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Summary of Significant Accounting Policies - Recently Adopted Accounting Pronouncements (Details) - USD ($)
$ in Millions
6 Months Ended
Jun. 30, 2018
Jan. 01, 2018
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Cumulative effect from the adoption of new accounting standards   $ 190
Galapagos    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Unrealized gain of investment $ 278  
Accumulated Other Comprehensive Income (Loss)    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Cumulative effect from the adoption of new accounting standards   (293)
Accumulated Other Comprehensive Income (Loss) | Accounting Standards Update 2016-01    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Cumulative effect from the adoption of new accounting standards   (293)
Retained Earnings    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Cumulative effect from the adoption of new accounting standards   483
Retained Earnings | Accounting Standards Update 2016-01    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Cumulative effect from the adoption of new accounting standards   $ 293