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Revenues - Disaggregation of Revenue by Product and by Geographic Area (Details) - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2024 | Jun. 30, 2023 | Jun. 30, 2024 | Jun. 30, 2023
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | $ 8,388 | $ 6,986 | $ 15,835 | $ 13,091
Product sales |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 8,041 | 6,683 | 15,159 | 12,529
Product sales | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 5,840 | 4,736 | 10,813 | 8,711
Product sales | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 2,201 | 1,947 | 4,346 | 3,818
Prolia |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,165 | 1,028 | 2,164 | 1,955
Prolia | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 770 | 691 | 1,427 | 1,314
Prolia | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 395 | 337 | 737 | 641
ENBREL |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 909 | 1,068 | 1,476 | 1,647
ENBREL | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 902 | 1,055 | 1,463 | 1,619
ENBREL | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 7 | 13 | 13 | 28
XGEVA |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 562 | 530 | 1,123 | 1,066
XGEVA | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 399 | 387 | 765 | 771
XGEVA | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 163 | 143 | 358 | 295
Repatha |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 532 | 424 | 1,049 | 812
Repatha | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 270 | 212 | 543 | 409
Repatha | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 262 | 212 | 506 | 403
Otezla |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 544 | 600 | 938 | 992
Otezla | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 432 | 495 | 725 | 789
Otezla | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 112 | 105 | 213 | 203
TEPEZZA |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 479 | 0 | 903 | 0
TEPEZZA | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 478 | 0 | 897 | 0
TEPEZZA | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1 | 0 | 6 | 0
KYPROLIS |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 377 | 346 | 753 | 704
KYPROLIS | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 240 | 234 | 474 | 468
KYPROLIS | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 137 | 112 | 279 | 236
EVENITY |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 391 | 281 | 733 | 535
EVENITY | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 281 | 192 | 517 | 356
EVENITY | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 110 | 89 | 216 | 179
Aranesp |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 348 | 365 | 697 | 720
Aranesp | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 91 | 123 | 191 | 238
Aranesp | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 257 | 242 | 506 | 482
Nplate |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 346 | 310 | 663 | 672
Nplate | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 214 | 176 | 404 | 422
Nplate | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 132 | 134 | 259 | 250
KRYSTEXXA |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 294 | 0 | 529 | 0
KRYSTEXXA | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 294 | 0 | 529 | 0
KRYSTEXXA | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 0 | 0 | 0 | 0
Vectibix |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 270 | 248 | 517 | 481
Vectibix | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 133 | 118 | 253 | 229
Vectibix | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 137 | 130 | 264 | 252
BLINCYTO |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 264 | 206 | 508 | 400
BLINCYTO | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 165 | 145 | 318 | 271
BLINCYTO | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 99 | 61 | 190 | 129
TEZSPIRE |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 234 | 133 | 407 | 229
TEZSPIRE | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 234 | 133 | 407 | 229
TEZSPIRE | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 0 | 0 | 0 | 0
Other products |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 1,326 | 1,144 | 2,699 | 2,316
Other products | U.S. |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 937 | 775 | 1,900 | 1,596
Other products | ROW |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | 389 | 369 | 799 | 720
Other revenues |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Total revenues | $ 347 | $ 303 | $ 676 | $ 562

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