						—
Investments			270						—
Expenses capitalized for tax			211						244
Earnings of foreign subsidiaries			192						—
Stock-based compensation			104						96
Other			317						326
Total deferred income tax assets			3,537						2,331
Valuation allowance			(718)						(663)
Net deferred income tax assets			2,819						1,668
Deferred income tax liabilities:
Acquired intangible assets			(1,238)						(824)
Debt			(272)						(275)
Fixed assets			(112)						(129)
Other			(254)						(221)
Total deferred income tax liabilities			(1,876)						(1,449)
Total deferred income taxes, net			$	943					$	219

Reconciliation of total gross amounts of unrecognized tax benefits (excluding interest, penalties, foreign tax credits and the federal tax benefit of state taxes related to unrecognized tax benefits)

The reconciliations of the total gross amounts of UTBs were as follows (in millions):

			Years ended December 31,
			2022						2021						2020
Beginning balance			$	3,546					$	3,352					$	3,287
Additions based on tax positions related to the current year			151						171						165
Additions based on tax positions related to prior years			90						35						3
Reductions for tax positions of prior years			(14)						(4)						(35)
Reductions for expiration of statute of limitations			(3)						—						—
Settlements			—						(8)						(68)
Ending balance			$	3,770					$	3,546					$	3,352

Reconciliation between the federal statutory tax rate and effective tax rate

The reconciliations between the federal statutory tax rate applied to income before income taxes and our effective tax rate were as follows:

			Years ended December 31,
			2022						2021						2020
Federal statutory tax rate			21.0		%				21.0		%				21.0		%
Foreign earnings			(5.6)		%				(7.8)		%				(4.7)		%
Foreign-derived intangible income			(1.3)		%				(1.0)		%				(0.7)		%
Credits, Puerto Rico excise tax			(2.8)		%				(3.4)		%				(2.9)		%
Interest on uncertain tax positions			1.9		%				1.1		%				1.1		%
Credits, primarily federal R&D			(2.0)		%				(2.1)		%				(1.4)		%
Acquisition IPR&D			—		%				4.9		%				—		%
Audit settlements			—		%				—		%				(1.0)		%
Other, net			(0.4)		%				(0.6)		%				(0.7)		%
Effective tax rate			10.8		%				12.1		%				10.7		%

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Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years.

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Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

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Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

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Tabular disclosure of income before income tax between domestic and foreign jurisdictions.

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Tabular disclosure for tax positions taken in the tax returns filed or to be filed for which it is more likely than not that the tax position will not be sustained upon examination by taxing authorities and other income tax contingencies. Includes, but is not limited to, interest and penalties, reconciliation of unrecognized tax benefits, unrecognized tax benefits that would affect the effective tax rate, tax years that remain subject to examination by tax jurisdictions, and information about positions for which it is reasonably possible that amounts unrecognized will significantly change within 12 months.

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