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Acquisitions and divestitures - Divestiture of Gensenta (Details) - USD ($) $ in Millions		12 Months Ended
	Nov. 02, 2022	Dec. 31, 2022
Business Acquisition [Line Items]
Foreign currency translation, loss on divestiture of a business		$ 615
Proceeds from divestiture of businesses	$ 130
Divested assets	$ 86
Other general expense
Business Acquisition [Line Items]
Gain (Loss) on Disposition of Business		$ (567)

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Amount classified as assets attributable to disposal group held for sale or disposed of.

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