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Organization and Summary of Significant Accounting Policies - Narrative (Details) - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Organization And Summary Of Significant Accounting Policies [Line Items]      
Advertising expense $ 795,000,000 $ 784,000,000 $ 587,000,000
Write-offs charged against allowance $ 0    
Buildings and improvements      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Property, plant and equipment, useful life 35 years    
Minimum | Laboratory and manufacturing equipment      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Property, plant and equipment, useful life 4 years    
Minimum | Office, computer equipment and other      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Property, plant and equipment, useful life 3 years    
Maximum | Laboratory and manufacturing equipment      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Property, plant and equipment, useful life 10 years    
Maximum | Office, computer equipment and other      
Organization And Summary Of Significant Accounting Policies [Line Items]      
Property, plant and equipment, useful life 15 years