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Other Financial Information - Other Accrued Liabilities (Details) - USD ($) $ in Millions | Dec. 31, 2021 | Dec. 31, 2020
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Other Financial Information [Abstract] |  |
Compensation and employee benefits | $ 927 | $ 864
Income taxes payable | 539 | 598
Allowance for sales returns | 499 | 587
Accrual for settlement related to bictegravir litigation | 1,250 | 0
Other accrued liabilities | 2,930 | 2,287
Accrued and other current liabilities | $ 6,145 | $ 4,336

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