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Collaborations - Novartis AG (Details) - Novartis Pharma AG - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Research and development
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cost recoveries	$ 42	$ 53
Selling, general and administrative
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cost recoveries			$ 160
Cost of sales
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Royalties due			$ 116

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