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Derivative instruments (Tables) | 12 Months Ended
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Dec. 31, 2024
Derivative Instruments and Hedging Activities Disclosure [Abstract] |
Schedule of Cross-Currency Swaps | The notional amounts and interest rates of our cross-currency swaps as of December 31, 2024, were as follows (notional amounts in millions):
|  | Foreign currency |  | U.S. dollars
Hedged notes |  | Notional amounts |  | Interest rates |  | Notional amounts |  | Interest rates
2.00% 2026 euro Notes |  | € | 750 |  |  | 2.0 | % |  | $ | 833 |  |  | 3.9 | %
5.50% 2026 pound sterling Notes |  | £ | 475 |  |  | 5.5 | % |  | $ | 747 |  |  | 6.0 | %
4.00% 2029 pound sterling Notes |  | £ | 700 |  |  | 4.0 | % |  | $ | 1,111 |  |  | 4.6 | %
Schedule of Unrealized Gains and Losses Recognized in AOCI | The unrealized gains and losses recognized in AOCI for our derivative instruments designated as cash flow hedges were as follows (in millions):
|  |  |  | Years ended December 31,
Derivatives in cash flow hedging relationships |  |  |  | 2024 |  | 2023 |  | 2022
Foreign currency forward contracts |  |  |  | $ | 585 |  |  | $ | (14) |  |  | $ | 308 |
Cross-currency swap contracts |  |  |  | (79) |  |  | 73 |  |  | (219) |
Forward interest rate contracts |  |  |  | — |  |  | (31) |  |  | (5) |
Total unrealized gains |  |  |  | $ | 506 |  |  | $ | 28 |  |  | $ | 84 |
Schedule of Interest Rate Derivatives | As of December 31, 2024 and 2023, the interest rates on the portion of notes for which we have entered into interest rate swap contracts and the related notional amounts of these contracts were as follows (dollar amounts in millions):
|  | December 31,
|  | 2024 |  | 2023
Notes |  | Notional amounts |  | Interest rates |  | Notional amounts |  | Interest rates
3.625% 2024 Notes |  | $ | — |  |  | N/A |  | $ | 1,400 |  |  | SOFR + 3.4%
3.125% 2025 Notes |  | 1,000 |  |  | SOFR + 2.1% |  | 1,000 |  |  | SOFR + 2.1%
2.60% 2026 Notes |  | 1,250 |  |  | SOFR + 2.1% |  | 1,250 |  |  | SOFR + 2.1%
2.45% 2030 Notes |  | 1,000 |  |  | SOFR + 1.3% |  | 1,000 |  |  | SOFR + 1.3%
2.30% 2031 Notes |  | 500 |  |  | SOFR + 1.1% |  | 500 |  |  | SOFR + 1.1%
5.25% 2033 Notes |  | 1,400 |  |  | SOFR + 1.8% |  | — |  |  | N/A
4.663% 2051 Notes |  | 1,500 |  |  | SOFR + 4.3% |  | 1,500 |  |  | SOFR + 4.3%
Total notional amounts |  | $ | 6,650 |  |  |  |  | $ | 6,650 |  |  |
N/A = not applicable
Schedule of Hedged Liabilities and Cumulative Amount | The hedged liabilities and related cumulative-basis adjustments for fair value hedges of those liabilities were recorded in the Consolidated Balance Sheets as follows (in millions):
|  | Carrying amounts of hedged liabilities(1) |  | Cumulative amounts of fair value hedging adjustments related to the carrying amounts of the hedged liabilities(2)
|  | December 31, |  | December 31,
Consolidated Balance Sheets locations |  | 2024 |  | 2023 |  | 2024 |  | 2023
Current portion of long-term debt |  | $ | 1,045 |  |  | $ | 1,441 |  |  | $ | 45 |  |  | $ | 41 |
Long-term debt |  | $ | 5,152 |  |  | $ | 4,788 |  |  | $ | (388) |  |  | $ | (355) |
____________ (1)Current portion of long-term debt includes $56 million and $69 million of carrying value with discontinued hedging relationships as of December 31, 2024 and 2023, respectively. Long-term debt includes $232 million and $288 million of carrying value with discontinued hedging relationships as of December 31, 2024 and 2023, respectively. (2)Current portion of long-term debt includes $56 million and $69 million of hedging adjustments on discontinued hedging relationships as of December 31, 2024 and 2023, respectively. Long-term debt includes $132 million and $188 million of hedging adjustments on discontinued hedging relationships as of December 31, 2024 and 2023, respectively.
