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Revenues - Summary of Revenues (Details) - USD ($) $ in Millions | 3 Months Ended
--- | ---
Mar. 31, 2023 | Mar. 31, 2022
Revenue from External Customer [Line Items] |  |
Total revenues | $ 6,105 | $ 6,238
Product sales |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 5,846 | 5,731
Product sales | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 3,975 | 4,037
Product sales | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 1,871 | 1,694
Prolia |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 927 | 852
Prolia | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 623 | 582
Prolia | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 304 | 270
ENBREL |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 579 | 862
ENBREL | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 564 | 843
ENBREL | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 15 | 19
XGEVA |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 536 | 502
XGEVA | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 384 | 368
XGEVA | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 152 | 134
Otezla |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 392 | 451
Otezla | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 294 | 350
Otezla | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 98 | 101
Repatha |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 388 | 329
Repatha | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 197 | 165
Repatha | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 191 | 164
Nplate |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 362 | 266
Nplate | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 246 | 156
Nplate | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 116 | 110
KYPROLIS |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 358 | 287
KYPROLIS | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 234 | 196
KYPROLIS | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 124 | 91
Aranesp |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 355 | 358
Aranesp | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 115 | 137
Aranesp | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 240 | 221
EVENITY |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 254 | 170
EVENITY | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 164 | 110
EVENITY | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 90 | 60
Other products |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 1,695 | 1,654
Other products | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 1,154 | 1,130
Other products | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 541 | 524
Other revenues |  |
Revenue from External Customer [Line Items] |  |
Total revenues | $ 259 | $ 507

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