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Derivative Financial Instruments (Tables)
12 Months Ended
Dec. 31, 2021
Derivative Instruments and Hedging Activities Disclosure [Abstract]  
Summary of Classification and Fair Value of Derivative Instruments The following table summarizes the classification and fair values of derivative instruments in our Consolidated Balance Sheets:
December 31, 2021
 Derivative Assets Derivative Liabilities
(in millions)Classification
Fair Value
ClassificationFair
Value
Derivatives designated as hedges:
Foreign currency exchange contracts
Prepaid and other current assets$75 Accrued and other current liabilities$
Foreign currency exchange contracts
Other long-term assetsOther long-term obligations
Total derivatives designated as hedges
80 
Derivatives not designated as hedges:
Foreign currency exchange contracts
Prepaid and other current assets— Accrued and other current liabilities— 
Total derivatives not designated as hedges
— — 
Total derivatives$80 $
December 31, 2020
Derivative AssetsDerivative Liabilities
(in millions)Classification
Fair Value
ClassificationFair
Value
Derivatives designated as hedges:
Foreign currency exchange contracts
Prepaid and other current assets$— Accrued and other current liabilities$113 
Foreign currency exchange contracts
Other long-term assets— Other long-term obligations
Total derivatives designated as hedges
— 120 
Derivatives not designated as hedges:
Foreign currency exchange contracts
Prepaid and other current assets12 Accrued and other current liabilities
Total derivatives not designated as hedges
12 
Total derivatives$12 $121 
Summary of Effect of Foreign Currency Exchange Contracts
The following table summarizes the effect of our foreign currency exchange contracts on our Consolidated Financial Statements:
Year Ended December 31,
(in millions)202120202019
Derivatives designated as hedges:  
Gain (loss) recognized in AOCI$147 $(118)$76 
Gain (loss) reclassified from AOCI into Product sales
$(67)$47 $127 
Derivatives not designated as hedges:   
Gain (loss) recognized in Other income (expense), net$21 $(51)$22 
Summary of Potential Effect of Offsetting Derivatives The following table summarizes the potential effect of offsetting our foreign currency exchange contracts on our Consolidated Balance Sheets:
Gross Amounts Not Offset on the Consolidated Balance Sheets
(in millions)Gross Amounts of Recognized Assets/LiabilitiesGross Amounts Offset on the Consolidated Balance SheetsAmounts of Assets/Liabilities Presented on the Consolidated Balance SheetsDerivative Financial InstrumentsCash Collateral Received/PledgedNet Amount (Legal Offset)
As of December 31, 2021
Derivative assets$80 $— $80 $(4)$— $76 
Derivative liabilities$$— $$(4)$— $
As of December 31, 2020
Derivative assets$12 $— $12 $(12)$— $— 
Derivative liabilities$121 $— $121 $(12)$— $109