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Acquisitions and divestitures - Divestiture of Gensenta (Details) - USD ($) $ in Millions |  | 12 Months Ended
--- | --- | ---
Nov. 02, 2022 | Dec. 31, 2022
Business Acquisition [Line Items] |  |
Proceeds from divestiture of businesses | $ 130 |
Divested assets | $ 86 |
Foreign currency translation, loss on divestiture of a business |  | $ 615
Other general expense |  |
Business Acquisition [Line Items] |  |
Loss on divestiture |  | $ 567

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