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Hedging Activities and Fair Value Measurements (Details)
€ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2022
USD ($)
derivative_instrument
units
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
derivative_instrument
units
Sep. 30, 2021
USD ($)
Sep. 30, 2022
EUR (€)
units
derivative_instrument
Jun. 30, 2022
USD ($)
Dec. 31, 2021
USD ($)
derivative_instrument
Jun. 30, 2021
USD ($)
Dec. 31, 2020
USD ($)
Derivative Instruments, Gain (Loss) [Line Items]                  
AOCI, Cash Flow Hedge, Cumulative Gain (Loss), after Tax $ 434,000,000 $ 196,000,000 $ 434,000,000 $ 196,000,000   $ 363,000,000 $ 206,000,000 $ 146,000,000 $ 36,000,000
Derivative, Notional Amount 7,877,000,000   7,877,000,000       9,378,000,000    
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, after Tax 119,000,000 61,000,000 319,000,000 182,000,000          
Cost of Goods and Services Sold 979,000,000 900,000,000 2,945,000,000 2,739,000,000          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, after Tax 47,000,000 11,000,000 90,000,000 21,000,000          
Interest Expense 63,000,000 86,000,000 406,000,000 254,000,000          
Other Operating Income (Expense), Net 51,000,000 (181,000,000) 96,000,000 (192,000,000)          
Derivative Asset, Fair Value, Gross Asset 652,000,000   652,000,000       394,000,000    
Derivative Liability, Fair Value, Gross Liability 942,000,000   942,000,000       1,071,000,000    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Equity Securities, FV-NI 3,000,000   3,000,000       10,000,000    
Derivative Asset 285,000,000   285,000,000       169,000,000    
Licensing arrangements, asset 78,000,000   78,000,000       114,000,000    
Business Combination, Contingent Consideration, Liability 182,000,000   182,000,000       486,000,000    
Licensing arrangements, liability 84,000,000   84,000,000       143,000,000    
Cash 242,000,000   242,000,000       293,000,000    
Non-cash impact of transferred royalty rights (54,000,000) (62,000,000) (54,000,000) (62,000,000)          
Debt Instrument, Fair Value Disclosure 7,790,000,000   7,790,000,000       10,196,000,000    
Accumulated Foreign Currency Adjustment Attributable to Parent                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Reclassification from AOCI, Current Period, Net of Tax, Attributable to Parent 0 0 0 0          
December 2027 Notes [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Long-term Debt $ 879,000,000   $ 879,000,000   € 900   1,021,000,000    
Debt Instrument, Interest Rate, Stated Percentage 0.625%   0.625%   0.625%        
Licensing arrangement assets [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Discount Rate, Fair Value Input 15.00%   15.00%   15.00%        
Proceeds from Royalties Received     $ (108,000,000)            
Increase (Decrease) in Fair Value Adjustments on Other Assets (Liabilities) Carried at Fair Value under Fair Value Option     14,000,000            
Licensing arrangement liabilities [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Payments for Royalties     (129,000,000)            
Increase (Decrease) in Fair Value Adjustments on Other Assets (Liabilities) Carried at Fair Value under Fair Value Option     15,000,000            
Fair Value, Inputs, Level 3 [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Licensing arrangements, asset $ 151,000,000   151,000,000            
Licensing arrangements, liability 167,000,000   167,000,000            
Fair Value, Measurements, Recurring [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Money Market Funds, at Carrying Value 95,000,000   95,000,000       1,632,000,000    
Equity Securities, FV-NI 3,000,000   3,000,000       10,000,000    
Derivative Asset 652,000,000   652,000,000       394,000,000    
Licensing arrangements, asset 151,000,000   151,000,000       246,000,000    
Assets, Fair Value Disclosure 902,000,000   902,000,000       2,282,000,000    
Derivative Liability 942,000,000   942,000,000       1,071,000,000    
Business Combination, Contingent Consideration, Liability 182,000,000   182,000,000       486,000,000    
Licensing arrangements, liability 167,000,000   167,000,000       281,000,000    
Financial and Nonfinancial Liabilities, Fair Value Disclosure 1,291,000,000   1,291,000,000       1,838,000,000    
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Money Market Funds, at Carrying Value 95,000,000   95,000,000       1,632,000,000    
Equity Securities, FV-NI 3,000,000   3,000,000       10,000,000    
Derivative Asset 0   0       0    
Licensing arrangements, asset 0   0       0    
Assets, Fair Value Disclosure 99,000,000   99,000,000       1,642,000,000    
Derivative Liability 0   0       0    
Business Combination, Contingent Consideration, Liability 0   0       0    
Licensing arrangements, liability 0   0       0    
Financial and Nonfinancial Liabilities, Fair Value Disclosure 0   0       0    
