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Collaborations - Novartis AG (Details) - Novartis Pharma AG - USD ($) $ in Millions | 12 Months Ended
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Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Research and development |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Cost recoveries | $ 42 | $ 53 |
Selling, general and administrative |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Cost recoveries |  |  | $ 160
Cost of sales |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Royalties due |  |  | $ 116

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