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Collaborations - BeiGene (Details) - USD ($) $ in Millions |  | 12 Months Ended
--- | --- | ---
Jan. 02, 2020 | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Total revenues |  | $ 33,424 | $ 28,190 | $ 26,323
BeiGene |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Research and development arrangement, contract to provide cash and development services, maximum amount | $ 1,250 |  |  |
BeiGene |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Equity method investment, aggregate cost | $ 2,800 |  |  |
Research and Development Expense | BeiGene |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Cost recoveries |  | 122 | 109 | 199
BeiGene | BeiGene |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Total revenues |  | $ 259 | $ 125 | $ 64

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