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Goodwill and other intangible assets - (Tables)
 12 Months Ended
Dec. 31, 2022
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of goodwill
The changes in the carrying amounts of goodwill were as follows (in millions):
December 31,
20222021
Beginning balance$14,890 $14,689 
Changes to goodwill resulting from acquisitions and divestitures, net(1)
651 251 
Currency translation adjustments(12)(50)
Ending balance$15,529 $14,890 
____________
(1)    For 2022, the changes to goodwill consist of goodwill resulting from the acquisition of ChemoCentryx, changes to the acquisition date fair values of net assets acquired in the acquisition of Teneobio and the nonstrategic Gensenta divestiture. See Note 2, Acquisitions and divestitures.
Schedule of identifiable intangible assets
Other intangible assets consisted of the following (in millions):
December 31,
 20222021
 Gross
carrying
amounts		Accumulated
amortization		Other intangible
assets, net		Gross
carrying
amounts		Accumulated
amortization		Other intangible
assets, net
Finite-lived intangible assets:
Developed-product-technology rights$29,028 $(15,045)$13,983 $25,561 $(12,769)$12,792 
Licensing rights3,864 (3,123)741 3,807 (2,973)834 
Marketing-related rights1,326 (1,167)159 1,354 (1,112)242 
R&D technology rights1,378 (1,190)188 1,377 (1,133)244 
Total finite-lived intangible assets35,596 (20,525)15,071 32,099 (17,987)14,112 
Indefinite-lived intangible assets:
IPR&D1,009 — 1,009 1,070 — 1,070 
Total other intangible assets$36,605 $(20,525)$16,080 $33,169 $(17,987)$15,182