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Employee Benefits - Summary of Stock-Based Compensation (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses $ 1,076 $ 636 $ 845
Income tax effect (222) 2 (164)
Stock-based compensation expense, net of tax 854 638 681
Stock-based compensation expense 643 636 845
Income tax expense following U.S. Court of Appeals decision   114  
Forty Seven, Inc.      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Accelerated stock-based expense 144    
Immunomedics, Inc.      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Accelerated stock-based expense 289    
Cost of goods sold      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 109 48 61
Research and development expenses      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 462 289 379
Selling, general and administrative expenses      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses $ 505 $ 299 $ 405