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Property, plant and equipment (Schedule) (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Property, Plant and Equipment [Line Items]
Land	$ 292	$ 279
Buildings and improvements	4,201	4,028
Manufacturing equipment	3,105	3,080
Laboratory equipment	1,277	1,193
Fixed equipment	2,478	2,402
Capitalized software	1,215	1,151
Other	929	862
Construction in progress	1,213	987
Property, plant and equipment, gross	14,710	13,982
Less accumulated depreciation and amortization	(9,283)	(8,798)
Property, plant and equipment, net	5,427	5,184
Depreciation and amortization charges associated with property, plant and equipment	$ 661	$ 644	$ 640
Buildings and improvements [Member] | Minimum
Property, Plant and Equipment [Line Items]
Useful life (in years)	10 years
Buildings and improvements [Member] | Maximum
Property, Plant and Equipment [Line Items]
Useful life (in years)	40 years
Manufacturing equipment [Member] | Minimum
Property, Plant and Equipment [Line Items]
Useful life (in years)	8 years
Manufacturing equipment [Member] | Maximum
Property, Plant and Equipment [Line Items]
Useful life (in years)	12 years
Laboratory equipment [Member] | Minimum
Property, Plant and Equipment [Line Items]
Useful life (in years)	8 years
Laboratory equipment [Member] | Maximum
Property, Plant and Equipment [Line Items]
Useful life (in years)	12 years
Fixed equipment [Member]
Property, Plant and Equipment [Line Items]
Useful life (in years)	12 years
Capitalized software [Member] | Minimum
Property, Plant and Equipment [Line Items]
Useful life (in years)	3 years
Capitalized software [Member] | Maximum
Property, Plant and Equipment [Line Items]
Useful life (in years)	5 years
Other [Member] | Minimum
Property, Plant and Equipment [Line Items]
Useful life (in years)	5 years
Other [Member] | Maximum
Property, Plant and Equipment [Line Items]
Useful life (in years)	10 years

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Fixed equipment

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Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation of building structures held for productive use including addition, improvement, or renovation to the structure, including, but not limited to, interior masonry, interior flooring, electrical, and plumbing.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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