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Money Market Funds, at Carrying Value 0   0       0    
Equity Securities, FV-NI 0   0       0    
Derivative Asset 652,000,000   652,000,000       394,000,000    
Licensing arrangements, asset 0   0       0    
Assets, Fair Value Disclosure 652,000,000   652,000,000       394,000,000    
Derivative Liability 942,000,000   942,000,000       1,071,000,000    
Business Combination, Contingent Consideration, Liability 0   0       0    
Licensing arrangements, liability 0   0       0    
Financial and Nonfinancial Liabilities, Fair Value Disclosure 942,000,000   942,000,000       1,071,000,000    
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Money Market Funds, at Carrying Value 0   0       0    
Equity Securities, FV-NI 0   0       0    
Derivative Asset 0   0       0    
Licensing arrangements, asset 151,000,000   151,000,000       246,000,000    
Assets, Fair Value Disclosure 151,000,000   151,000,000       246,000,000    
Derivative Liability 0   0       0    
Business Combination, Contingent Consideration, Liability 182,000,000   182,000,000       486,000,000    
Licensing arrangements, liability 167,000,000   167,000,000       281,000,000    
Financial and Nonfinancial Liabilities, Fair Value Disclosure 349,000,000   349,000,000       767,000,000    
Designated as Hedging Instrument [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative Instruments in Hedges, Assets, at Fair Value 590,000,000   590,000,000       352,000,000    
Derivative Instruments in Hedges, Liabilities, at Fair Value 875,000,000   875,000,000       1,049,000,000    
Designated as Hedging Instrument [Member] | Other Noncurrent Liabilities [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative Instruments in Hedges, Liabilities, at Fair Value $ 871,000,000   $ 871,000,000       1,011,000,000    
Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Forward Currency Contracts, Time to Maturity | units 60   60   60        
Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member] | Prepaid Expenses and Other Current Assets [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative Instruments in Hedges, Assets, at Fair Value $ 305,000,000   $ 305,000,000       183,000,000    
Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member] | Other Noncurrent Assets [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative Instruments in Hedges, Assets, at Fair Value 285,000,000   285,000,000       169,000,000    
Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member] | Other Current Liabilities [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative Instruments in Hedges, Liabilities, at Fair Value 4,000,000   4,000,000       32,000,000    
Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member] | Other Noncurrent Liabilities [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative Instruments in Hedges, Liabilities, at Fair Value 0   0       6,000,000    
Not Designated as Hedging Instrument [Member] | Other Nonoperating Income (Expense) [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Gain (Loss) on Foreign Currency Derivative Instruments Not Designated as Hedging Instruments (29,000,000) (15,000,000) (93,000,000) (17,000,000)          
Foreign Currency Transaction Gain (Loss), before Tax (8,000,000) 7,000,000 48,000,000 1,000,000          
Net currency exchange gain (loss) (38,000,000) (8,000,000) (45,000,000) (17,000,000)          
Not Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative, Notional Amount 3,432,000,000   3,432,000,000       3,892,000,000    
Not Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member] | Prepaid Expenses and Other Current Assets [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative Instruments Not Designated as Hedging Instruments, Asset, at Fair Value 62,000,000   62,000,000       42,000,000    
Not Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member] | Other Current Liabilities [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative Instruments Not Designated as Hedging Instruments, Liability, at Fair Value $ 67,000,000   $ 67,000,000       $ 22,000,000    
Not Designated as Hedging Instrument [Member] | Foreign Exchange Forward                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative, Term of Contract (less than)     1 year            
Derivative, Remaining Maturity     1 year            
Weighted Average [Member] | Licensing arrangement assets [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Discount Rate, Fair Value Input 15.00%   15.00%   15.00%        
Weighted Average [Member] | Licensing arrangement liabilities [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Discount Rate, Fair Value Input 13.00%   13.00%   13.00%        
Minimum [Member] | Licensing arrangement liabilities [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Discount Rate, Fair Value Input 12.00%   12.00%   12.00%        
Maximum [Member] | Licensing arrangement liabilities [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Discount Rate, Fair Value Input 15.00%   15.00%   15.00%        
