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Stockholders' equity - Reclassifications Out of Accumulated Other Comprehensive Income (Details) - USD ($) $ in Millions	3 Months Ended				6 Months Ended
	Jun. 30, 2024	Mar. 31, 2024	Jun. 30, 2023	Mar. 31, 2023	Jun. 30, 2024	Jun. 30, 2023
Reclassification out of Accumulated Other Comprehensive Income [Line Items]
Product sales	$ 8,388		$ 6,986		$ 15,835	$ 13,091
Other (expense) income, net	(307)		(318)		(542)	1,746
Income before income taxes	794		1,614		726	5,056
Provision for income taxes	(48)		(235)		(93)	(836)
Net income	746	$ (113)	1,379	$ 2,841	633	4,220
Product sales
Reclassification out of Accumulated Other Comprehensive Income [Line Items]
Product sales	8,041		6,683		15,159	12,529
Reclassification out of Accumulated Other Comprehensive Income | Cash flow hedges
Reclassification out of Accumulated Other Comprehensive Income [Line Items]
Income before income taxes	52		87		72	117
Provision for income taxes	(11)		(19)		(15)	(25)
Net income	41		68		57	92
Reclassification out of Accumulated Other Comprehensive Income | Foreign currency contract gains | Cash flow hedges | Product sales
Reclassification out of Accumulated Other Comprehensive Income [Line Items]
Product sales	55		36		106	88
Reclassification out of Accumulated Other Comprehensive Income | Cross-currency swap contract (losses) gains | Cash flow hedges
Reclassification out of Accumulated Other Comprehensive Income [Line Items]
Other (expense) income, net	(3)		51		(34)	29
Reclassification out of Accumulated Other Comprehensive Income | Cash flow hedges | Foreign currency contract gains | Cash flow hedges | Product sales
Reclassification out of Accumulated Other Comprehensive Income [Line Items]
Product sales	55		36		106	88
Reclassification out of Accumulated Other Comprehensive Income | Cash flow hedges | Cross-currency swap contract (losses) gains | Cash flow hedges
Reclassification out of Accumulated Other Comprehensive Income [Line Items]
Other (expense) income, net	$ (3)		$ 51		$ (34)	$ 29

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