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Revenues (Tables)
6 Months Ended
Jun. 30, 2024
Revenue from Contract with Customer [Abstract]  
Disaggregation of Revenue by Product and by Geographic Area
Revenues were as follows (in millions):
Three months ended June 30,
20242023
U.S.ROWTotalU.S.ROWTotal
Prolia$770 $395 $1,165 $691 $337 $1,028 
ENBREL902 909 1,055 13 1,068 
XGEVA399 163 562 387 143 530 
Repatha270 262 532 212 212 424 
Otezla432 112 544 495 105 600 
TEPEZZA(1)
478 479 — — — 
KYPROLIS240 137 377 234 112 346 
EVENITY281 110 391 192 89 281 
Aranesp91 257 348 123 242 365 
Nplate214 132 346 176 134 310 
KRYSTEXXA(1)
294 — 294 — — — 
Vectibix133 137 270 118 130 248 
BLINCYTO165 99 264 145 61 206 
TEZSPIRE(2)
234 — 234 133 — 133 
Other products(3)
937 389 1,326 775 369 1,144 
Total product sales(4)
$5,840 $2,201 8,041 $4,736 $1,947 6,683 
Other revenues347 303 
Total revenues$8,388 $6,986 
Six months ended June 30,
20242023
U.S.ROWTotalU.S.ROWTotal
Prolia$1,427 $737 $2,164 $1,314 $641 $1,955 
ENBREL1,463131,476 1,619281,647 
XGEVA7653581,123 7712951,066 
Repatha5435061,049 409403812 
Otezla725213938 789203992 
TEPEZZA(1)
8976903 — — — 
KYPROLIS474279753 468236704 
EVENITY517216733 356179535 
Aranesp191506697 238482720 
Nplate404259663 422250672 
KRYSTEXXA(1)
529— 529 — — — 
Vectibix253264517 229252481 
BLINCYTO318190508 271129400 
TEZSPIRE(2)
407— 407 229— 229 
Other products(3)
1,900 7992,699 1,596 7202,316 
Total product sales(4)
$10,813 $4,346 15,159 $8,711 $3,818 12,529 
Other revenues676 562 
Total revenues$15,835 $13,091 
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(1)    TEPEZZA and KRYSTEXXA were acquired from the acquisition of Horizon on October 6, 2023, and include product sales in the periods after the acquisition date.
(2)    TEZSPIRE is marketed by our collaborator AstraZeneca outside the United States.
(3)    Consists of product sales of our non-principal products.
(4)    Hedging gains and losses, which are included in product sales, were not material for the three and six months ended June 30, 2024 and 2023.