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Revenues - Disaggregation of Revenue by Product and by Geographic Area (Details) - USD ($) $ in Millions | 3 Months Ended
--- | ---
Mar. 31, 2024 | Mar. 31, 2023
Revenue from External Customer [Line Items] |  |
Total revenues | $ 7,447 | $ 6,105
Product sales |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 7,118 | 5,846
Product sales | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 4,973 | 3,975
Product sales | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 2,145 | 1,871
Prolia |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 999 | 927
Prolia | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 657 | 623
Prolia | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 342 | 304
ENBREL |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 567 | 579
ENBREL | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 561 | 564
ENBREL | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 6 | 15
XGEVA |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 561 | 536
XGEVA | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 366 | 384
XGEVA | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 195 | 152
Repatha |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 517 | 388
Repatha | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 273 | 197
Repatha | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 244 | 191
TEPEZZA |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 424 | 0
TEPEZZA | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 419 | 0
TEPEZZA | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 5 | 0
Otezla |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 394 | 392
Otezla | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 293 | 294
Otezla | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 101 | 98
KYPROLIS |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 376 | 358
KYPROLIS | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 234 | 234
KYPROLIS | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 142 | 124
Aranesp |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 349 | 355
Aranesp | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 100 | 115
Aranesp | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 249 | 240
EVENITY |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 342 | 254
EVENITY | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 236 | 164
EVENITY | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 106 | 90
Nplate |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 317 | 362
Nplate | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 190 | 246
Nplate | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 127 | 116
Vectibix |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 247 | 233
Vectibix | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 120 | 111
Vectibix | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 127 | 122
BLINCYTO |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 244 | 194
BLINCYTO | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 153 | 126
BLINCYTO | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 91 | 68
KRYSTEXXA |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 235 | 0
KRYSTEXXA | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 235 | 0
KRYSTEXXA | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 0 | 0
TEZSPIRE |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 173 | 96
TEZSPIRE | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 173 | 96
TEZSPIRE | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 0 | 0
Other products |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 1,373 | 1,172
Other products | U.S. |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 963 | 821
Other products | ROW |  |
Revenue from External Customer [Line Items] |  |
Total revenues | 410 | 351
Other revenues |  |
Revenue from External Customer [Line Items] |  |
Total revenues | $ 329 | $ 259

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