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Contingent Consideration (Details) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration [Abstract] |  |  |
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Purchases | $ 0 | $ 127 | $ 248
Business Combination, Provisional Information, Initial Accounting Incomplete, Adjustment, Consideration Transferred |  | (16) |
Payment of contingent consideration | 58 | 68 |
Contingent consideration net expense (benefit) | (100) | (35) | (21)
Business Combination, Contingent Consideration Arrangements [Abstract] |  |  |
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High | 532 |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |  |
Business Combination, Contingent Consideration, Liability | $ 196 | $ 354 | $ 347
Valuation Technique, Discounted Cash Flow [Member] | R&D, Regulatory and Commercialization-based Milestone [Member] |  |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |  |
contingent consideration liability, probability of payment | 90.00% |  |
Discount Rate, Fair Value Input | 2.00% |  |
Business Combination, Contingent Consideration, Liability | $ 104 |  |
Valuation Technique, Discounted Cash Flow [Member] | revenue-based payments [Member] |  |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |  |
Business Combination, Contingent Consideration, Liability | $ 93 |  |
Minimum [Member] | Valuation Technique, Discounted Cash Flow [Member] | revenue-based payments [Member] |  |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |  |
contingent consideration liability, probability of payment | 80.00% |  |
Discount Rate, Fair Value Input | 12.00% |  |
Maximum [Member] | Valuation Technique, Discounted Cash Flow [Member] | revenue-based payments [Member] |  |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |  |
contingent consideration liability, probability of payment | 100.00% |  |
Discount Rate, Fair Value Input | 14.00% |  |
Weighted Average (Member) | Valuation Technique, Discounted Cash Flow [Member] | R&D, Regulatory and Commercialization-based Milestone [Member] |  |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |  |
contingent consideration liability, probability of payment | 90.00% |  |
Discount Rate, Fair Value Input | 2.00% |  |
Weighted Average (Member) | Valuation Technique, Discounted Cash Flow [Member] | revenue-based payments [Member] |  |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |  |
contingent consideration liability, probability of payment | 100.00% |  |
Discount Rate, Fair Value Input | 13.00% |  |

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- Definition Discount Rate, Fair Value Input + References No definition available. + Details
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- Definition Amount of increase (decrease) in the value of a contingent consideration liability, including, but not limited to, differences arising upon settlement. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=121586364&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 50 -Paragraph 4 -Subparagraph (a)(1) -URI http://asc.fasb.org/extlink&oid=120321790&loc=d3e7008-128479 + Details
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- Definition For contingent consideration arrangements recognized in connection with a business combination, this element represents an estimate of the high-end of the potential range (undiscounted) of the consideration which may be paid. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (c)(3) -URI http://asc.fasb.org/extlink&oid=120321790&loc=d3e6927-128479 + Details
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- Definition Amount of liability recognized arising from contingent consideration in a business combination. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=120321790&loc=d3e6927-128479 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 35 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=116859824&loc=d3e6819-128478 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 25 -Paragraph 6 -URI http://asc.fasb.org/extlink&oid=6911189&loc=d3e6408-128476 + Details
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- Definition This element represents the amount of any measurement period adjustment (as defined) realized during the reporting period to items of consideration transferred in connection with a business combination for which the initial accounting was incomplete. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 20 -Section 50 -Paragraph 4A -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=121647850&loc=SL65897772-128472 + Details
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- Definition Amount of purchases of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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