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Investments - BeiGene (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Jan. 02, 2020
Net Investment Income [Line Items]        
Payments to Acquire Equity Method Investments $ 18 $ 157 $ 3,219  
Company's share of profits (losses) of related party $ (891) $ (33) (65)  
BeiGene        
Net Investment Income [Line Items]        
Ownership percentage 18.20% 18.40%   20.50%
BeiGene        
Net Investment Income [Line Items]        
Equity Method Investment, Aggregate Cost       $ 2,800
Equity Method Investment, Quoted Market Value $ 4,200 $ 5,100   2,600
Equity Method Investment, Difference Between Carrying Amount and Underlying Equity       $ 2,400
Payments to Acquire Equity Method Investments   50 569  
Equity Method Investment, Change In Carrying Value, Other 11 265 34  
Company's share of profits (losses) of related party (394) (265) (229)  
Equity Method Investment, Amortization of Difference Between Carrying Amount and Underlying Equity 190 172 $ 109  
Approximate carrying value of the company's equity method investment $ 2,200 $ 2,800    
BeiGene | Minimum        
Net Investment Income [Line Items]        
Finite-Lived Intangible Asset, Useful Life 8 years      
BeiGene | Maximum        
Net Investment Income [Line Items]        
Finite-Lived Intangible Asset, Useful Life 15 years