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Goodwill and Intangible Assets (Tables)

12 Months Ended

Dec. 31, 2021

Goodwill and Intangible Assets Disclosure [Abstract]

Goodwill

The following table summarizes the changes in the carrying amount of Goodwill:

						December 31,
(in millions)						2021						2020
Beginning balance						$	8,108					$	4,117
Goodwill resulting from acquisitions						226						3,991
Measurement period adjustments						(2)						—
Ending balance						$	8,332					$	8,108

Indefinite-Lived Intangible Assets

The following table summarizes our Intangible assets, net:

						December 31, 2021																								December 31, 2020
(in millions)						Gross  Carrying Amount						Accumulated Amortization						Foreign Currency Translation Adjustment						Net Carrying Amount						Gross  Carrying Amount						Accumulated Amortization						Foreign Currency Translation Adjustment						Net Carrying Amount
Finite-lived assets
Intangible asset - sofosbuvir						$	10,720					$	(5,651)					$	—					$	5,069					$	10,720					$	(4,952)					$	—					$	5,768
Intangible asset - axicabtagene ciloleucel(1)						7,110						(1,501)						—						5,609						6,200						(1,105)						—						5,095
Intangible asset - Trodelvy(2)						5,630						(507)						—						5,123						4,600						(63)						—						4,537
Intangible asset - Hepcludex						845						(72)						—						773						—						—						—						—
Other(3)						1,610						(650)						1						961						1,377						(540)						(1)						836
Total finite-lived assets						25,915						(8,381)						1						17,535						22,897						(6,660)						(1)						16,236
Indefinite-lived assets - IPR&D(4)						15,920						—						—						15,920						16,890						—						—						16,890
Total intangible assets						$	41,835					$	(8,381)					$	1					$	33,455					$	39,787					$	(6,660)					$	(1)					$	33,126

________________________________

(1)     Gross carrying amount as of December 31, 2021 includes $910 million reclassified in the first quarter of 2021 from indefinite-lived assets - IPR&D following the March 2021 FDA approval of Yescarta for the treatment of adult patients with relapsed or refractory follicular lymphoma.

(2)     Gross carrying amount as of December 31, 2021 includes Trodelvy for metastatic TNBC and Trodelvy for use in adult patients with locally advanced or metastatic UC. The amount related to UC of $1.0 billion was reclassified to finite-lived assets from indefinite-lived assets - IPR&D upon the accelerated approval by FDA in April 2021.

(3)     In October 2021, FDA granted approval of Tecartus for the treatment of adult patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia. Accordingly, the related amount of $200 million was reclassified to finite-lived assets in the fourth quarter of 2021.

(4)    Gross carrying amount as of December 31, 2021 includes IPR&D from our 2021 acquisition of MYR and remaining IPR&D from our 2020 acquisition of Immunomedics. Gross carrying amount as of December 31, 2020 includes IPR&D from our 2020 acquisition of Immunomedics and remaining IPR&D from our 2017 acquisition of Kite.

Finite-Lived Intangible Assets

The following table summarizes our Intangible assets, net:

						December 31, 2021																								December 31, 2020
(in millions)						Gross  Carrying Amount						Accumulated Amortization						Foreign Currency Translation Adjustment						Net Carrying Amount						Gross  Carrying Amount						Accumulated Amortization						Foreign Currency Translation Adjustment						Net Carrying Amount
Finite-lived assets
Intangible asset - sofosbuvir						$	10,720					$	(5,651)					$	—					$	5,069					$	10,720					$	(4,952)					$	—					$	5,768
Intangible asset - axicabtagene ciloleucel(1)						7,110						(1,501)						—						5,609						6,200						(1,105)						—						5,095
Intangible asset - Trodelvy(2)						5,630						(507)						—						5,123						4,600						(63)						—						4,537
Intangible asset - Hepcludex						845						(72)						—						773						—						—						—						—
Other(3)						1,610						(650)						1						961						1,377						(540)						(1)						836
Total finite-lived assets						25,915						(8,381)						1						17,535						22,897						(6,660)						(1)						16,236
Indefinite-lived assets - IPR&D(4)						15,920						—						—						15,920						16,890						—						—						16,890
Total intangible assets						$	41,835					$	(8,381)					$	1					$	33,455					$	39,787					$	(6,660)					$	(1)					$	33,126

________________________________

(1)     Gross carrying amount as of December 31, 2021 includes $910 million reclassified in the first quarter of 2021 from indefinite-lived assets - IPR&D following the March 2021 FDA approval of Yescarta for the treatment of adult patients with relapsed or refractory follicular lymphoma.

(2)     Gross carrying amount as of December 31, 2021 includes Trodelvy for metastatic TNBC and Trodelvy for use in adult patients with locally advanced or metastatic UC. The amount related to UC of $1.0 billion was reclassified to finite-lived assets from indefinite-lived assets - IPR&D upon the accelerated approval by FDA in April 2021.

(3)     In October 2021, FDA granted approval of Tecartus for the treatment of adult patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia. Accordingly, the related amount of $200 million was reclassified to finite-lived assets in the fourth quarter of 2021.

(4)    Gross carrying amount as of December 31, 2021 includes IPR&D from our 2021 acquisition of MYR and remaining IPR&D from our 2020 acquisition of Immunomedics. Gross carrying amount as of December 31, 2020 includes IPR&D from our 2020 acquisition of Immunomedics and remaining IPR&D from our 2017 acquisition of Kite.

Estimated Future Amortization Expense of Finite-Lived Intangible Assets

The following table summarizes the estimated future amortization expense associated with our finite-lived intangible assets as of December 31, 2021:

(in millions)						Amount
2022						$	1,778
2023						1,778
2024						1,778
2025						1,773
2026						1,765
Thereafter						8,663
Total						$	17,535

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