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Commitments and Contingencies (Details)
$ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Feb. 01, 2022
Oct. 31, 2021
patent
Apr. 30, 2020
plaintiff
agreement
Dec. 31, 2019
USD ($)
patent
opposingParty
Mar. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Sep. 30, 2021
USD ($)
Dec. 31, 2021
USD ($)
lawsuit
plaintiff
Dec. 31, 2016
party
Other Commitments [Line Items]                  
Number of additional patents allegedly infringed | patent   2              
Number of patents allegedly infringed, scenario two | patent       2          
Number of patents allegedly infringed, scenario one | patent       4          
Purchase commitments, year one           $ 1,100   $ 1,100  
Purchase commitments, year two           450   450  
Purchase commitments, year three           243   243  
Purchase commitments, year four           60   60  
Purchase commitments, year five           31   $ 31  
ViiV                  
Other Commitments [Line Items]                  
Pre-tax charge to cost of goods sold           $ 1,250      
ViiV | Forecast                  
Other Commitments [Line Items]                  
Payments for legal settlements         $ 1,250        
ViiV | Subsequent event                  
Other Commitments [Line Items]                  
Royalty percentage on future sales 3.00%                
Juno                  
Other Commitments [Line Items]                  
Amount reversed against previously recorded litigation accrual             $ 175    
Damages awarded       $ 585          
Running royalty rate from October 2017       27.60%          
Enhanced damages on past sales     50.00%            
Running royalty rate on future sales     27.60%            
Pre-Exposure Prophylaxis                  
Other Commitments [Line Items]                  
Number of material transfer agreements | agreement     4            
European Patent Claims 2024 Expiration                  
Other Commitments [Line Items]                  
Number of parties appealed | opposingParty       2          
European Patent Claims 2026 Expiration                  
Other Commitments [Line Items]                  
Number of parties appealed | opposingParty       3          
European Patent Claims 2032 Expiration                  
Other Commitments [Line Items]                  
Number of parties appealed | opposingParty       3          
European Patent Claims 2027 Expiration                  
Other Commitments [Line Items]                  
Number of parties appealed | opposingParty       2          
Number of parties filing opposition | party                 3
Product Liability                  
Other Commitments [Line Items]                  
Number of claims filed | lawsuit               1  
Number of plaintiffs | plaintiff               27,000  
Qui Tam                  
Other Commitments [Line Items]                  
Number of plaintiffs | plaintiff     2