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Contingent Consideration (Details) - USD ($) $ in Millions | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration [Abstract] |  |
Business Combination, Contingent Consideration, Liability Beginning Balance | $ 486 |
Fair value of contingent consideration recorded in purchase accounting | 0 | $ 219
Contingent consideration net expense (benefit) | 12 | $ (6)
Payment of contingent consideration | (41) |
Business Combination, Contingent Consideration, Liability Ending Balance | 456 |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |
Business Combination, Contingent Consideration, Liability | 456 |
All Business Acquisitions |  |
Business Combination, Contingent Consideration Arrangements [Abstract] |  |
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High | 964 |
Valuation Technique, Discounted Cash Flow [Member] | R&D, Regulatory and Commercialization-based Milestone [Member] |  |
Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration [Abstract] |  |
Business Combination, Contingent Consideration, Liability Ending Balance | 147 |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |
Business Combination, Contingent Consideration, Liability | 147 |
Valuation Technique, Discounted Cash Flow [Member] | revenue-based payments [Member] |  |
Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration [Abstract] |  |
Business Combination, Contingent Consideration, Liability Ending Balance | 308 |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |
Business Combination, Contingent Consideration, Liability | $ 308 |
contingent consideration liability, probability of payment | 100.00% |
Minimum [Member] | Valuation Technique, Discounted Cash Flow [Member] | R&D, Regulatory and Commercialization-based Milestone [Member] |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |
contingent consideration liability, probability of payment | 80.00% |
Discount Rate, Fair Value Input | 1.00% |
Minimum [Member] | Valuation Technique, Discounted Cash Flow [Member] | revenue-based payments [Member] |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |
Discount Rate, Fair Value Input | 4.00% |
Maximum [Member] | Valuation Technique, Discounted Cash Flow [Member] | R&D, Regulatory and Commercialization-based Milestone [Member] |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |
contingent consideration liability, probability of payment | 100.00% |
Discount Rate, Fair Value Input | 2.00% |
Maximum [Member] | Valuation Technique, Discounted Cash Flow [Member] | revenue-based payments [Member] |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |
Discount Rate, Fair Value Input | 14.00% |
Weighted Average [Member] | Valuation Technique, Discounted Cash Flow [Member] | R&D, Regulatory and Commercialization-based Milestone [Member] |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |
contingent consideration liability, probability of payment | 92.00% |
Discount Rate, Fair Value Input | 1.00% |
Weighted Average [Member] | Valuation Technique, Discounted Cash Flow [Member] | revenue-based payments [Member] |  |
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract] |  |
contingent consideration liability, probability of payment | 100.00% |
Discount Rate, Fair Value Input | 6.00% |

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- Definition Amount of increase (decrease) in the value of a contingent consideration liability, including, but not limited to, differences arising upon settlement. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 50 -Paragraph 4 -Subparagraph (a)(1) -URI http://asc.fasb.org/extlink&oid=120321790&loc=d3e7008-128479 + Details
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- Definition For contingent consideration arrangements recognized in connection with a business combination, this element represents an estimate of the high-end of the potential range (undiscounted) of the consideration which may be paid. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (c)(3) -URI http://asc.fasb.org/extlink&oid=120321790&loc=d3e6927-128479 + Details
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- Definition Amount of purchases of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258 + Details
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