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Revenues - Summary of Revenues (Details) - USD ($) $ in Millions | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | $ 6,903 | $ 6,652 | $ 19,994 | $ 19,484
Product sales |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 6,548 | 6,237 | 19,077 | 18,249
Product sales | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 4,691 | 4,466 | 13,402 | 12,949
Product sales | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,857 | 1,771 | 5,675 | 5,300
Prolia |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 986 | 862 | 2,941 | 2,636
Prolia | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 673 | 590 | 1,987 | 1,783
Prolia | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 313 | 272 | 954 | 853
ENBREL |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,035 | 1,106 | 2,682 | 3,019
ENBREL | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,026 | 1,086 | 2,645 | 2,965
ENBREL | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 9 | 20 | 37 | 54
XGEVA |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 519 | 495 | 1,585 | 1,530
XGEVA | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 374 | 363 | 1,145 | 1,122
XGEVA | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 145 | 132 | 440 | 408
Otezla |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 567 | 627 | 1,559 | 1,672
Otezla | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 462 | 529 | 1,251 | 1,366
Otezla | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 105 | 98 | 308 | 306
Repatha |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 406 | 309 | 1,218 | 963
Repatha | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 183 | 142 | 592 | 461
Repatha | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 223 | 167 | 626 | 502
Nplate |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 419 | 288 | 1,091 | 838
Nplate | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 322 | 162 | 744 | 474
Nplate | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 97 | 126 | 347 | 364
KYPROLIS |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 349 | 318 | 1,053 | 922
KYPROLIS | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 231 | 217 | 699 | 626
KYPROLIS | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 118 | 101 | 354 | 296
Aranesp |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 323 | 358 | 1,043 | 1,073
Aranesp | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 107 | 128 | 345 | 397
Aranesp | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 216 | 230 | 698 | 676
EVENITY |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 307 | 201 | 842 | 562
EVENITY | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 214 | 136 | 570 | 376
EVENITY | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 93 | 65 | 272 | 186
Other products |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,637 | 1,673 | 5,063 | 5,034
Other products | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,099 | 1,113 | 3,424 | 3,379
Other products | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 538 | 560 | 1,639 | 1,655
Other revenues |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | $ 355 | $ 415 | $ 917 | $ 1,235

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