Schedule of Income and Expense Line Items | The following tables summarize the amounts recorded in income and expense line items and the effects thereon from fair value and cash flow hedging, including discontinued hedging relationships (in millions):
|  | Year ended December 31, 2024
|  | Product sales |  | Other income (expense), net |  | Interest expense, net
Total amounts recorded in income and (expense) line items presented in the Consolidated Statements of Income |  | $ | 32,026 |  |  | $ | 506 |  |  | $ | (3,155) |
The effects of cash flow and fair value hedging: |  |  |  |  |  |
Gains (losses) on cash flow hedging relationships reclassified out of AOCI: |  |  |  |  |  |
Foreign currency forward contracts |  | $ | 192 |  |  | $ | — |  |  | $ | — |
Cross-currency swap contracts |  | $ | — |  |  | $ | (75) |  |  | $ | — |
Gains on fair value hedging relationships—interest rate swap agreements: |  |  |  |  |  |
Hedged items(1) |  | $ | — |  |  | $ | — |  |  | $ | 29 |
Derivatives designated as hedging instruments |  | $ | — |  |  | $ | — |  |  | $ | 40 |
|  | Year ended December 31, 2023
|  | Product sales |  | Other income (expense), net |  | Interest expense, net
Total amounts recorded in income and (expense) line items presented in the Consolidated Statements of Income |  | $ | 26,910 |  |  | $ | 2,833 |  |  | $ | (2,875) |
The effects of cash flow and fair value hedging: |  |  |  |  |  |
Gains on cash flow hedging relationships reclassified out of AOCI: |  |  |  |  |  |
Foreign currency forward contracts |  | $ | 180 |  |  | $ | — |  |  | $ | — |
Cross-currency swap contracts |  | $ | — |  |  | $ | 42 |  |  | $ | — |
(Losses) gains on fair value hedging relationships—interest rate swap agreements: |  |  |  |  |  |
Hedged items(1) |  | $ | — |  |  | $ | — |  |  | $ | (118) |
Derivatives designated as hedging instruments |  | $ | — |  |  | $ | — |  |  | $ | 205 |
|  | Year ended December 31, 2022
|  | Product sales |  | Other income (expense), net |  | Interest expense, net
Total amounts recorded in income and (expense) line items presented in the Consolidated Statements of Income |  | $ | 24,801 |  |  | $ | (814) |  |  | $ | (1,406) |
The effects of cash flow and fair value hedging: |  |  |  |  |  |
Gains (losses) on cash flow hedging relationships reclassified out of AOCI: |  |  |  |  |  |
Foreign currency forward contracts |  | $ | 231 |  |  | $ | — |  |  | $ | — |
Cross-currency swap contracts |  | $ | — |  |  | $ | (233) |  |  | $ | — |
Gains (losses) on fair value hedging relationships—interest rate swap agreements: |  |  |  |  |  |
Hedged items(1) |  | $ | — |  |  | $ | — |  |  | $ | 716 |
Derivatives designated as hedging instruments |  | $ | — |  |  | $ | — |  |  | $ | (636) |
__________ (1) Gains (losses) on hedged items do not exactly offset losses (gains) on the related designated hedging instruments due to amortization of the cumulative amounts of fair value hedging adjustments included in the carrying amount of the hedged debt for discontinued hedging relationships and the recognition of gains on terminated hedges when the corresponding hedged item was paid down in the period.
Schedule of Fair Value of Derivatives | The fair values of derivatives included in the Consolidated Balance Sheets were as follows (in millions):
|  | Derivative assets |  | Derivative liabilities
December 31, 2024 |  | Consolidated Balance Sheets locations |  | Fair values |  | Consolidated Balance Sheets locations |  | Fair values
Derivatives designated as hedging instruments: |  |  |  |  |  |  |  |
Foreign currency forward contracts |  | Other current assets/ Other noncurrent assets |  | $ | 420 |  |  | Accrued liabilities/ Other noncurrent liabilities |  | $ | 8 |
Cross-currency swap contracts |  | Other current assets/ Other noncurrent assets |  | — |  |  | Accrued liabilities/ Other noncurrent liabilities |  | 483 |
Interest rate swap contracts |  | Other current assets/ Other noncurrent assets |  | — |  |  | Accrued liabilities/ Other noncurrent liabilities |  | 531 |
Total derivatives designated as hedging instruments |  |  |  | 420 |  |  |  |  | 1,022 |
Total derivatives |  |  |  | $ | 420 |  |  |  |  | $ | 1,022 |
|  | Derivative assets |  | Derivative liabilities
December 31, 2023 |  | Consolidated Balance Sheets locations |  | Fair values |  | Consolidated Balance Sheets locations |  | Fair values
Derivatives designated as hedging instruments: |  |  |  |  |  |  |  |
Foreign currency forward contracts |  | Other current assets/ Other noncurrent assets |  | $ | 145 |  |  | Accrued liabilities/ Other noncurrent liabilities |  | $ | 116 |
Cross-currency swap contracts |  | Other current assets/ Other noncurrent assets |  | — |  |  | Accrued liabilities/ Other noncurrent liabilities |  | 405 |
Interest rate swap contracts |  | Other current assets/ Other noncurrent assets |  | — |  |  | Accrued liabilities/ Other noncurrent liabilities |  | 571 |
Total derivatives designated as hedging instruments |  |  |  | 145 |  |  |  |  | 1,092 |
Total derivatives |  |  |  | $ | 145 |  |  |  |  | $ | 1,092 |
For additional information, see Note 18, Fair value measurement.

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