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Derivative instruments - Schedule of Income and Expense Line Items (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Derivative Instruments, Gain (Loss) [Line Items]    
Product sales $ 8,149 $ 7,447
Other income (expense), net 1,518 (235)
Interest expense, net (723) (824)
Cross-currency swap contracts | Reclassification out of AOCI | Cash flow hedges    
Derivative Instruments, Gain (Loss) [Line Items]    
Other income (expense), net 83 (31)
Interest rate swap agreements    
Derivative Instruments, Gain (Loss) [Line Items]    
Gains (losses) on fair value hedging relationships, hedged items (96) 49
Derivatives designated as hedging instruments 112 (28)
Product sales    
Derivative Instruments, Gain (Loss) [Line Items]    
Product sales 7,873 7,118
Product sales | Foreign currency forward contracts | Reclassification out of AOCI | Cash flow hedges    
Derivative Instruments, Gain (Loss) [Line Items]    
Product sales $ 56 $ 51