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Revenues - Disaggregation of Revenues (Details) - USD ($)
$ in Millions
 3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Disaggregation of Revenue [Line Items]        
Revenues $ 5,596 $ 6,512 $ 16,332 $ 20,158
U.S.        
Disaggregation of Revenue [Line Items]        
Revenues 4,151 4,563 11,781 14,036
Europe        
Disaggregation of Revenue [Line Items]        
Revenues 975 1,271 3,116 4,088
Other International        
Disaggregation of Revenue [Line Items]        
Revenues 470 678 1,435 2,034
Atripla        
Disaggregation of Revenue [Line Items]        
Product revenue 258 439 921 1,366
Atripla | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 221 324 723 974
Atripla | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 29 79 119 259
Atripla | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 8 36 79 133
Biktarvy        
Disaggregation of Revenue [Line Items]        
Product revenue 386 0 606 0
Biktarvy | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 375 0 593 0
Biktarvy | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 11 0 13 0
Biktarvy | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 0 0 0 0
Complera/Eviplera        
Disaggregation of Revenue [Line Items]        
Product revenue 139 237 528 744
Complera/Eviplera | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 61 91 210 315
Complera/Eviplera | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 67 133 279 385
Complera/Eviplera | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 11 13 39 44
Descovy        
Disaggregation of Revenue [Line Items]        
Product revenue 406 316 1,170 853
Descovy | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 310 241 895 682
Descovy | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 81 65 234 149
Descovy | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 15 10 41 22
Genvoya        
Disaggregation of Revenue [Line Items]        
Product revenue 1,176 988 3,418 2,614
Genvoya | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 921 810 2,678 2,189
Genvoya | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 203 146 596 358
Genvoya | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 52 32 144 67
Odefsey        
Disaggregation of Revenue [Line Items]        
Product revenue 423 296 1,150 781
Odefsey | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 323 255 905 688
Odefsey | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 95 37 230 87
Odefsey | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 5 4 15 6
Stribild        
Disaggregation of Revenue [Line Items]        
Product revenue 146 229 507 831
Stribild | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 111 181 388 632
Stribild | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 20 40 83 161
Stribild | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 15 8 36 38
Truvada        
Disaggregation of Revenue [Line Items]        
Product revenue 757 811 2,174 2,337
Truvada | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 665 604 1,821 1,635
Truvada | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 62 154 245 527
Truvada | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 30 53 108 175
Other HIV        
Disaggregation of Revenue [Line Items]        
Product revenue 14 15 46 41
Other HIV | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 10 13 30 34
Other HIV | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 2 2 6 5
Other HIV | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 2 0 10 2
Revenue share - Symtuza        
Disaggregation of Revenue [Line Items]        
Product revenue 22 0 42 0
Revenue share - Symtuza | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 8 0 8 0
Revenue share - Symtuza | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 14 0 34 0
Revenue share - Symtuza | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 0 0 0 0
AmBisome        
Disaggregation of Revenue [Line Items]        
Product revenue 102 92 312 276
AmBisome | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 9 9 40 26
AmBisome | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 59 51 170 153
AmBisome | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 34 32 102 97
Epclusa        
Disaggregation of Revenue [Line Items]        
Product revenue 477 882 1,513 2,945
Epclusa | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 225 543 733 2,142
Epclusa | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 136 263 502 649
Epclusa | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 116 76 278 154
Harvoni        
Disaggregation of Revenue [Line Items]        
Product revenue 311 973 990 3,726
Harvoni | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 185 718 649 2,628
Harvoni | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 38 110 116 583
Harvoni | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 88 145 225 515
Letairis        
Disaggregation of Revenue [Line Items]        
Product revenue 241 213 689 654
Letairis | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 241 213 689 654
Letairis | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 0 0 0 0
Letairis | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 0 0 0 0
Ranexa        
Disaggregation of Revenue [Line Items]        
Product revenue 178 164 581 517
Ranexa | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 178 164 581 517
Ranexa | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 0 0 0 0
Ranexa | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 0 0 0 0
Vemlidy        
Disaggregation of Revenue [Line Items]        
Product revenue 87 37 221 70
Vemlidy | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 66 34 172 66
Vemlidy | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 2 2 8 3
Vemlidy | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 19 1 41 1
Viread        
Disaggregation of Revenue [Line Items]        
Product revenue 70 274 249 834
Viread | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 17 137 40 395
Viread | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 10 55 72 202
Viread | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 43 82 137 237
Vosevi        
Disaggregation of Revenue [Line Items]        
Product revenue 103 123 319 123
Vosevi | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 78 117 250 117
Vosevi | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 21 5 57 5
Vosevi | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 4 1 12 1
Yescarta        
Disaggregation of Revenue [Line Items]        
Product revenue 75 0 183 0
Yescarta | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 75 0 183 0
Yescarta | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 0 0 0 0
Yescarta | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 0 0 0 0
Zydelig        
Disaggregation of Revenue [Line Items]        
Product revenue 20 40 92 110
Zydelig | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 15 18 46 52
Zydelig | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 4 22 44 57
Zydelig | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 1 0 2 1
Other        
Disaggregation of Revenue [Line Items]        
Product revenue 64 273 285 1,003
Other | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 37 70 93 228
Other | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 19 33 75 279
Other | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 8 170 117 496
Product sales        
Disaggregation of Revenue [Line Items]        
Product revenue 5,455 6,402 15,996 19,825
Product sales | U.S.        
Disaggregation of Revenue [Line Items]        
Product revenue 4,131 4,542 11,727 13,974
Product sales | Europe        
Disaggregation of Revenue [Line Items]        
Product revenue 873 1,197 2,883 3,862
Product sales | Other International        
Disaggregation of Revenue [Line Items]        
Product revenue 451 663 1,386 1,989
Royalty, contract and other revenues        
Disaggregation of Revenue [Line Items]        
Revenues 141 110 336 333
Royalty, contract and other revenues | U.S.        
Disaggregation of Revenue [Line Items]        
Revenues 20 21 54 62
Royalty, contract and other revenues | Europe        
Disaggregation of Revenue [Line Items]        
Revenues 102 74 233 226
Royalty, contract and other revenues | Other International        
Disaggregation of Revenue [Line Items]        
Revenues $ 19 $ 15 $ 49 $ 45