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Acquisitions and divestitures - Narrative: Acquisition of ChemoCentryx Inc (Details) - USD ($) $ / shares in Units, $ in Millions |  | 6 Months Ended |
--- | --- | --- | ---
Oct. 20, 2022 | Jun. 30, 2023 | Dec. 31, 2022
Business Acquisition [Line Items] |  |  |
Cash payment |  | $ 27,800 |
Goodwill |  | 15,531 | $ 15,529
ChemoCentryx, Inc. |  |  |
Business Acquisition [Line Items] |  |  |
Business acquisition, share price (in dollars per share) | $ 52.00 |  |
Business asset acquisition, consideration transferred | $ 3,900 |  |
Goodwill increase (decrease) |  | (4) |
Cash payment | 3,700 |  |
Business acquisition, cash consideration paid to equity holders for pre-acquisition services | $ 181 |  |
Finite-lived intangible assets—developed-product-technology rights |  | 3,499 |
Inventories |  | $ 41 |
Business combination, turnover period of inventory acquired |  | 13 months |
Deferred tax liability |  | $ 516 |
Goodwill |  | 663 |
ChemoCentryx, Inc. | Developed Technology Rights |  |  |
Business Acquisition [Line Items] |  |  |
Finite-lived intangible assets—developed-product-technology rights |  | $ 3,500 |
Weighted average period of amortization |  | 11 years |

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