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Acquisitions and divestitures - Narrative: Proposed Acquisition of Horizon Therapeutics plc (Details) - Horizon Therapeutics $ / shares in Units, $ in Billions	3 Months Ended
	Mar. 31, 2023 USD ($)	Dec. 12, 2022 program product $ / shares
Business Acquisition [Line Items]
Business acquisition, share price (in dollars per share) | $ / shares		$ 116.50
Cash payment | $	$ 27.8
Approved products | product		12
Development programs | program		20

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Development programs

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Price of a single share of a number of saleable stocks paid or offered to be paid in a business combination.

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The cash outflow associated with the acquisition of business during the period. The cash portion only of the acquisition price.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 805
-SubTopic 30
-Section 50
-Paragraph 1
-Subparagraph (b)(1)
-URI https://asc.fasb.org/extlink&oid=126975305&loc=d3e6927-128479

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 13
-Subparagraph (b)
-URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3213-108585

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