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Fair value measurement - Narrative (Details) - USD ($) $ in Millions | 3 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Dec. 31, 2023 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Oct. 19, 2021
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Net changes in valuations |  | $ 165 | $ 65 | $ (7) |
Aggregate fair value of long-term debt, including current portion | $ 59,200 | 59,200 | 35,000 |  |
Carrying value of long-term debt, including current portion | 64,613 | $ 64,613 | 38,945 |  |
Teneobio, Inc. |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Maximum additional consideration due contingent on certain milestones |  |  |  |  | $ 1,600
Teneobio, Inc. | AMG 340 development program liability |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Net changes in valuations | $ 165 |  |  |  |
Other Noncurrent Assets | BeiGene |  |  |  |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |  |  |  |
Carrying and fair value of investment |  |  | 4,200 |  |
Approximate carrying value of the company's equity method investment |  |  | $ 2,200 |  |

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