Cash Flow Hedging [Member] | Foreign Exchange Contract [Member] | Cost of Sales [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Foreign Currency Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months $ 321,000,000   $ 321,000,000            
Cash Flow Hedging [Member] | Interest Rate Contract [Member] | Interest Expense [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Interest Rate Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months, Net $ (3,000,000)   $ (3,000,000)            
Cash Flow Hedging [Member] | Designated as Hedging Instrument [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Number of Interest Rate Derivatives Held | derivative_instrument 0   0   0   0    
Cash Flow Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative, Notional Amount $ 3,084,000,000   $ 3,084,000,000       $ 3,996,000,000    
Cash Flow Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member] | Cost of Sales [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification and Tax 153,000,000 79,000,000 412,000,000 234,000,000          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, Tax (34,000,000) (18,000,000) (93,000,000) (53,000,000)          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, after Tax 119,000,000 61,000,000 319,000,000 182,000,000          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, before Tax (61,000,000) (16,000,000) (132,000,000) (31,000,000)          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, Tax 14,000,000 3,000,000 30,000,000 7,000,000          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, after Tax (47,000,000) (12,000,000) (102,000,000) (24,000,000)          
Cash Flow Hedging [Member] | Designated as Hedging Instrument [Member] | Interest Rate Contract [Member] | Interest Expense [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification and Tax 0 0 0 0          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, Tax 0 0 0 0          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, after Tax 0 0 0 0          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, before Tax 1,000,000 1,000,000 15,000,000 4,000,000          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, Tax 0 0 (3,000,000) (1,000,000)          
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, after Tax 1,000,000 1,000,000 12,000,000 3,000,000          
Net Investment Hedging [Member] | Foreign Exchange Contract [Member] | Interest Expense [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative Used in Net Investment Hedge Gain (Loss) to be Reclassified During Next 12 Months, Net 10,000,000   10,000,000            
Net Investment Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative, Notional Amount 365,000,000   365,000,000       493,000,000    
Net Investment Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign Exchange Contract [Member] | Interest Expense [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Other Comprehensive Income (Loss), Net Investment Hedge, Gain (Loss), before Reclassification and Tax 14,000,000 7,000,000 63,000,000 50,000,000          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), before Adjustments, Tax (16,000,000) (2,000,000) (14,000,000) (11,000,000)          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), before Adjustments, after Tax (2,000,000) 6,000,000 48,000,000 39,000,000          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), Adjustments, before Tax (3,000,000) (2,000,000) (7,000,000) (11,000,000)          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), Adjustments, Tax 1,000,000 0 2,000,000 3,000,000          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), Adjustments, after Tax (2,000,000) (2,000,000) (6,000,000) (9,000,000)          
Net Investment Hedging [Member] | Designated as Hedging Instrument [Member] | foreign currency denominated in debt [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Derivative, Notional Amount 997,000,000   997,000,000       $ 997,000,000    
Net Investment Hedging [Member] | Designated as Hedging Instrument [Member] | foreign currency denominated in debt [Member] | Interest Expense [Member]                  
Derivative Instruments, Gain (Loss) [Line Items]                  
Other Comprehensive Income (Loss), Net Investment Hedge, Gain (Loss), before Reclassification and Tax 56,000,000 25,000,000 142,000,000 60,000,000          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), before Adjustments, Tax (13,000,000) (6,000,000) (32,000,000) (14,000,000)          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), before Adjustments, after Tax 43,000,000 20,000,000 110,000,000 47,000,000          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), Adjustments, before Tax 0 0 0 0          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), Adjustments, Tax 0 0 0 0          
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), Adjustments, after Tax $ 0 $ 0 $ 0 $ 0