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Collaborations - BeiGene (Details) - USD ($)		12 Months Ended
	Jan. 02, 2020	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue from Contract with Customer, Including Assessed Tax		$ 26,323,000,000	$ 25,979,000,000	$ 25,424,000,000
BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and Development Arrangement, Contract to Perform for Others, Costs Incurred, Gross	$ 1,250,000,000
BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Equity Method Investment, Aggregate Cost	$ 2,800,000,000
Other current assets [Member] | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Related Party Transaction, Due from (to) Related Party		47,000,000	61,000,000
Trade Accounts Receivable | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Related Party Transaction, Due from (to) Related Party		6,000,000	21,000,000
Research and Development Expense [Member] | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cost recoveries		199,000,000	220,000,000	$ 225,000,000
Selling, general and administrative [Member] | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Profit and loss share of expenses		53,000,000	64,000,000
BeiGene | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue from Contract with Customer, Including Assessed Tax		$ 64,000,000	$ 72,000,000

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