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Goodwill and other intangible assets (Tables) | 12 Months Ended
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Dec. 31, 2024
Goodwill and Intangible Assets Disclosure [Abstract] |
Schedule of Goodwill | The changes in the carrying amounts of goodwill were as follows (in millions):
| December 31,
| 2024 |  | 2023
Beginning balance | $ | 18,629 |  |  | $ | 15,529 |
Changes to goodwill resulting from acquisitions, net(1) | 25 |  |  | 3,089 |
Foreign currency translation adjustments | (17) |  |  | 11 |
Ending balance | $ | 18,637 |  |  | $ | 18,629 |
____________ (1) For 2024, changes to Goodwill consisted of measurement-period adjustments related to our Horizon acquisition. For 2023, changes to Goodwill primarily consisted of goodwill resulting from our Horizon acquisition. See Note 4, Acquisitions and divestitures.
Schedule of Other Intangible Assets | Other intangible assets consisted of the following (in millions):
| December 31,
| 2024 |  | 2023
| Gross carrying amounts |  | Accumulated amortization |  | Other intangible assets, net |  | Gross carrying amounts |  | Accumulated amortization |  | Other intangible assets, net
Finite-lived intangible assets: |  |  |  |  |  |  |  |  |  |  |
Developed-product-technology rights | $ | 48,611 |  |  | $ | (22,594) |  |  | $ | 26,017 |  |  | $ | 48,631 |  |  | $ | (18,049) |  |  | $ | 30,582 |
Licensing rights | 3,875 |  |  | (3,392) |  |  | 483 |  |  | 3,865 |  |  | (3,265) |  |  | 600 |
Marketing-related rights | 1,202 |  |  | (1,202) |  |  | — |  |  | 1,339 |  |  | (1,264) |  |  | 75 |
R&D technology rights | 1,374 |  |  | (1,235) |  |  | 139 |  |  | 1,394 |  |  | (1,228) |  |  | 166 |
Total finite-lived intangible assets | 55,062 |  |  | (28,423) |  |  | 26,639 |  |  | 55,229 |  |  | (23,806) |  |  | 31,423 |
Indefinite-lived intangible assets: |  |  |  |  |  |  |  |  |  |  |
In-process research and development | 1,060 |  |  | — |  |  | 1,060 |  |  | 1,218 |  |  | — |  |  | 1,218 |
Total other intangible assets | $ | 56,122 |  |  | $ | (28,423) |  |  | $ | 27,699 |  |  | $ | 56,447 |  |  | $ | (23,806) |  |  | $ | 32,641 |

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