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Collaborations - BeiGene (Details) - USD ($) $ in Millions		12 Months Ended
	Jan. 02, 2020	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenues		$ 28,190	$ 26,323	$ 25,979
Due from related party		7,268	5,563
Due from related party		2,602	2,388
BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development arrangement, contract to provide cash and development services, maximum amount	$ 1,250
BeiGene | Related Party
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Due from related party		16	6
Due from related party		44	47
BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Equity method investment, aggregate cost	$ 2,800
Research and development | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cost recoveries		109	199	220
Selling, general and administrative | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Profit and loss share of expenses		40	53	64
BeiGene | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenues		$ 125	$ 64	$ 72

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