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Debt and Credit Facilities (Tables) | 12 Months Ended
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Dec. 31, 2021
Debt Disclosure [Abstract] |
Summary of Financing Arrangements | The following table summarizes the carrying amount of our borrowings under various financing arrangements:
(in millions) |  | December 31,
Type of Borrowing |  | Issue Date |  | Due Date |  | Interest Rate |  | 2021 |  | 2020
Senior Unsecured |  | March 2011 |  | April 2021 |  | 4.50% |  | $ | — |  |  | $ | 1,000 |
Senior Unsecured |  | September 2020 |  | September 2021 |  | 3-month LIBOR + 0.15% |  | — |  |  | 499 |
Senior Unsecured |  | December 2011 |  | December 2021 |  | 4.40% |  | — |  |  | 1,249 |
Senior Unsecured |  | September 2016 |  | March 2022 |  | 1.95% |  | 500 |  |  | 499 |
Senior Unsecured |  | September 2015 |  | September 2022 |  | 3.25% |  | 999 |  |  | 998 |
Senior Unsecured |  | September 2016 |  | September 2023 |  | 2.50% |  | 748 |  |  | 748 |
Senior Unsecured |  | September 2020 |  | September 2023 |  | 3-month LIBOR + 0.52% |  | — |  |  | 498 |
Senior Unsecured |  | September 2020 |  | September 2023 |  | 0.75% |  | 1,496 |  |  | 1,992 |
Term Loan |  | October 2020 |  | October 2023 |  | variable |  | — |  |  | 998 |
Senior Unsecured |  | March 2014 |  | April 2024 |  | 3.70% |  | 1,747 |  |  | 1,746 |
Senior Unsecured |  | November 2014 |  | February 2025 |  | 3.50% |  | 1,747 |  |  | 1,746 |
Senior Unsecured |  | September 2015 |  | March 2026 |  | 3.65% |  | 2,739 |  |  | 2,737 |
Senior Unsecured |  | September 2016 |  | March 2027 |  | 2.95% |  | 1,247 |  |  | 1,246 |
Senior Unsecured |  | September 2020 |  | October 2027 |  | 1.20% |  | 746 |  |  | 745 |
Senior Unsecured |  | September 2020 |  | October 2030 |  | 1.65% |  | 993 |  |  | 992 |
Senior Unsecured |  | September 2015 |  | September 2035 |  | 4.60% |  | 992 |  |  | 991 |
Senior Unsecured |  | September 2016 |  | September 2036 |  | 4.00% |  | 742 |  |  | 741 |
Senior Unsecured |  | September 2020 |  | October 2040 |  | 2.60% |  | 987 |  |  | 986 |
Senior Unsecured |  | December 2011 |  | December 2041 |  | 5.65% |  | 996 |  |  | 996 |
Senior Unsecured |  | March 2014 |  | April 2044 |  | 4.80% |  | 1,736 |  |  | 1,735 |
Senior Unsecured |  | November 2014 |  | February 2045 |  | 4.50% |  | 1,733 |  |  | 1,732 |
Senior Unsecured |  | September 2015 |  | March 2046 |  | 4.75% |  | 2,220 |  |  | 2,219 |
Senior Unsecured |  | September 2016 |  | March 2047 |  | 4.15% |  | 1,727 |  |  | 1,726 |
Senior Unsecured |  | September 2020 |  | October 2050 |  | 2.80% |  | 1,476 |  |  | 1,476 |
Total senior unsecured notes and term loan facility |  | 25,571 |  |  | 30,295 |
Liability related to future royalties |  | 1,124 |  |  | 1,107 |
Total debt, net |  | 26,695 |  |  | 31,402 |
Less: current portion of long-term debt and other obligations, net |  | 1,516 |  |  | 2,757 |
Total long-term debt, net |  | $ | 25,179 |  |  | $ | 28,645 |
Schedule of Contractual Maturities of Financing Obligations | The following table summarizes the aggregate future principal maturities of our senior unsecured notes as of December 31, 2021:
(in millions) |  | Amount
2022 |  | $ | 1,500 |
2023 |  | 2,250 |
2024 |  | 1,750 |
2025 |  | 1,750 |
2026 |  | 2,750 |
Thereafter |  | 15,750 |
Total |  | $ | 25,750 |

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